Case Report
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Auditory Hallucination Associated With Metronidazole: A Case Report

Year 2024, Volume: 6 Issue: 3, 59 - 60, 31.12.2024
https://doi.org/10.51262/ejtox.1585902
https://izlik.org/JA52KG92ET

Abstract

This article presents a case of auditory hallucinations occurring in a mentally healthy young patient, which are associated with the administration of metronidazole. A 43-year-old female patient presented to the emergency department with complaints of auditory hallucinations, altered consciousness, and nausea after the use of metronidazole. During the physical examination, the patient was alert, oriented, and cooperative; cranial nerve examination, sensory and motor functions, and cerebellar tests were all normal; no signs of meningeal irritation were detected. This case underscores the importance of being vigilant regarding the potential neurological side effects associated with metronidazole use.

Ethical Statement

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Supporting Institution

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Project Number

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References

  • Revollo JY, Lowder JC, Pierce AS, Twilla JD. Urine Discoloration Associated With Metronidazole: A Rare Occurrence. Journal of Pharmacy Technology. 2014; 30(2): 54–6.
  • Özel Ö, Cesur S, Ataman Hatipoğlu Ç, Altun Demircan Ş, Kaya Kılıç E, Kınıklı S, et al. Metronidazol tedavisine bağlı olarak lökopeni ve trombositopeni gelişen akut gastroenterit olgusu. Turk J Clin Lab. 2017; 8(1): 32-4.
  • Gussago S, Bastone CP, Celio D, Arigoni M, Quarenghi MC. Metronidazole and Peripheral Neuropathy: A Report of Two Cases of (Unusual) Side Effects. Cureus. 2022; 31;14(10):e30889.
  • Altunışık E, Eke Kurt ŞZ. Transient Encephalopathy with A Single Dose of Oral Metronidazole: A Case Report. Turk J Neurol. 2021; 27: 82-4.
  • Khandheria M, Snook E, Thomas C. Psychotic episode secondary to metronidazole use. General Hospital Psychiatry. 2014; 36: 231.e3–231.e4.
  • Testa A, Giannuzzi R, Sollazzo F, Petrongolo L, Bernardini L, Dain S. Psychiatric emergencies (part II): psychiatric disorders coexisting with organic diseases. Eur Rev Med Pharmacol Sci. 2013; 17 (1): 65-85.
  • Schentag JJ, Ziemniak JA, Greco JM, Rainstein M, Buckley RJ. Mental confusion in a patient treated with metronidazole- -a concentration-related effect? Pharmacotherapy. 1982; 2(6): 384-7.
  • Agarwal A, Kanekar S. Thamburaj K. Metronidazole-induced cerebellar toxicity. Neurology international. 2016;8(1): 63-5.
  • Sorensen C, Karlsson W, Amin F, Lindelof M. Metronidazoleinduced encephalopathy: a systematic review. Journal of Neurology, 2018; 267: 1-13.

Year 2024, Volume: 6 Issue: 3, 59 - 60, 31.12.2024
https://doi.org/10.51262/ejtox.1585902
https://izlik.org/JA52KG92ET

Abstract

Project Number

no

References

  • Revollo JY, Lowder JC, Pierce AS, Twilla JD. Urine Discoloration Associated With Metronidazole: A Rare Occurrence. Journal of Pharmacy Technology. 2014; 30(2): 54–6.
  • Özel Ö, Cesur S, Ataman Hatipoğlu Ç, Altun Demircan Ş, Kaya Kılıç E, Kınıklı S, et al. Metronidazol tedavisine bağlı olarak lökopeni ve trombositopeni gelişen akut gastroenterit olgusu. Turk J Clin Lab. 2017; 8(1): 32-4.
  • Gussago S, Bastone CP, Celio D, Arigoni M, Quarenghi MC. Metronidazole and Peripheral Neuropathy: A Report of Two Cases of (Unusual) Side Effects. Cureus. 2022; 31;14(10):e30889.
  • Altunışık E, Eke Kurt ŞZ. Transient Encephalopathy with A Single Dose of Oral Metronidazole: A Case Report. Turk J Neurol. 2021; 27: 82-4.
  • Khandheria M, Snook E, Thomas C. Psychotic episode secondary to metronidazole use. General Hospital Psychiatry. 2014; 36: 231.e3–231.e4.
  • Testa A, Giannuzzi R, Sollazzo F, Petrongolo L, Bernardini L, Dain S. Psychiatric emergencies (part II): psychiatric disorders coexisting with organic diseases. Eur Rev Med Pharmacol Sci. 2013; 17 (1): 65-85.
  • Schentag JJ, Ziemniak JA, Greco JM, Rainstein M, Buckley RJ. Mental confusion in a patient treated with metronidazole- -a concentration-related effect? Pharmacotherapy. 1982; 2(6): 384-7.
  • Agarwal A, Kanekar S. Thamburaj K. Metronidazole-induced cerebellar toxicity. Neurology international. 2016;8(1): 63-5.
  • Sorensen C, Karlsson W, Amin F, Lindelof M. Metronidazoleinduced encephalopathy: a systematic review. Journal of Neurology, 2018; 267: 1-13.
There are 9 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Case Report
Authors

Sumeyra Dag 0009-0001-4371-8499

Melike Efnan Binici 0009-0000-9047-2439

Duhan Kanmaz 0000-0003-4507-4698

Bahadir Taslidere 0000-0002-5920-8127

Project Number no
Submission Date November 15, 2024
Acceptance Date December 18, 2024
Publication Date December 31, 2024
DOI https://doi.org/10.51262/ejtox.1585902
IZ https://izlik.org/JA52KG92ET
Published in Issue Year 2024 Volume: 6 Issue: 3

Cite

APA Dag, S., Binici, M. E., Kanmaz, D., & Taslidere, B. (2024). Auditory Hallucination Associated With Metronidazole: A Case Report. Eurasian Journal of Toxicology, 6(3), 59-60. https://doi.org/10.51262/ejtox.1585902
AMA 1.Dag S, Binici ME, Kanmaz D, Taslidere B. Auditory Hallucination Associated With Metronidazole: A Case Report. Eurasian J Tox. 2024;6(3):59-60. doi:10.51262/ejtox.1585902
Chicago Dag, Sumeyra, Melike Efnan Binici, Duhan Kanmaz, and Bahadir Taslidere. 2024. “Auditory Hallucination Associated With Metronidazole: A Case Report”. Eurasian Journal of Toxicology 6 (3): 59-60. https://doi.org/10.51262/ejtox.1585902.
EndNote Dag S, Binici ME, Kanmaz D, Taslidere B (December 1, 2024) Auditory Hallucination Associated With Metronidazole: A Case Report. Eurasian Journal of Toxicology 6 3 59–60.
IEEE [1]S. Dag, M. E. Binici, D. Kanmaz, and B. Taslidere, “Auditory Hallucination Associated With Metronidazole: A Case Report”, Eurasian J Tox, vol. 6, no. 3, pp. 59–60, Dec. 2024, doi: 10.51262/ejtox.1585902.
ISNAD Dag, Sumeyra - Binici, Melike Efnan - Kanmaz, Duhan - Taslidere, Bahadir. “Auditory Hallucination Associated With Metronidazole: A Case Report”. Eurasian Journal of Toxicology 6/3 (December 1, 2024): 59-60. https://doi.org/10.51262/ejtox.1585902.
JAMA 1.Dag S, Binici ME, Kanmaz D, Taslidere B. Auditory Hallucination Associated With Metronidazole: A Case Report. Eurasian J Tox. 2024;6:59–60.
MLA Dag, Sumeyra, et al. “Auditory Hallucination Associated With Metronidazole: A Case Report”. Eurasian Journal of Toxicology, vol. 6, no. 3, Dec. 2024, pp. 59-60, doi:10.51262/ejtox.1585902.
Vancouver 1.Sumeyra Dag, Melike Efnan Binici, Duhan Kanmaz, Bahadir Taslidere. Auditory Hallucination Associated With Metronidazole: A Case Report. Eurasian J Tox. 2024 Dec. 1;6(3):59-60. doi:10.51262/ejtox.1585902