Case Report
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Kontrolsüz kullanılan bir insektisit olan alüminyum fosfit zehirlenmesine bağlı bebek ölümü: Olgu sunumu

Year 2019, Volume: 1 Issue: 1, 33 - 36, 01.03.2019

Abstract

Fosfin gazı difüzyon kapasitesinin yüksek olmasından
ve tarımsal ürünlerde kalıntı bırakmamasından dolayı rodentisit ve insektisit
olarak sıklıkla kullanılan bir gazdır. Bu gaz oldukça toksik olduğundan
preparat olarak kile emdirilmiş alüminyum fosfit tabletleri olarak ülkemizde
bulunmakta, bu tabletler havadaki nem ya da mide de hidroklorik asit ile
karşılaştığında fosfin gazı ortaya çıkmaktadır. Maruz kalınan doza bağımlı
olarak alüminyum fosfit intoksikasyonlarında mortalite oranları %40-80 olarak
belirtilmiştir. Bu kadar tehlikeli olan alüminyum fosfit tabletlerinin
temininde ülkemizde herhangi bir kontrol mekanizması olmadığı gibi bu
tabletlerin kullanımı sırasında oluşabilecek ciddi durumlar hakkında herhangi
bir bilgilendirme de yapılmamaktadır.



              Ailesi
biber-patlıcan kurutuculuğu yapan 2 aylık bebeğin inhalasyon yoluyla fosfin
gazına maruz kaldığı, kusma ve morarma şikayetleriyle hastaneye kaldırıldığı ve
24 saat içerisinde hayatını kaybettiği bildirilmiştir. Bilinçsiz kullanılan
alüminyum fosfite bağlı gelişen intoksikasyon sonucu hayatını kaybeden olgumuzu
erken tanı-tedavinin ve toksikolojik inceleme için örnek alımının önemi vurgulanarak
adli ve tıbbi belgeler eşliğinde sunuldu

References

  • German Jørgensen JR, Rössel PR. Poisoning with aluminum phosphide can be life-threatening for patients as well as health professionals. Ugeskr Laeger. 2013; 175: 1706-7.
  • Mehrpour O, Singh S. Rice tablet poisoning: a major concern in Iranian population. Hum Exp Toxicol. 2010; 29: 701-2.
  • Singh D, Jit I, Tyagi S. Changing trends in acute poisoning in Chandigarh zone: a 25-year autopsy experience from a tertiary care hospital in northern India. Am J Forensic Med Pathol. 1999; 20: 203-10.
  • Siwach SB, Gupta A. The profile of acute poisonings in Harayana Rohtak Study. J Assoc Physicians India. 1995; 43: 756-9.
  • Chugh SN, Arora V, Sharma A, Chugh K. Free radical scavengers & lipid peroxidation in acute aluminium phosphide poisoning. Indian J Med Res. 1996; 104: 190-3.
  • Solgi R, Abdollahi M. Proposing an antidote for poisonous phosphine in view of mitochondrial electrochemistry facts. J Med Hypotheses Ideas. 2012; 6: 32-4.
  • Bogle RG, Theron P, Brooks P, Dargan PI, Redhead J. Aluminium phosphide poisoning. Emerg Med J. 2006; 23: e3.
  • Tolunay O, Çelik T, Yücel G, Özdemir U, Atmış A, Sucu A, Çelik Ü. Nadir ama Ölümcül Olabilen Bir Zehirlenme: Alüminyum Fosfit Zehirlenmesi. J Pediatr Emerg Intensive Care Med. 2017; 4: 27-9
  • Gurjar M, Baronia AK, Azim A, Sharma K. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011; 4: 378-84.
  • Etemadi-Aleagha A, Akhgari M, Iravani FS. Aluminum Phosphide Poisoning-Related Deaths in Tehran, İran, 2006 to 2013. Medicine (Baltimore). 2015; 94: 1637.
  • Ekinci F, Dinçer R, Horoz ÖÖ, Kendir ÖT, Petmezci E, Tolunay İ, Yılmaz HL. Alüminyum Fosfit Zehirlenmesi: İki Çocuk Olgu ve İki Ayrı Klinik Sonuç. J Pediatr Emerg Intensive Care Med. 2017; 4: 72-6
  • Demir U, Hekimoğlu Y, Aşırdizer M, Etli Y, Kartal E, Gümüş O. A case who died due to the suicidal intake of aluminum phosphide. Cumhuriyet Medical Journal. 2017; 39: 458-65.
  • Karadeniz H, Boz H, Ketenci HÇ. Sıra Dışı Bir Kaza ile Meydana Gelen ve Ölümle Sonuçlanan Alüminyum Fosfit Zehirlenmesi: Olgu Sunumu. Adli Tıp Bülteni, 2018; 23(2): 129-32

Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report

Year 2019, Volume: 1 Issue: 1, 33 - 36, 01.03.2019

Abstract

Phosphine gas is a
gas that is frequently used as rodenticide and insecticide due to its high
diffusion capacity and the absence of residues in agricultural products. Since
this gas is highly toxic, it is found in our country as aluminum phosphite
tablets impregnated with clay, these tablets emit phosphine gas when they meet
with the moisture in the air or gastric hydrochloric acid. Mortality rates in
aluminum phosphite intoxications are 40-80% depending on the exposure dose.
There is no control mechanism in the supply of aluminum phosphide tablets which
are so dangerous and no information is given about the serious conditions that
may occur during the use of these tablets.



A 2 month old baby,
whose family practiced drying pepper-eggplant, was reported to have been
exposed to phosphine gas by inhalation, admitted to hospital with vomiting and
cyanosis and lost his life within 24 hours. We present our case, who lost his
life due to erroneous usage of aluminum phosphite, with additional emphasis on
early diagnosis, treatment and gathering sample for toxicologic analysis, with
corresponding forensic and medical documents.

References

  • German Jørgensen JR, Rössel PR. Poisoning with aluminum phosphide can be life-threatening for patients as well as health professionals. Ugeskr Laeger. 2013; 175: 1706-7.
  • Mehrpour O, Singh S. Rice tablet poisoning: a major concern in Iranian population. Hum Exp Toxicol. 2010; 29: 701-2.
  • Singh D, Jit I, Tyagi S. Changing trends in acute poisoning in Chandigarh zone: a 25-year autopsy experience from a tertiary care hospital in northern India. Am J Forensic Med Pathol. 1999; 20: 203-10.
  • Siwach SB, Gupta A. The profile of acute poisonings in Harayana Rohtak Study. J Assoc Physicians India. 1995; 43: 756-9.
  • Chugh SN, Arora V, Sharma A, Chugh K. Free radical scavengers & lipid peroxidation in acute aluminium phosphide poisoning. Indian J Med Res. 1996; 104: 190-3.
  • Solgi R, Abdollahi M. Proposing an antidote for poisonous phosphine in view of mitochondrial electrochemistry facts. J Med Hypotheses Ideas. 2012; 6: 32-4.
  • Bogle RG, Theron P, Brooks P, Dargan PI, Redhead J. Aluminium phosphide poisoning. Emerg Med J. 2006; 23: e3.
  • Tolunay O, Çelik T, Yücel G, Özdemir U, Atmış A, Sucu A, Çelik Ü. Nadir ama Ölümcül Olabilen Bir Zehirlenme: Alüminyum Fosfit Zehirlenmesi. J Pediatr Emerg Intensive Care Med. 2017; 4: 27-9
  • Gurjar M, Baronia AK, Azim A, Sharma K. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011; 4: 378-84.
  • Etemadi-Aleagha A, Akhgari M, Iravani FS. Aluminum Phosphide Poisoning-Related Deaths in Tehran, İran, 2006 to 2013. Medicine (Baltimore). 2015; 94: 1637.
  • Ekinci F, Dinçer R, Horoz ÖÖ, Kendir ÖT, Petmezci E, Tolunay İ, Yılmaz HL. Alüminyum Fosfit Zehirlenmesi: İki Çocuk Olgu ve İki Ayrı Klinik Sonuç. J Pediatr Emerg Intensive Care Med. 2017; 4: 72-6
  • Demir U, Hekimoğlu Y, Aşırdizer M, Etli Y, Kartal E, Gümüş O. A case who died due to the suicidal intake of aluminum phosphide. Cumhuriyet Medical Journal. 2017; 39: 458-65.
  • Karadeniz H, Boz H, Ketenci HÇ. Sıra Dışı Bir Kaza ile Meydana Gelen ve Ölümle Sonuçlanan Alüminyum Fosfit Zehirlenmesi: Olgu Sunumu. Adli Tıp Bülteni, 2018; 23(2): 129-32
There are 13 citations in total.

Details

Primary Language English
Subjects Toxicology
Journal Section Case Reports
Authors

Cem Terece

Veysel Osman Soğukpınar This is me

Nazım Özdemir This is me

Sinem Polat This is me

Publication Date March 1, 2019
Submission Date January 19, 2019
Published in Issue Year 2019 Volume: 1 Issue: 1

Cite

APA Terece, C., Soğukpınar, V. O., Özdemir, N., Polat, S. (2019). Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report. Eurasian Journal of Toxicology, 1(1), 33-36.
AMA Terece C, Soğukpınar VO, Özdemir N, Polat S. Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report. Eurasian J Tox. March 2019;1(1):33-36.
Chicago Terece, Cem, Veysel Osman Soğukpınar, Nazım Özdemir, and Sinem Polat. “Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report”. Eurasian Journal of Toxicology 1, no. 1 (March 2019): 33-36.
EndNote Terece C, Soğukpınar VO, Özdemir N, Polat S (March 1, 2019) Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report. Eurasian Journal of Toxicology 1 1 33–36.
IEEE C. Terece, V. O. Soğukpınar, N. Özdemir, and S. Polat, “Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report”, Eurasian J Tox, vol. 1, no. 1, pp. 33–36, 2019.
ISNAD Terece, Cem et al. “Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report”. Eurasian Journal of Toxicology 1/1 (March 2019), 33-36.
JAMA Terece C, Soğukpınar VO, Özdemir N, Polat S. Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report. Eurasian J Tox. 2019;1:33–36.
MLA Terece, Cem et al. “Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report”. Eurasian Journal of Toxicology, vol. 1, no. 1, 2019, pp. 33-36.
Vancouver Terece C, Soğukpınar VO, Özdemir N, Polat S. Infant Death Due to Aluminum Phosphide Intoxication, An Uncontrolled Insecticide Used : Case Report. Eurasian J Tox. 2019;1(1):33-6.

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