The Effects of Magnesium Levels on Prognosis in Organophosphate Poisoning

Year 2019, Volume: 1 Issue: 1, 7 - 10, 01.03.2019

İsmail Aktaş Ramazan Köylü Öznur Köylü Başar Cander

Abstract

Objectives: To investigate the predictive value of magnesium, neutrophil/lymphocyte ratios (NLR) in determining the severity of morbidity and mortality

in patients with organophosphate poisoning (OP) admitted to the emergency department.

Materials ad Methods: This study was conducted retrospectively by scanning the medical recordings of patients aged over 18 years who were admitted

to our emergency department with OP between 2010 and 2015. The demographic characteristics, medical history, laboratory findings, and Glasgow Coma

Scale (GCS) scores of the patients were recorded.

Results: The data of 153 patients, 91 males and 62 females, were evaluated. There was no significant correlation between the changes in magnesium,

hemoglobin, hematocrit, leukocytosis, platelets, potassium, calcium, glucose, alanine aminotransferase (ALT), troponin, and mortality in patients with OP

(p>0.05). There was a significant relationship between the increase in lactate dehydrogenase (LDH) (p=0.004), low lymphocyte count (p=0.003), decreased

cholinesterase (p=0.001), higher (NLR) (p=0.002), GCS (p<0.001), mechanical ventilator (MV) requirement (p<0.001), age (P=0.009), vasopressor treatment

(p<0.001), and mortality.

Conclusion: No significant relationship determined between magnesium levels and prognosis. Low lymphocyte count, decreased cholinesterase, increased

LDH and NLR in patients with OP were significantly correlated with mortality. Increased NLR ratio, one of the parameters in routine hemograms, may give

information to physicians about the long-term follow-up of such patients with OP.

Keywords

Emergency, Organophosphate, Magnesium, Neutrophil lymphocyte ratio

References

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