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Year 2020, Volume: 2 Issue: 2, 50 - 52, 11.11.2020

Abstract

References

  • References:1. Batalis NI, Harley RA, Schandl CA. Verapamil toxicity an unusual case report and review of the literature. Am J Forensic Med Pathol 2007; 28: 137– 40.
  • 2. Tuka V, Ricarova B, Janota T, Malik J, Kortlikova E. Surprisingly delayed escalation of severe verapamil poisoning. Eur J Emerg Med 2009;1 6: 100–2
  • 3. Tebbutt S, Harvey M, Nicholson T, Cave G: Intralipid prolongs survival in a rat model of verapamil toxicity. Acad Emerg Med 2006, 13: 134-139.
  • 4. Perez E, Bania TC, Medlej K, Chu J: Determining the optimal dose of intravenous fat emulsion for the treatment of severe verapamil toxicity in a rodent model. Acad Emerg Med 2008, 15: 1284-1289
  • 5. Weinberg GL, VadeBoncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ: Pretreatment or resuscitation with a lipid infusion shifts the doseresponse to bupivacaine-induced asystole in rats. Anesthesiology 1998,88:1071-1075.
  • 6. Weinberg G: Lipid rescue resuscitation from local anaesthetic cardiac toxicity. Toxicol Rev 2006, 25: 139-145.
  • 7. Sirianni AJ, Osterhoudt KC, Calello DP, Muller AA, Waterhouse MR, Goodkin MB, Weinberg GL, Henretig FM: Use of lipid emulsion in the resuscitation of a patient with prolonged cardiovascular collapse after overdose of bupropion and lamotrigine. Ann Emerg Med 2008, 51: 412-415
  • 8. Patel NP, Pugh ME, Goldberg S, Eiger G. Hyperinsulinemic euglycemia therapy for verapamil poisoning: case report. Am J CritCare 2007; 16: 520-8.
  • 9. Sporer KA, Manning JJ. Massive ingestion of sustained-release verapamil with a concretion and bowel infarction. Ann Emerg Med 1993; 22: 603–5.
  • 10. Kol İÖ, Polat S, Özkan F, Kaygusuz K, Gönüllü M. Yavaş Salınımlı Verapamil intoksikasyonu. Türkiye Klinikleri J Med Sci 2005; 25: 749–52.
  • 11. Harvey M, Cave G. Intralipid outperforms sodium bicarbonate in a rabbit model of clomipramine toxicity. Ann Emerg Med 2007; 49(2): 178-85.
  • 12. Hendron D, Menagh G, Sandilands EA, Scullion D. Tricyclic antidepressant overdose in a toddler treated with intravenous lipid emulsion. Pediatrics 2011; 128(6): 1628-32.
  • 13. Levine M, Brooks DE, Franken A, Graham R. Delayed-onset seizure and cardiac arrest after amitriptyline overdose, treated with intravenous lipid emulsion therapy. Pediatrics 2012; 130(2): 432-8
  • 14. American College of Medical Toxicology. ACMT position statement: interim guidance forthe use of lipid resuscitation therapy. J Med Toxicol 2011;7(1):81-2.
  • 15. Fettiplace MR, Akpa BS, Rubinstein I, Weinberg G. Confusion about infusion: rational volüme limits for intravenous lipid emulsion during treatment of oral overdoses. Ann Emerg Med 2015; 66(2): 185-8

Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication

Year 2020, Volume: 2 Issue: 2, 50 - 52, 11.11.2020

Abstract

The use of intravenous lipid emulsion therapy (ILE) as an antidote in
toxicology has become an increasingly popular in recent years. In pediatric age
group, the reported number of cases treated with ILE is very low. Successful
results have been reported with ILE therapy in tricyclic antidepressant,
verapamil, and beta blocker poisonings in cases that are not responsive to the standard
treatment methods. In this article, we present a clinical and laboratory
finding of a case that did not respond to standard treatment and was
successfully treated with ILE therapy. 

References

  • References:1. Batalis NI, Harley RA, Schandl CA. Verapamil toxicity an unusual case report and review of the literature. Am J Forensic Med Pathol 2007; 28: 137– 40.
  • 2. Tuka V, Ricarova B, Janota T, Malik J, Kortlikova E. Surprisingly delayed escalation of severe verapamil poisoning. Eur J Emerg Med 2009;1 6: 100–2
  • 3. Tebbutt S, Harvey M, Nicholson T, Cave G: Intralipid prolongs survival in a rat model of verapamil toxicity. Acad Emerg Med 2006, 13: 134-139.
  • 4. Perez E, Bania TC, Medlej K, Chu J: Determining the optimal dose of intravenous fat emulsion for the treatment of severe verapamil toxicity in a rodent model. Acad Emerg Med 2008, 15: 1284-1289
  • 5. Weinberg GL, VadeBoncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ: Pretreatment or resuscitation with a lipid infusion shifts the doseresponse to bupivacaine-induced asystole in rats. Anesthesiology 1998,88:1071-1075.
  • 6. Weinberg G: Lipid rescue resuscitation from local anaesthetic cardiac toxicity. Toxicol Rev 2006, 25: 139-145.
  • 7. Sirianni AJ, Osterhoudt KC, Calello DP, Muller AA, Waterhouse MR, Goodkin MB, Weinberg GL, Henretig FM: Use of lipid emulsion in the resuscitation of a patient with prolonged cardiovascular collapse after overdose of bupropion and lamotrigine. Ann Emerg Med 2008, 51: 412-415
  • 8. Patel NP, Pugh ME, Goldberg S, Eiger G. Hyperinsulinemic euglycemia therapy for verapamil poisoning: case report. Am J CritCare 2007; 16: 520-8.
  • 9. Sporer KA, Manning JJ. Massive ingestion of sustained-release verapamil with a concretion and bowel infarction. Ann Emerg Med 1993; 22: 603–5.
  • 10. Kol İÖ, Polat S, Özkan F, Kaygusuz K, Gönüllü M. Yavaş Salınımlı Verapamil intoksikasyonu. Türkiye Klinikleri J Med Sci 2005; 25: 749–52.
  • 11. Harvey M, Cave G. Intralipid outperforms sodium bicarbonate in a rabbit model of clomipramine toxicity. Ann Emerg Med 2007; 49(2): 178-85.
  • 12. Hendron D, Menagh G, Sandilands EA, Scullion D. Tricyclic antidepressant overdose in a toddler treated with intravenous lipid emulsion. Pediatrics 2011; 128(6): 1628-32.
  • 13. Levine M, Brooks DE, Franken A, Graham R. Delayed-onset seizure and cardiac arrest after amitriptyline overdose, treated with intravenous lipid emulsion therapy. Pediatrics 2012; 130(2): 432-8
  • 14. American College of Medical Toxicology. ACMT position statement: interim guidance forthe use of lipid resuscitation therapy. J Med Toxicol 2011;7(1):81-2.
  • 15. Fettiplace MR, Akpa BS, Rubinstein I, Weinberg G. Confusion about infusion: rational volüme limits for intravenous lipid emulsion during treatment of oral overdoses. Ann Emerg Med 2015; 66(2): 185-8
There are 15 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Case Reports
Authors

Evrim Gül 0000-0001-9049-5446

M. Yusuf Sarı This is me

Publication Date November 11, 2020
Submission Date May 24, 2019
Published in Issue Year 2020 Volume: 2 Issue: 2

Cite

APA Gül, E., & Sarı, M. Y. (2020). Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication. Eurasian Journal of Toxicology, 2(2), 50-52.
AMA Gül E, Sarı MY. Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication. Eurasian J Tox. November 2020;2(2):50-52.
Chicago Gül, Evrim, and M. Yusuf Sarı. “Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication”. Eurasian Journal of Toxicology 2, no. 2 (November 2020): 50-52.
EndNote Gül E, Sarı MY (November 1, 2020) Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication. Eurasian Journal of Toxicology 2 2 50–52.
IEEE E. Gül and M. Y. Sarı, “Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication”, Eurasian J Tox, vol. 2, no. 2, pp. 50–52, 2020.
ISNAD Gül, Evrim - Sarı, M. Yusuf. “Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication”. Eurasian Journal of Toxicology 2/2 (November 2020), 50-52.
JAMA Gül E, Sarı MY. Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication. Eurasian J Tox. 2020;2:50–52.
MLA Gül, Evrim and M. Yusuf Sarı. “Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication”. Eurasian Journal of Toxicology, vol. 2, no. 2, 2020, pp. 50-52.
Vancouver Gül E, Sarı MY. Intravenous Lipid Emulsıon Treatment In The Verapamil Intoxication. Eurasian J Tox. 2020;2(2):50-2.

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