Metotreksat Kullanıma Bağlı Pansitopeni

Year 2020, Volume: 2 Issue: 3, 76 - 77, 05.12.2020

Fatih Güneysu Ayhan Sarıtaş Ensar Durmuş Semih Güneysu

Abstract

Methotrexate;
Folic acid analogue and antagonist, commonly used immunosuppressive agent. It
is used as long-term and low-dose in patients with rheumatoid arthritis.
Although anemia, thrombocytopenia or leukopenia are rare in hematological
toxicity of low-dose MTX therapy, pancytopenia is rarely encountered. Herein,
we aimed to present a case with pancytopenia due to MTX use.

Keywords

Pancytopeni, methotrexate, emergency

Metotreksat Kullanıma Bağlı Pansitopeni

Abstract

Metotreksat; folik asit analoğu ve antagonisti olup, sık kullanılan immunsupresif ajandır. Romatoid artrit hastalarında uzun süreli ve düşük dozlu olarak kullanılmaktadır.
Düşük doz MTX tedavisinin hematolojik toksisitesinde anemi, trombositopeni veya lökopeni durumları az görülmesine rağmen pansitopeni
çok daha nadir olarak karşımıza çıkmaktadır. Biz burada, MTX kullanımına bağlı pansitopeni gelişen olguyu sunmayı amaçladık.

Keywords

pansitopeni, metotreksat, acil

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