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Year 2016, Volume: 6 Issue: 1, 12 - 14, 30.04.2016

Abstract

References

  • 1. de Miguel Martinez I, Macias AR. Serous otitis media in children: implication of Alloiococcus otitidis. Otol Neurotol 2008; 29:526–30.
  • 2. Holder RC, Kirse DJ, Evans AK, et al. One third of middle ear effusions from children undergoing tympanostomy tube placement had multiple bacterial pathogens. BMC Pediatr 2012;12: 87.
  • 3. Peitersen E. The natural history of Bell’s palsy. Am J Otol 1982; 4:107–11.
  • 4. Yilmaz M, Tarakcioglu M, Bayazit N, Bayazit YA, Namiduru M, Kanlikama M. Serum cytokine levels in Bell’s palsy. J Neurol Sci 2002;197:69–72.
  • 5. Somuk BT, Soyal›ç H, Koc S, Gürbüzler L, Do¤ru S, Eyibilen A. Mean platelet volume as an inflammatory marker of chronic otitis media with effusion. Int J Pediatr Otorhinolaryngol 2014; 78:1958–60.
  • 6. Rushton HC, Tong MC, Yue V, Wormald PJ, van Hasselt CA. Prevalence of otitis media with effusion in multicultural schools in Hong Kong. J Laryngol Otol 1997;111:804–6.
  • 7. Holmquist J, Al Fadala S, Qattan Y. Prevalence of secretory otitis media among school children in Kuwait. J Laryngol Otol 1987;101:116–9.
  • 8. Erdivanli OC, Coskun ZO, Kazikdas KC, Demirci M. Prevalence of otitis media with effusion among primary school children in Eastern Black Sea, in Turkey and the effect of smoking in the development of otitis media with effusion. Indian J Otolaryngol Head Neck Surg 2012;64:17–21.
  • 9. Yellon RF, Leonard G, Marucha PT, et al. Characterization of cytokines present in middle ear effusions. Laryngoscope 1991;101:165–9.
  • 10. Smirnova MG, Kiselev SL, Gnuchev NV, Birchall JP, Pearson JP. Role of the pro-inflammatory cytokines tumor necrosis factor- alpha, interleukin-1 beta, interleukin-6 and interleukin-8 in the pathogenesis of the otitis media with effusion. Eur Cytokine Netw 2002;13:161–72.
  • 11. Bhat T, Teli S, Rijal J, et al. Neutrophil to lymphocyte ratio and cardiovascular diseases: a review. Expert Rev Cardiovasc Ther 2013;11:55–9.
  • 12. Ulu S, Ulu MS, Bucak A, Ahsen A, Yucedag F, Aycicek A. Neutrophil-to-lymphocyte ratio as a new, quick, and reliable indicator for predicting diagnosis and prognosis of idiopathic sudden sensorineural hearing loss. Otol Neurotol 2013;34:1400–4.
  • 13. Azab B, Shah N, Akerman M, McGinn Jr JT. Value of platelet/lymphocyte ratio as a predictor of all-cause mortality after non-ST-elevation myocardial infarction. J Thromb Thrombolysis 2012;34:326–34.

Kronik effüzyonlu otit tanısında yeni tanısal belirteçler: Nötrofil lenfosit oranı ve trombosit lenfosit oranı

Year 2016, Volume: 6 Issue: 1, 12 - 14, 30.04.2016

Abstract

Objective: Inflammation has an important place in chronic otitis media with effusion (COME) etiology. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are simple and cheap tests that show inflammation and can be calculated by all physicians. In our study, we aimed to investigate the relationship between COME and NLR and PLR parameters.

Methods: The study was performed with the pediatric patient group consisting of 77 patients who got diagnosis of COME and the control group consisting of 62 healthy children whose age, gender and demographical characteristics were concordant with the patient group. The patient and control groups were compared statistically in terms of NLR and PLR values.

Results: Mean neutrophil to lymphocyte ratio value was found as 1.43±0.54 in the patient group and as 1.16±0.51 in the control group (p<0.001). Mean PLR value was found as 113.78±35.78 in the patient group and as 103.61±32.32 in the control group (p= 0.084).

Conclusion: Neutrophil to lymphocyte ratio and PLR values were high in COME. It was shown for the first time that NLR can be used as a diagnostic parameter in children with COME.

References

  • 1. de Miguel Martinez I, Macias AR. Serous otitis media in children: implication of Alloiococcus otitidis. Otol Neurotol 2008; 29:526–30.
  • 2. Holder RC, Kirse DJ, Evans AK, et al. One third of middle ear effusions from children undergoing tympanostomy tube placement had multiple bacterial pathogens. BMC Pediatr 2012;12: 87.
  • 3. Peitersen E. The natural history of Bell’s palsy. Am J Otol 1982; 4:107–11.
  • 4. Yilmaz M, Tarakcioglu M, Bayazit N, Bayazit YA, Namiduru M, Kanlikama M. Serum cytokine levels in Bell’s palsy. J Neurol Sci 2002;197:69–72.
  • 5. Somuk BT, Soyal›ç H, Koc S, Gürbüzler L, Do¤ru S, Eyibilen A. Mean platelet volume as an inflammatory marker of chronic otitis media with effusion. Int J Pediatr Otorhinolaryngol 2014; 78:1958–60.
  • 6. Rushton HC, Tong MC, Yue V, Wormald PJ, van Hasselt CA. Prevalence of otitis media with effusion in multicultural schools in Hong Kong. J Laryngol Otol 1997;111:804–6.
  • 7. Holmquist J, Al Fadala S, Qattan Y. Prevalence of secretory otitis media among school children in Kuwait. J Laryngol Otol 1987;101:116–9.
  • 8. Erdivanli OC, Coskun ZO, Kazikdas KC, Demirci M. Prevalence of otitis media with effusion among primary school children in Eastern Black Sea, in Turkey and the effect of smoking in the development of otitis media with effusion. Indian J Otolaryngol Head Neck Surg 2012;64:17–21.
  • 9. Yellon RF, Leonard G, Marucha PT, et al. Characterization of cytokines present in middle ear effusions. Laryngoscope 1991;101:165–9.
  • 10. Smirnova MG, Kiselev SL, Gnuchev NV, Birchall JP, Pearson JP. Role of the pro-inflammatory cytokines tumor necrosis factor- alpha, interleukin-1 beta, interleukin-6 and interleukin-8 in the pathogenesis of the otitis media with effusion. Eur Cytokine Netw 2002;13:161–72.
  • 11. Bhat T, Teli S, Rijal J, et al. Neutrophil to lymphocyte ratio and cardiovascular diseases: a review. Expert Rev Cardiovasc Ther 2013;11:55–9.
  • 12. Ulu S, Ulu MS, Bucak A, Ahsen A, Yucedag F, Aycicek A. Neutrophil-to-lymphocyte ratio as a new, quick, and reliable indicator for predicting diagnosis and prognosis of idiopathic sudden sensorineural hearing loss. Otol Neurotol 2013;34:1400–4.
  • 13. Azab B, Shah N, Akerman M, McGinn Jr JT. Value of platelet/lymphocyte ratio as a predictor of all-cause mortality after non-ST-elevation myocardial infarction. J Thromb Thrombolysis 2012;34:326–34.
There are 13 citations in total.

Details

Subjects Health Care Administration
Journal Section Articles
Authors

Doğan Atan

Emre Apaydın This is me

Kürşat Murat Özcan This is me

Hüseyin Dere This is me

Publication Date April 30, 2016
Submission Date July 21, 2017
Published in Issue Year 2016 Volume: 6 Issue: 1

Cite

APA Atan, D., Apaydın, E., Özcan, K. M., Dere, H. (2016). Kronik effüzyonlu otit tanısında yeni tanısal belirteçler: Nötrofil lenfosit oranı ve trombosit lenfosit oranı. ENT Updates, 6(1), 12-14.
AMA Atan D, Apaydın E, Özcan KM, Dere H. Kronik effüzyonlu otit tanısında yeni tanısal belirteçler: Nötrofil lenfosit oranı ve trombosit lenfosit oranı. ENT Updates. April 2016;6(1):12-14.
Chicago Atan, Doğan, Emre Apaydın, Kürşat Murat Özcan, and Hüseyin Dere. “Kronik effüzyonlu Otit tanısında Yeni tanısal belirteçler: Nötrofil Lenfosit Oranı Ve Trombosit Lenfosit Oranı”. ENT Updates 6, no. 1 (April 2016): 12-14.
EndNote Atan D, Apaydın E, Özcan KM, Dere H (April 1, 2016) Kronik effüzyonlu otit tanısında yeni tanısal belirteçler: Nötrofil lenfosit oranı ve trombosit lenfosit oranı. ENT Updates 6 1 12–14.
IEEE D. Atan, E. Apaydın, K. M. Özcan, and H. Dere, “Kronik effüzyonlu otit tanısında yeni tanısal belirteçler: Nötrofil lenfosit oranı ve trombosit lenfosit oranı”, ENT Updates, vol. 6, no. 1, pp. 12–14, 2016.
ISNAD Atan, Doğan et al. “Kronik effüzyonlu Otit tanısında Yeni tanısal belirteçler: Nötrofil Lenfosit Oranı Ve Trombosit Lenfosit Oranı”. ENT Updates 6/1 (April 2016), 12-14.
JAMA Atan D, Apaydın E, Özcan KM, Dere H. Kronik effüzyonlu otit tanısında yeni tanısal belirteçler: Nötrofil lenfosit oranı ve trombosit lenfosit oranı. ENT Updates. 2016;6:12–14.
MLA Atan, Doğan et al. “Kronik effüzyonlu Otit tanısında Yeni tanısal belirteçler: Nötrofil Lenfosit Oranı Ve Trombosit Lenfosit Oranı”. ENT Updates, vol. 6, no. 1, 2016, pp. 12-14.
Vancouver Atan D, Apaydın E, Özcan KM, Dere H. Kronik effüzyonlu otit tanısında yeni tanısal belirteçler: Nötrofil lenfosit oranı ve trombosit lenfosit oranı. ENT Updates. 2016;6(1):12-4.