The investigation of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in children with pathological cervical lymphadenopathy

Year 2017, Volume: 7 Issue: 2, 99 - 103, 30.09.2017

Saime Güzelsoy Sağıroğlu Selman Sarıca Nagihan Bilal İsrafil Orhan Ayşegül Erdoğan Metin Kılıç

Abstract

Objective: To reveal whether if neutrophil
to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) rates
are useful or not in children followed-up due to pathological cervical
lymphadenopathy (LAP) of unknown etiology who have a normal hematologic
examination.




Methods: A
total of 100 children admitted to the otorhinolaryngology clinic between
2014 and 2017 with the complaint of swelling in the neck without any
etiology revealed on examination and established with the diagnosis of
idiopathic pathological LAP were retrospectively included in the study.
The control group consisted of 100 children who did not have any
infectious condition and could be considered healthy in terms of
examination and laboratory findings. Patients' and the control group's
age, gender, clinical history, disease course and examination findings
were screened from the patients' records in the clinic.




Results:
Mean white blood cell and lymphocyte count parameters in the patient
group were higher than the control group, and the difference was
statistically significant (p=0.008 and p=0.001, respectively). In the
patient group, mean NLR and PLR values were significantly lower than the
control group (p=0.009 and p=0.020, respectively).




Conclusion: NLR
and PLR rates may be well correlated with inflammation in children
followed-up due to pathologic cervical LAP with unknown etiology.

Keywords

Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, lymphadenopathy

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