Therapeutic efficacy of salvage hyperbaric oxygen therapy in sudden sensorineural hearing loss after failure of steroids

Year 2017, Volume: 7 Issue: 3, 120 - 125, 28.11.2017

Abdulkadir İmre İbrahim Aladağ Ercan Pınar Hale Aslan Rıdvan Duran Mustafa Yazır

Abstract

Objective: The aim of this study was to
evaluate the efficacy of hyperbaric oxygen (HBO) therapy as salvage
therapy in patients with idiopathic sudden sensorineural hearing loss
(ISSNHL) after failure of systemic therapy.




Methods:
Forty-eight consecutive patients with refractory ISSNHL were enrolled
retrospectively. All patients were given systemic steroid therapy by
tapered doses. In addition, forty-one patients received intratympanic
dexamethasone injection. Hearing outcomes were determined by recovery
rate according to Siegel's criteria and hearing gains in pure-tone
average (PTA) measured by audiometry before and after HBO therapy. The
effects of prognostic factors on hearing recovery were also evaluated.





Results:
Thirteen (27%) patients responded to HBO therapy. The remaining 35 (73%)
patients did not show any improvement. After HBO therapy, significant
improvement was found in mean hearing thresholds at all frequencies.
Only the level of initial PTA level and gender were significantly
associated with recovery. Patients with severe hearing loss (≥70 dB) had
significantly better results.




Conclusion:
Salvage HBO therapy may be beneficial in patients with ISSNHL who failed
to recover by primary combined steroid therapy. Further hearing
recovery with salvage HBO therapy can be expected, particularly in
patients with PTA greater than 70 dB.

Keywords

Hyperbaric oxygen therapy, idiopathic sensorineural hearing loss, salvage therapy

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