Evaluation of positive results for autologous serum skin testing in patients with seasonal allergic rhinitis compared with healthy controls

Year 2018, Volume: 8 Issue: 3, 151 - 154, 18.12.2018

Aslıhan Çakır Akay Esin Yalçınkaya

https://doi.org/10.32448/entupdates.499028

Abstract

Objective: Autologous serum skin testing is a practical test
for basophil histamine release which is used in the diagnosis of
chronic autoimmune urticaria. Although the exact autoimmune
pathogenesis of allergic diseases of the upper respiratory tract
remains a matter of debate, recent studies have reported positive
autologous serum skin tests in both allergic and non-allergic
rhinitis, asthma sufferers, and even in healthy controls. In this
study, we aim to evaluate positive results from autologous serum
testing in hayfever sufferers and to compare the results with those
from healthy controls.

Materials and methods

The study included 76 seasonal allergic rhinitis patients aged
between 18-65 years and 51 healthy volunteers who underwent
autologous serum skin testing. The Chi-squared test was used for
comparisons between the two groups.

Result

Autologous serum testing proved positive in 29 of the patients with
allergic rhinitis and in 10 of the healthy controls. The number of
positive results from autologous serum testing was found to be
significantly higher in patients with allergic rhinitis than in the
control group.

Conclusion

From the results of this research and the information found in the
literature, it appears that autologous serum skin testing has uses
beyond merely detecting chronic urticaria. There may be an advantage
in evaluating the common features and serum factor in patients with
allergic rhinitis and urticaria who show positivity to autologous
serum skin testing.

Keywords

Evaluation of positive results for autologous serum skin testing in patients with seasonal allergic rhinitis compared with healthy controls

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