Carotid body tumors: What have we learned in 5 years?

Year 2020, Volume: 10 Issue: 2, 306 - 310, 25.08.2020

Bengu Cobanoglu Selçuk Arslan Osman Bahadır Ümit Işık Mehmet İmamoglu

https://doi.org/10.32448/entupdates.708851

Abstract

Objectives: The present study aimed to retrospectively evaluate patients who were operated for carotid body tumors (CBT) in our clinic.

Methods: The present study involved 19 patients who underwent surgical CBT removal in the Otorhinolaryngology- Head and Neck Surgery Department of Karadeniz Technical University Medical Faculty between 2013 and 2018. Sociodemographic characteristics, clinical presentation and findings of physical examination, Shamblin classifications based on preoperative radiological images, surgical procedure, histopathological diagnosis and complications were recorded from hospital records.

Results: Seven of the patients were male and 12 were female. The mean age of the patients was 48.8 years and the most frequent symptom was a painless mass in the neck. According to the Shamblin classification, seven of our patients had Shamblin type I, nine patients had Shamblin type II and three patients had Shamblin type III tumors. Twelve patients had preoperative embolization of the tumor and seven patients were operated without embolization. Three patients had intraoperative carotid artery injury-related complications, whereas one patient had weakness in tongue movements due to hypoglossal nerve paresis.

Conclusion: The main treatment for CBT is surgery, however, preoperative embolization is still controversial. Successful management of patients with CBT can be achieved via a multidisciplinary approach with the participation of head and neck surgery, cardiovascular surgery and radiology departments.

Keywords

Surgery, carotid body tumor, paraganglioma

References

• 1. Lack EE, Wieneke J. Tumors of the autonomic nervous system, including paraganglia. In Fletcher CDM, editor. Diagnostic Histopathology of Tumors. Philadelphia, PA: Elsevier Saunders; 2013. p. 2064-85.
• 2. Sevil FC, Tort M, Kaygin MA. Carotid Body Tumor Resection: Long-Term Outcome of 67 Cases without Preoperative Embolization. Ann Vasc Surg 2020 Mar 28. doi: 10.1016/j.avsg.2020.03.030. [Epub ahead of print].
• 3. McCaffrey TV, Meyer FB, Michels VV, Piepgras DG, Marion MS. Familial paragangliomas of the head and neck. Arch Otolaryngol Head Neck Surg 1994;120:1211-6.
• 4. Cobb AN, Barkat A, Daungjaiboon W, et al. Carotid body tumor resection: just as safe without preoperative embolization. Ann Vasc Surg 2018;46:54-9.
• 5. Saldana MJ, Salem LE, Travezan R. High altitude hypoxia and chemodectomas. Hum Pathol 1973;4:251-63.
• 6. Chedid A, Jao W. Hereditary tumors of the carotid bodies and chronic obstructive pulmonary disease. Cancer 1974;33:1635-41.
• 7. Colen TY, Mihm FG, Mason TP, Roberson JB. Catecholamine-secreting paragangliomas: recent progress in diagnosis and perioperative management. Skull Base 2009;19:377-85.
• 8. Bercin S, Muderris T, Sevil E, Gul F, Kılıcarslan A, Kiris M. Efficiency of preoperative embolization of carotid body tumor. Auris Nasus Larynx 2015;42:226-30.
• 9. Shamblin WR, ReMine WH, Sheps EG, Harrison EG Jr. Carotid body tumor (chemodectoma). Clinicopathological analysis of ninety cases. Am J Surg 1971;122:732-9.
• 10. Wang SJ, Wang MB, Barauskas TM, Calcaterra TC. Surgical management of carotid body tumors. Otolaryngol Head Neck Surg. 2000;123:202-6.
• 11. Luna-Ortiz K, Rascon-Ortiz M, Villavicencio-Valencia V, Granados-Garcia M, Herrera-Gomez A. Carotid body tumors: review of a 20-year experience. Oral Oncol 2005;41:56-61.
• 12. Gad A, Sayed A, Elwan H, et al. Carotid body tumors: a review of 25 years experience in diagnosis and management of 56 tumors. Ann Vasc Dis 2014;7:292-9.
• 13. Torrealba JI, Valdés F, Krämer AH, Mertens R, Bergoeing M, Mariné L. Management of Carotid Bifurcation Tumors: 30-Year Experience. Ann Vasc Surg 2016;34:200-5.
• 14. Sevil FC. Management and outcomes of vascular reconstruction in carotid body tumor resection: retrospective analysis of 60 cases. Eur Arch Otorhinolaryngol 2020 Apr 25. doi: 10.1007/s00405-020-05975-z. [Epub ahead of print].
• 15. Power AH, Bower TC, Kasperbauer J, et al. Impact of preoperative embolization on outcomes of carotid body tumor resections. J Vasc Surg 2012;56:979-89.
• 16. Bercin S, Muderris T, Sevil E, Gul F, Kılıcarslan A, Kiris M. Efficiency of preoperative embolization of carotid body tumor. Auris Nasus Larynx 2015;42:226-30.
• 17. Robertson V, Poli F, Hobson B, Saratzis A, Ross Naylor A. A Systematic Review and Meta-Analysis of the Presentation and Surgical Management of Patients With Carotid Body Tumours. Eur J Vasc Endovasc Surg 2019;57:477-86.
• 18. Pacheco-Ojeda LA. Carotid body tumors: surgical experience in 215 cases. J Craniomaxillofac Surg 2017;45:1472-7.