Research Article

Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions

Volume: 60 Number: 1 May 20, 2026
EN

Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions

Abstract

Purpose The Canary Caries Detection System has been shown to quantify the degree of demineralization of incipient enamel. The objective of this study was to evaluate and compare demineralization changes after applying various toothpastes on incipient enamel lesions utilizing the Canary Caries Detection System.

Materials and Methods Thirty-five extracted human teeth premolars were divided into seven groups (n=5). Each group was demineralized in a lactate acid buffer solution (pH 4.5) and tested using one of six toothpastes or a phosphate buffer solution (control, pH 7.4). The teeth were brushed according to manufacturer’s instructions daily for 28 days. Canary Numbers, standardized cold light, and fluorescent photographs were collected at the initial (T0), following demineralization (T1), day 14 (T2), and day 28 (T3).

Results It was found that there was a statistical difference between all groups and the control between T2-T3 (p<0.046 facial surfaces) and T1-T3 (p<0.015 lingual surfaces). There was also a statistical difference between T1-T3 when comparing all groups. The cold light and fluorescent light photos also show evidence of changes in demineralization from T1-T3 in the PreviDent 5000 Plus group.

Conclusion The PreviDent 5000 Plus group demonstrated a statistical difference to Clinpro 5000, MI Paste Plus and PreviDent 5000 Booster Plus from T1-T3 as the Canary Numbers decreased. There was an increase and significant difference in the PBS group Canary Numbers from T1-T3, indicating the negative control showed continued demineralization. 

Keywords

References

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Details

Primary Language

English

Subjects

Dental Materials and Equipment

Journal Section

Research Article

Publication Date

May 20, 2026

Submission Date

November 1, 2024

Acceptance Date

March 1, 2025

Published in Issue

Year 2026 Volume: 60 Number: 1

APA
Steel, S., Mon, H., Xu, X., Chapple, A., Grandy, H., Ballard, R., & Armbruster, P. (2026). Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions. European Oral Research, 60(1), 98-104. https://doi.org/10.26650/eor.20251568648
AMA
1.Steel S, Mon H, Xu X, et al. Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions. EOR. 2026;60(1):98-104. doi:10.26650/eor.20251568648
Chicago
Steel, Skylar, Htwe Mon, Xiaoming Xu, et al. 2026. “Evaluation of Demineralization Changes Utilizing the Canary Caries Detection System and Various Toothpastes on Incipient Enamel Lesions”. European Oral Research 60 (1): 98-104. https://doi.org/10.26650/eor.20251568648.
EndNote
Steel S, Mon H, Xu X, Chapple A, Grandy H, Ballard R, Armbruster P (May 1, 2026) Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions. European Oral Research 60 1 98–104.
IEEE
[1]S. Steel et al., “Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions”, EOR, vol. 60, no. 1, pp. 98–104, May 2026, doi: 10.26650/eor.20251568648.
ISNAD
Steel, Skylar - Mon, Htwe - Xu, Xiaoming - Chapple, Andrew - Grandy, Hope - Ballard, Richard - Armbruster, Paul. “Evaluation of Demineralization Changes Utilizing the Canary Caries Detection System and Various Toothpastes on Incipient Enamel Lesions”. European Oral Research 60/1 (May 1, 2026): 98-104. https://doi.org/10.26650/eor.20251568648.
JAMA
1.Steel S, Mon H, Xu X, Chapple A, Grandy H, Ballard R, Armbruster P. Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions. EOR. 2026;60:98–104.
MLA
Steel, Skylar, et al. “Evaluation of Demineralization Changes Utilizing the Canary Caries Detection System and Various Toothpastes on Incipient Enamel Lesions”. European Oral Research, vol. 60, no. 1, May 2026, pp. 98-104, doi:10.26650/eor.20251568648.
Vancouver
1.Skylar Steel, Htwe Mon, Xiaoming Xu, Andrew Chapple, Hope Grandy, Richard Ballard, Paul Armbruster. Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions. EOR. 2026 May 1;60(1):98-104. doi:10.26650/eor.20251568648