Editorial

Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423

Volume: 60 Number: 1 June 15, 2026

Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423

Abstract

To the editor,

I read the article titled ‘Clinical and demographic profile of Oral Lichen Planus in Sri Lanka: A retrospective study authored by BSM Samadarani et al. (1). I found this article enlightening and up to the minute. The distinction between Oral Lichen Planus (OLP) and Oral lichenoid reaction (OLR) is extremely difficult due to their remarkably similar clinical and histopathological features, while clinical history triggers identification and histopathological examination remain crucial, immunohistochemistry (IHC) offers more precise understanding of the underlying mechanism. Oral lichen planus are generally bilateral lesions may or may not be symmetrical (2).

I reported a case of unilateral lichen planus in 2014 which was distinguished from lichenoid reaction due to the immunohistochemical positivity of CD 8+ T cell. CD 8 + T cell often shows a stronger positive expression in OLP than OLR (3). Recently Suzuki T et al. (4) found over -expression of COX -2 by epithelial cells in OLL, that could inferred oncogenic changes, because COX -2 was described to modulate cell proliferation and apoptosis against oncogenic alterations (5). Immunohistochemistry has emerged as a valuable adjunct to traditional diagnostic methods in differentiating OLP from OLR by providing a more detailed characterization of the inflammatory infiltrate and epithelial changes.

Keywords

References

  1. Siriwardenaa BS, Hettiarachchi K, Jayasinghe RD. Clinical and demographic profile of oral lichen planus in Sri Lanka:a retrospective study. Eur Oral Res. 2025;59:1–6. [CrossRef]
  2. Srivastava KC, Saini RS, Lin GSS, Heboyan A, Shrivastava D. A Decadal Bibliometric Analysis on the Therapeutic Strategies in Oral Lichen Planus. Health Sci Rep 2025;29:8:e70403. [CrossRef]
  3. Bajpai M, Agarwal D, Bhalla A, VatchalaRani RM, Kumar M. Unilateral lichen planus:A rare case report. J Nat Sci Biol Med. 2014;5:453–5. [CrossRef]
  4. Suzuki T, Suemitsu M, Nakayama M, Taguchi C, Ukigaya M, Nakamura C, et al. Histopathological and Immunohistochemical Study of the Distinction between Oral Lichen Planus and Oral Lichenoid Lesions. Open J Stomatol. 2021;11:91–6. [CrossRef]
  5. Arber N. Cyclooxygenase-2 inhibitors in colorectal cancer prevention:point. Cancer Epidemiol Biomarkers Prev. 2008;17:1852–7. [CrossRef]

Details

Primary Language

English

Subjects

Dental Therapeutics, Pharmacology and Toxicology, Oral Medicine and Pathology

Journal Section

Editorial

Publication Date

June 15, 2026

Submission Date

March 1, 2025

Acceptance Date

March 15, 2025

Published in Issue

Year 2026 Volume: 60 Number: 1

APA
Bajpai, M. (2026). Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423. European Oral Research, 60(1), 121-121. https://doi.org/10.26650/eor.20251649226
AMA
1.Bajpai M. Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423. EOR. 2026;60(1):121-121. doi:10.26650/eor.20251649226
Chicago
Bajpai, Manas. 2026. “Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and Demographic Profile of Oral Lichen Planus in Sri Lanka: a Retrospective Study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650 Eor.20241331423”. European Oral Research 60 (1): 121-21. https://doi.org/10.26650/eor.20251649226.
EndNote
Bajpai M (June 1, 2026) Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423. European Oral Research 60 1 121–121.
IEEE
[1]M. Bajpai, “Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423”, EOR, vol. 60, no. 1, pp. 121–121, June 2026, doi: 10.26650/eor.20251649226.
ISNAD
Bajpai, Manas. “Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and Demographic Profile of Oral Lichen Planus in Sri Lanka: a Retrospective Study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650 Eor.20241331423”. European Oral Research 60/1 (June 1, 2026): 121-121. https://doi.org/10.26650/eor.20251649226.
JAMA
1.Bajpai M. Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423. EOR. 2026;60:121–121.
MLA
Bajpai, Manas. “Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and Demographic Profile of Oral Lichen Planus in Sri Lanka: a Retrospective Study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650 Eor.20241331423”. European Oral Research, vol. 60, no. 1, June 2026, pp. 121-, doi:10.26650/eor.20251649226.
Vancouver
1.Manas Bajpai. Comments on Siriwardena S, Hettiarachchi K, Jayasinghe R. Clinical and demographic profile of oral lichen planus in Sri Lanka: a retrospective study. Eur Oral Res 2025; 59(1): 1-6. DOI: 10.26650/ eor.20241331423. EOR. 2026 Jun. 1;60(1):121-. doi:10.26650/eor.20251649226