Research Article
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Year 2021, Volume: 55 Issue: 3, 139 - 145, 21.09.2021
https://doi.org/10.26650/eor.2021853507

Abstract

References

  • 1. TateAR, AcsG. Dental postoperative pain management in children. Dent Clin North Am 2002; 46:707–17. [CrossRef ]
  • 2. Ozlem Velioglu, Aylin Sipahi, Huseyin Koca, Emre Velioglu. Bupivacaine vs. lidocaine: a comparison of local anesthetic efficacy in impacted third molar surgery. Clin Oral Investig 2020; 24:3539-46. [CrossRef ]
  • 3. Matthews DC, McCulloch CAG. Evaluating patient perceptions as short-term outcomes of periodontal treatment: a comparison of surgical and non-surgical therapy. J Periodontol 1993;64:990– 7. [CrossRef ]
  • 4. Gordon SM, Mischenko AV, Dionne RA. Long-Acting Local Anesthetics and Peri operative Pain Management. Dent Clin North Am 2010;54:611–20. [CrossRef ]
  • 5. Coventry J, Griffiths G, Scully C, Tonetti M. Periodontal disease. BMJ 2000; 321:36–9. [CrossRef ]
  • 6. Julian Diaz-Abele MD, Mario Luc MD, Alina Dyachenko, Salah Aldekhayel, Antonio Ciampi, Jane Mc Cusker. Lidocaine with epinephrine versus bupivacaine with epinephrine as local anesthetic agents in wide-awake hand surgery: a pilot outcome study of patient’s pain perception. J Hand Surg Glob Online 2020;2:1-6. [CrossRef ]
  • 7. Katz J. George Washington Crile, anoci-association, and pre- emptive analgesia. Pain 1993;53:243–5. [CrossRef ]
  • 8. Kehlet H, Dahl JB. The value of “multimodal” or “balanced analgesia” in postoperative pain treatment. Anesth Analg 1993;77:1048–56. [CrossRef ]
  • 9. Woolf CJ, Chong MS. Preemptive analgesia--treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 1993;77:362–79. [CrossRef ]
  • 10. Braganza A, Bissada N, Hatch C, Ficara A. The effect of non- steroidal anti-ınflammatory drugs on bleeding during periodontal surgery. J Periodontol 2005;76:1154–60. [CrossRef ]
  • 11. Dal Pra DJ, Strahan JD. A clinical evaluation of the benefits of a course of oral penicillin following periodontal surgery. Aust Dent J 1972;17:219–21. [CrossRef ]
  • 12. Pradhan S, Shrestha R, Gorkhali RS. Pain perception after periodontal therapies. J Nepal Soc Perio Oral Implantol 2018;2:56-60. [CrossRef ]
  • 13. Scott J, Huskisson EC. Vertical or horizontal visual analogue scales. Ann Rheum Dis 1979;38:560. [CrossRef ]
  • 14. Chandrashekhar Pandey, Alexander Speedie, Rahul Jaiswal, Shishir Lanjewar, Yadnesh Dondulkar. Role of bupivacaine in dentistry. Int J Oral Health Med Res 2019; 6:53-55.
  • 15. MoorePA, DunskyJL. Bupivacaine anesthesia—a clinical trial for endodontic therapy. Oral Surg Oral Med Oral Pathol 1983;55:176–9. [CrossRef ]
  • 16. McLureHA, RubinAP. Review of local anaesthetic agents. Minerva Anestesiol 2005;71:59–74.
  • 17. Malamed SF. Handbook of Local Anesthesia. Elsevier Health Sciences; 2014.
  • 18. Trieger N, Gillen GH. Bupivacaine anesthesia and post-operative analgesia in oral surgery. Anesth Prog 1979; 26:20–3.
  • 19. Chapman PJ, Macleod AWG. A clinical study of bupivacaine for mandibular anesthesia in oral surgery. Anesth Prog 1985;32:69–72.
  • 20. Bouloux GF, Punnia-Moorthy A. Bupivacaine versus lidocaine for third molar surgery: a double-blind, randomized, crossover study. J Oral Maxillofac Surg 1999;57:510–4. [CrossRef ]
  • 21. Sampaio RM, Carnaval TG, Lanfredi CB, Horliana ACRT, Rocha RG, Tortamano IP. Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar. J Endod 2012;38:594–7. [CrossRef ]
  • 22. Bellini HT. The time factor in periodontal therapy. A pilot study correlating treatment time and plaque, calculus, pocket depth, and number of teeth. J Periodontal Res 1974; 9:56–61.
  • 23. Aps C, Reynolds F. The effect of concentration on vasoactivity of bupivacaine and lignocaine. Br J Anaesth 1976;48:1171–4. [CrossRef ]
  • 24. Baab DA, Ammons Jr WF, Selipsky H. Blood loss during periodontal flap surgery. J Periodontol 1977;48:693–8. [CrossRef ]
  • 25. Zigdon H, Levin L, Filatov M, Oettinger-Barak O, Machtei EE. Intraoperative bleeding during open flap debridement and regenerative periodontal surgery. J Periodontol 2012; 83:55–60. [CrossRef ]
  • 26. Gordon SM, Brahim JS, Dubner R, McCullagh LM, Sang C, Dionne RA. Attenuation of pain in a randomized trial by suppression of peripheral nociceptive activity in the immediate postoperative period. Anesth Analg 2002; 95:1351–7. [CrossRef ]
  • 27. Moore PA. Bupivacaine: a long-lasting local anesthetic for dentistry. Oral Surg Oral Med Oral Pathol 1984;58:369–74. [CrossRef ]
  • 28. Gordon SM, Chuang BP, Wang XM, Hamza MA, Rowan JS, Brahim JS, et al. The differential effects of bupivacaine and lidocaine on prostaglandin e2 release, cyclooxygenase gene expression and pain in a clinical pain model. Anesth Analg 2008;106:321–7. [CrossRef ]
  • 29. Adsan H, Tulunay M, Onaran O. The effects of verapamil and nimodipine on bupivacaine- induced cardiotoxicity in rats: an in vivo and in vitro study. Anesth Analg 1998;86:818–24. [CrossRef ]
  • 30. Roitman K, Sprung J, Wallace M, Matjasko J. Enhancement of bupivacaine cardiotoxicity with cardiac glycosides and beta- adrenergic blockers: a case report. Anesth Analg 1993;76:658– 61. [CrossRef ]
  • 31. Su N, Wang H, Zhang S, Liao S, Yang S, Huang Y. Efficacy and safety of bupivacaine versus lidocaine in dental treatments: a meta-analysis of randomised controlled trials. Int Dent J 2014;64:34–45. [CrossRef ]

Comparison of efficacy and pain perception using 0.5% Bupivacaine and 2% Lidocaine in periodontal Surgery – A split mouth randomized clinical trial

Year 2021, Volume: 55 Issue: 3, 139 - 145, 21.09.2021
https://doi.org/10.26650/eor.2021853507

Abstract

Purpose To evaluate the effectiveness of bupivacaine and lidocaine local anesthesia on the intra-surgical and post-surgical pain control in patients undergoing periodontal flap surgery. Materials and Methods A randomized, single-blind, split-mouth design was employed in patients who are scheduled for periodontal flap surgery for at least two similar sextants with similar anesthetic techniques. Fifty patients (age range 16-65 years, 32 males and 28 females) enrolled in the present study. On one-site, the flap surgery was performed using 2% lidocaine with 1:200000 epinephrine and on the other with 0.5% bupivacaine with 1:200000 epinephrine. Base line clinical parameters, probing pocket depth, clinical attachment level were recorded. Pain during intra operative period, at the time of loss of numbness and for three consecutive days was measured using visual analog scale (VAS). Results Significant differences were observed between the two groups in the intra operative pain scores (p=0.0045) and pain scores at the time of loss of numbness (p=0.0005) but not at the 1st, 2nd and 3rd day after the surgery. Conclusion Bupivacaine was markedy more effective than the lidocaine. Thus the usage of bupivacaine can be substantiated for periodontal surgeries for the control of pain in the intra operative and immediate post-operative period to increase patients’ comfort.

References

  • 1. TateAR, AcsG. Dental postoperative pain management in children. Dent Clin North Am 2002; 46:707–17. [CrossRef ]
  • 2. Ozlem Velioglu, Aylin Sipahi, Huseyin Koca, Emre Velioglu. Bupivacaine vs. lidocaine: a comparison of local anesthetic efficacy in impacted third molar surgery. Clin Oral Investig 2020; 24:3539-46. [CrossRef ]
  • 3. Matthews DC, McCulloch CAG. Evaluating patient perceptions as short-term outcomes of periodontal treatment: a comparison of surgical and non-surgical therapy. J Periodontol 1993;64:990– 7. [CrossRef ]
  • 4. Gordon SM, Mischenko AV, Dionne RA. Long-Acting Local Anesthetics and Peri operative Pain Management. Dent Clin North Am 2010;54:611–20. [CrossRef ]
  • 5. Coventry J, Griffiths G, Scully C, Tonetti M. Periodontal disease. BMJ 2000; 321:36–9. [CrossRef ]
  • 6. Julian Diaz-Abele MD, Mario Luc MD, Alina Dyachenko, Salah Aldekhayel, Antonio Ciampi, Jane Mc Cusker. Lidocaine with epinephrine versus bupivacaine with epinephrine as local anesthetic agents in wide-awake hand surgery: a pilot outcome study of patient’s pain perception. J Hand Surg Glob Online 2020;2:1-6. [CrossRef ]
  • 7. Katz J. George Washington Crile, anoci-association, and pre- emptive analgesia. Pain 1993;53:243–5. [CrossRef ]
  • 8. Kehlet H, Dahl JB. The value of “multimodal” or “balanced analgesia” in postoperative pain treatment. Anesth Analg 1993;77:1048–56. [CrossRef ]
  • 9. Woolf CJ, Chong MS. Preemptive analgesia--treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 1993;77:362–79. [CrossRef ]
  • 10. Braganza A, Bissada N, Hatch C, Ficara A. The effect of non- steroidal anti-ınflammatory drugs on bleeding during periodontal surgery. J Periodontol 2005;76:1154–60. [CrossRef ]
  • 11. Dal Pra DJ, Strahan JD. A clinical evaluation of the benefits of a course of oral penicillin following periodontal surgery. Aust Dent J 1972;17:219–21. [CrossRef ]
  • 12. Pradhan S, Shrestha R, Gorkhali RS. Pain perception after periodontal therapies. J Nepal Soc Perio Oral Implantol 2018;2:56-60. [CrossRef ]
  • 13. Scott J, Huskisson EC. Vertical or horizontal visual analogue scales. Ann Rheum Dis 1979;38:560. [CrossRef ]
  • 14. Chandrashekhar Pandey, Alexander Speedie, Rahul Jaiswal, Shishir Lanjewar, Yadnesh Dondulkar. Role of bupivacaine in dentistry. Int J Oral Health Med Res 2019; 6:53-55.
  • 15. MoorePA, DunskyJL. Bupivacaine anesthesia—a clinical trial for endodontic therapy. Oral Surg Oral Med Oral Pathol 1983;55:176–9. [CrossRef ]
  • 16. McLureHA, RubinAP. Review of local anaesthetic agents. Minerva Anestesiol 2005;71:59–74.
  • 17. Malamed SF. Handbook of Local Anesthesia. Elsevier Health Sciences; 2014.
  • 18. Trieger N, Gillen GH. Bupivacaine anesthesia and post-operative analgesia in oral surgery. Anesth Prog 1979; 26:20–3.
  • 19. Chapman PJ, Macleod AWG. A clinical study of bupivacaine for mandibular anesthesia in oral surgery. Anesth Prog 1985;32:69–72.
  • 20. Bouloux GF, Punnia-Moorthy A. Bupivacaine versus lidocaine for third molar surgery: a double-blind, randomized, crossover study. J Oral Maxillofac Surg 1999;57:510–4. [CrossRef ]
  • 21. Sampaio RM, Carnaval TG, Lanfredi CB, Horliana ACRT, Rocha RG, Tortamano IP. Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar. J Endod 2012;38:594–7. [CrossRef ]
  • 22. Bellini HT. The time factor in periodontal therapy. A pilot study correlating treatment time and plaque, calculus, pocket depth, and number of teeth. J Periodontal Res 1974; 9:56–61.
  • 23. Aps C, Reynolds F. The effect of concentration on vasoactivity of bupivacaine and lignocaine. Br J Anaesth 1976;48:1171–4. [CrossRef ]
  • 24. Baab DA, Ammons Jr WF, Selipsky H. Blood loss during periodontal flap surgery. J Periodontol 1977;48:693–8. [CrossRef ]
  • 25. Zigdon H, Levin L, Filatov M, Oettinger-Barak O, Machtei EE. Intraoperative bleeding during open flap debridement and regenerative periodontal surgery. J Periodontol 2012; 83:55–60. [CrossRef ]
  • 26. Gordon SM, Brahim JS, Dubner R, McCullagh LM, Sang C, Dionne RA. Attenuation of pain in a randomized trial by suppression of peripheral nociceptive activity in the immediate postoperative period. Anesth Analg 2002; 95:1351–7. [CrossRef ]
  • 27. Moore PA. Bupivacaine: a long-lasting local anesthetic for dentistry. Oral Surg Oral Med Oral Pathol 1984;58:369–74. [CrossRef ]
  • 28. Gordon SM, Chuang BP, Wang XM, Hamza MA, Rowan JS, Brahim JS, et al. The differential effects of bupivacaine and lidocaine on prostaglandin e2 release, cyclooxygenase gene expression and pain in a clinical pain model. Anesth Analg 2008;106:321–7. [CrossRef ]
  • 29. Adsan H, Tulunay M, Onaran O. The effects of verapamil and nimodipine on bupivacaine- induced cardiotoxicity in rats: an in vivo and in vitro study. Anesth Analg 1998;86:818–24. [CrossRef ]
  • 30. Roitman K, Sprung J, Wallace M, Matjasko J. Enhancement of bupivacaine cardiotoxicity with cardiac glycosides and beta- adrenergic blockers: a case report. Anesth Analg 1993;76:658– 61. [CrossRef ]
  • 31. Su N, Wang H, Zhang S, Liao S, Yang S, Huang Y. Efficacy and safety of bupivacaine versus lidocaine in dental treatments: a meta-analysis of randomised controlled trials. Int Dent J 2014;64:34–45. [CrossRef ]
There are 31 citations in total.

Details

Primary Language English
Subjects Dentistry
Journal Section Original Research Articles
Authors

Tss Manikanta This is me 0000-0002-2194-0435

Cd Dwarakanath This is me 0000-0002-0506-5191

Ksv Ramesh 0000-0001-7022-0023

Ps Gautami This is me 0000-0002-8744-1452

Nvsg Sruthıma This is me 0000-0002-7126-5829

Publication Date September 21, 2021
Submission Date January 4, 2021
Published in Issue Year 2021 Volume: 55 Issue: 3

Cite

EndNote Manikanta T, Dwarakanath C, Ramesh K, Gautami P, Sruthıma N (September 1, 2021) Comparison of efficacy and pain perception using 0.5% Bupivacaine and 2% Lidocaine in periodontal Surgery – A split mouth randomized clinical trial. European Oral Research 55 3 139–145.