In Vitro Evaluation of Anticancer Activity of Moringa Peregrina Seeds on Breast Cancer Cells

Abstract

Moringa peregrina have long been used traditionally to treat many diseases in Arabian Peninsula folklore medicine. The objective of this study was to determine the anticancer activity of Moringa peregrina seed ethanolic extract (MPSE) on the breast cancer cell. The 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium bromide (MTT) assay was used to determine the anticancer effect of MPSE treatment at concentrations ranging from 25 to 400 μg/ml against AU565 breast cancer cells. The statistical values were determined employing the statistical test of one-way analysis of variance. The results show that the MPSE inhibits the proliferation of AU565 breast cancer cells with IC50 values 201.7μg/ml. These findings suggest that MPSE has anti-proliferative effect on AU565 breast cancer cells can be used to treat and prevent cancer diseases, the outcomes is promising and paving the way for develop new natural drug for treatment of breast cancer disease.

Keywords

• Moringa peregrina
• Cytotoxicity Activity
• AU565 cell

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