Review
BibTex RIS Cite

ZİRKONYUM DESTEKLİ SABİT PROTETİK RESTORASYONLARDA KLİNİK BAŞARI DEĞERLENDİRME KRİTERLERİ

Year 2019, , 53 - 62, 28.06.2019
https://doi.org/10.35333/ERD.2019.14

Abstract

Sabit protetik restorasyonlarda metal destekli seramik restorasyonlar klinik olarak uzun yıllardan beri başarıyla kullanılmalarına rağmen yapısındaki metal alt yapının; restorasyonun ışık geçirgenliğini azaltarak estetik sakıncalara yol açması, özellikle marjinlerde metal-iyon renklenmesi ile gri renkte hoş olmayan bir görüntüye sahip olması, lokal doku reaksiyonuna ve korozyon toksisitesine sebep olabilmesi gibi dezavantajlarından ötürü bu materyal yerine yeni arayışların doğmasını gerektirmiştir. Günümüzde çok sayıda güçlendirilmiş tam seramik sistemi geliştirilmiştir. Güçlendirilmiş tam seramik sistemleri arasında zirkonyum esaslı seramik restorasyonlar, yüksek dayanıklılık ve estetik özelliklerinden dolayı tercih edilirler. Klinikte zirkonyum oksitin kor materyali olarak kullanımı tatminkar optik özellikler, 1000 MPa’ı geçen yüksek bükülme direnci, biyolojik uyumluluğu ve translüsent olması gibi avantajları sayesınde tercih edilmektedir. Bunlardan en yaygın olarak kullanılanı yttrium ile stabilize edilmiş zirkonyum oksit polikristalleridir. Kullanılan materyallerin ve uygulama tekniklerinin başarılarını ve özelliklerini belirleyebilmek, restorasyonların klinik prognozunu belirlemek, restorasyonları oral çevrede değerlendirebilmek amacıyla kontrollü klinik çalışmalara ihtiyaç vardır. Bu nedenle bir takım klinik başarı değerlendirme kriterleri oluşturularak standardizasyona bağlanmıştır. Belli standartlar ölçütünde restorasyonun klinik olarak değerlendirilmesi ve başarısına karar verilmesi mümkündür.

References

  • Akkayan B, Gülmez T. Resistance to fracture of endodontically treated teeth restored with different post systems. J Prosthet Dent. 2002; 87;431-7.
  • Al-Amleh B, Lyons K, Swain M. Clinical trials in zirconia: a systematic review. J Oral Rehabil. 2010; 37(8):641-52.
  • Anusavice KJ. Quality Evalution of Dental Restorations. Criteria of Placement and Replacement, Chicago: Quintessence Publishing Co,: 1989; 352-400.
  • Batson ER, Cooper LF, Duqum I, Mendonca G. Clinical outcomes of three different crown systems with CAD/CAM technology. J Prosthet Dent. 2014; 112: 770-777.
  • Beier US, Kapferer I, Burtscher D, Dumfahrt H. Clinical performance of porcelain laminate veneers for up to 20 years. Int J Prosthodont. 2012; 25:79-85.
  • Beuer F, Schweiger J, Edelhoff D. Digital dentistry: an overview of recent developments for CAD/CAM generated restorations. J Br Dent. 2008; 204: 505-511.
  • Bindl A, Mörmann WH. Marginal and internal fit of all-ceramic CAD/CAM crown-coping on chamfer preparations. J Oral. Rehabil. 2005; 32: 441- 447.
  • Burgess J, Janyavula S, Lawson NC, Lucas TJ, Cakir D. Enamel wear opposing polished and aged zirconia. Oper Dent. 2014; 39(2):189-194.
  • Carranza FA, Newman MG. Clinical Periodontology, 8th Edition. WB Saunders Company,; 1996;564-658.
  • Coelho-De-Souza FH, Camargo JC, Beskow T, Balestrin MD, Klein-Junior CA, Demarco FF.A randomized double-blind clinical trial of posterior composite restorations with or without bevel: 1-year follow-up. J Appl Oral Sci. 2012; 20(2):174-179.
  • Craig RG, Powers JM. Restorative Dental Materals, 11th Edition. Toronto: Mosby Co,: 2002; 53-65.
  • Curtis AR, Wright AJ, Fleming GJP. The influence of surface modification techniques on the performance of a Y-TZP dental ceramic. J Dent. 2006; 34(3):195-206.
  • Denry I, Kelly JR. State of the art of zirconia for dental applications. Dent Mater. 2008; 24: 299-307.
  • Frese C, Schiller P, Staehle HJ, Wolff D. Recontouring teeth and closing diastemas with direct composite buildups: a 5-year follow-up. J Dent. 2013; 41(11):979-985.
  • Gargari M, Gloria F, Napoli E, Pujia A.M, Zirconia: cementation of prosthetic restorations. Literature review, Oral implantol. 2010; 3(4): 25–29.
  • Hickel R, Peschke A, Tyas M, Mjör I. FDI World Dental Federation: clinical criteria for the evaluation of direct and indirect restorations-update and clinical examples. Clin Oral Invest. 2010; 14:349–366.
  • Ishibe M, Raigrodski AJ, Flinn BD, Chung KH, Spiekerman C, Winter RR. Shear bond strengths of pressed and layered veneering ceramics to high-noble alloy and zirconia cores. J Prosthet Dent. 2011; 105:29-37.
  • Ji MK, Park JH, Park SW, Yun K, Oh GJ, Lim HP. Evaluation of marginal fit of 2 CAD-CAM anatomic contour zirconia crown systems and lithium disilicate glass-ceramic crown. J Adv Prosthodont. 2015;7:271-277.
  • Jung YS, Lee JW, Choi YJ, Ahn JS, Shin SW,Huh JB. A study on the in-vitro wear of the natural tooth structure by opposing zirconia or dental porcelain. J Adv Prosthodont. 2010;2:111-115.
  • Kara D. Monolitik ve çift katmanlı zirkonya seramik kuronların kenar uyumlarının ve kırılma dirençlerinin in vitro olarak değerlendirilmesi. AMÜ Sağlık Bilimleri Enstitüsü, Uzmanlık Tezi, 2016, Aydın (Danışman: Yard. Doç. Dr. Baykal Yılmaz)
  • Kelly JR. Dental ceramics: current thinking and trends. Dent Clin North Am. 2004; 48(2):513- 530.
  • Knoernschild KL, Campbell SD. Periodontal tissue responses after insertion of artificial crowns and fixed partial dentures. J Prosthet Dent. 2000; 84: 492-507.
  • Kurıyama S, Teruı Y, Hıguchı D, Goto D, Hotta Y, Manabe A, Takashi Miyazaki. Novel fabrication method for zirconia restorations: Bonding strength of machinable ceramic to zirconia with resin cements, J Dent Mater. 2011; 30(3):419-424.
  • Lughi V, Sergo V. Low temperature degradation-aging of zirconia: A critical review of the relevant aspects in dentistry. Dent Mater. 2010; 26(8):807-20
  • Marchack BW, Sato S, Marchack CB, White SN. Complete and partial contour zirconia designs for crowns and fixed dental prostheses: a clinical report. J Prosthet Dent. 2011; 106: 145-152.
  • Marquillier T, Doméjean S, Le Clerc J, Chemla F, Gritsch K, Maurin JC, Millet P, Perard M, Grosgogeat B, Dursun E. The use of FDI criteria in clinical trials on direct dental restorations: A scoping review. J Dent. 2017; 68:1-9.
  • Monaco C, Ferrari M, Caldari M, Baldissara P, Scotti R. Comparison of 2 bonding systems and survival of fiber-reinforced composite inlay fixed partial dentures. Int J Prosthodont. 2006; 19:577-85.
  • O’Brien WJ. Dental Materials and Their Selection, 3 rd ed. Canada, Quintessence, 2002; 132,35-143,46.
  • Piconi C, Macauro G. Zirconia as a ceramic biomaterial. Biomaterials. 1999; 20: 1-25.
  • Poggio CE, Dosoli R, Ercoli C. A retrospective analysis of 102 zirconia single crowns with knife-edge margins. J Prosthet Dent. 2012; 107:316-21.
  • Raigrodski AJ, Chiche GJ, Potiket N, Hochstedler JL, Mohamed SE, Billiot S, Mercante DE. The efficacy of posterior three-unit zirconium-oxide-based ceramic fixed partial dental prostheses: A prospective clinical pilot study. J Prosthet Dent. 2006; 96:237-244.
  • Raigrodski AJ, Chiche GJ. The safety and efficacy of anterior ceramic fixed partial dentures: A review of the literature. J Prosthet Dent. 2001; 86: 520-525.
  • Raigrodski AJ, Hillstead MB, Meng GK, Chung KH. Survival and complications of zirconia-based fixed dental prostheses: a systematic review. J Prosthet Dent. 2012; 107:170-177.
  • Raigrodski AJ. Contemporary materials and technologies for all-ceramic fixed partial dentures: a review of the literature. J Prosthet Dent. 2004; 92(6):557-562.
  • Randall RC, Wilson NHF. Clinical testing of restorative materials some historical landmarks. J Dent. 1999;27:543-50.
  • Rimondini L, Cerroni L, Carrassi A, Torricelli P. Bacterial colonization of zirconia ceramic surfaces: an in vitro and in vivo study. Int J Oral Maxillofac Implants. 2002; 17: 793-798.
  • Sailer I, Bonani T, Brodbeck U, Hämmerle CH. Retrospective clinical study of single-retainer cantilever anterior and posterior glass-ceramic resin-bonded fixed dental prostheses at a mean follow-up of 6 years. Int J Prosthodont. 2013; 26:443-50.
  • Sailer I, Feher A, Filser F, Gauckler LJ, Lüthy H, Hämmerle CH. Five-year clinical results of zirconia frameworks for posterior fixed partial dentures. Int J Prosthodont. 2007; 20(4): 383–8.
  • Sailer I, Feher A, Filser F, Gauckler LJ, Lüthy H, Hämmerle CH. Five-year clinical results of zirconia frameworks for posterior fixed partial dentures. Int J Prosthodont. 2007; 20(4): 383–8.
  • Sailer I, Feher A, Filser F,Gauckler LJ, Lüthy H, Hammerle CH. Prospective clinical study of zirconia posterior fixed partial dentures: 3 year follow-up. 2006. Quintessence Int 37,685-693.
  • Silva N, Sailer I, Zhang Y, Coelho PG, Guess PC, Zembic A, Kohal RJ. Performance of zirconia for dental healthcare. Materials. 2010; 3:863-896.
  • Soliman, MSM, Mohsen CA, El-Mahallawi O, Abu-Eittah MRH. Effect of Different Cement Spaces on the Vertical Marginal Gap of Full Anatomical Zirconia Bridges. J Am Sci. 2015; 11(6):145-152.
  • Staehle HJ, Wohlrab T, Saure D, Wolff D, Frese C. A 6.5-year clinical follow-up of direct resin composite buildups in the posterior dentition: introduction of a new minimally invasive restorative method. J Dent. 2015; 43(10):1211-1217.
  • Stawarczyk B, Özcan M, Roos M, Trottmann A, Sailer I, Hämmerle CHF. Load-bearing capacity and failure types of anterior zirconia crowns veneered with overpressing and layering techniques. Dent Mater. 2011; 27:1045-1053.
  • Tan F. Bilgisayar ile tasarlanarak üretilen translüsent monolitik zirkonya ve çift tabakalı zirkonya restorasyonların klinik başarılarının değerlendirilmesi. Ege Ü Sağlık Bilimleri Enstitüsü, Uzmanlık Tezi, 2016, İzmir (Danışman: Doç. Dr. Muherrem Erhan Çömlekoğlu)
  • Triwatana P, Nagaviroj N, Tulapornchai C. Clinical performance and failures of zirconia-based fixed partial dentures: a review literature. J Adv Prosthodont. 2012: 4: 76-83.
  • Tsalouchou E, Cattell MJ, Knowles JC, Pittayachawan P, McDonald A. Fatigue and fracture properties of yttria partially stabilized zirconia crown systems. Dent Mater. 2008; 24:308-318.
  • Vagkopoulou T, Koutayas SO, Koidis P, Strub JR. Zirconia in dentistry: Part 1. Discovering the nature of an upcoming bioceramic. Eur J Esthet Dent. 2009; 4 :130-151.
  • Yihong L, Hailan F, Yiwang B, Yan Q, Ning X, Zhijian S. Fracture and interfacial delamination origins of bilayer ceramic composites for dental restorations. Journal of the European Ceramic Society. 2010; 30: 1297-1305.
  • Zhang Y, Lee JJ, Srikanth R, Lawn BR. Edge chipping and flexural resistance of monolithic ceramics. Dent Mater. 2013; 29: 1201-1208.

Clinical Success Evaluation Criteria in Zirconia-Based FixedI Prosthesis

Year 2019, , 53 - 62, 28.06.2019
https://doi.org/10.35333/ERD.2019.14

Abstract

Although metal-supported ceramic restorations have been clinically used for many years with success in fixed prosthetic restorations, there is a need for an alternative because metal
infrastructures decrease light transmittance, resulting in aesthetic drawbacks. They have a grey colour due to metal–ion colouring, especially in the margins, and they might cause local tissue reaction and corrosion toxicity. Currently, several strengthened all-ceramic systems have been developed. Zirconia-based ceramic restorations are among the preferred strengthened all-ceramic systems due to their high durability and aesthetic characteristics. The use of zirconium oxide as a core material is also clinically preferred due to its advantages such as satisfactory optical properties, bending resistance of over 1000 MPa, biological compatibility and translucency. The most commonly used ones are yttria-stabilised zirconia polycrystals. In order to assess the success and characteristics of used materials and application methods, controlled clinical studies are needed to determine the clinical prognosis of restorations and evaluate restorations in the oral environment. Thus, several clinical success evaluation criteria were created and standardised. It is possible to clinically evaluate restorations and determine their success according to certain standards.

References

  • Akkayan B, Gülmez T. Resistance to fracture of endodontically treated teeth restored with different post systems. J Prosthet Dent. 2002; 87;431-7.
  • Al-Amleh B, Lyons K, Swain M. Clinical trials in zirconia: a systematic review. J Oral Rehabil. 2010; 37(8):641-52.
  • Anusavice KJ. Quality Evalution of Dental Restorations. Criteria of Placement and Replacement, Chicago: Quintessence Publishing Co,: 1989; 352-400.
  • Batson ER, Cooper LF, Duqum I, Mendonca G. Clinical outcomes of three different crown systems with CAD/CAM technology. J Prosthet Dent. 2014; 112: 770-777.
  • Beier US, Kapferer I, Burtscher D, Dumfahrt H. Clinical performance of porcelain laminate veneers for up to 20 years. Int J Prosthodont. 2012; 25:79-85.
  • Beuer F, Schweiger J, Edelhoff D. Digital dentistry: an overview of recent developments for CAD/CAM generated restorations. J Br Dent. 2008; 204: 505-511.
  • Bindl A, Mörmann WH. Marginal and internal fit of all-ceramic CAD/CAM crown-coping on chamfer preparations. J Oral. Rehabil. 2005; 32: 441- 447.
  • Burgess J, Janyavula S, Lawson NC, Lucas TJ, Cakir D. Enamel wear opposing polished and aged zirconia. Oper Dent. 2014; 39(2):189-194.
  • Carranza FA, Newman MG. Clinical Periodontology, 8th Edition. WB Saunders Company,; 1996;564-658.
  • Coelho-De-Souza FH, Camargo JC, Beskow T, Balestrin MD, Klein-Junior CA, Demarco FF.A randomized double-blind clinical trial of posterior composite restorations with or without bevel: 1-year follow-up. J Appl Oral Sci. 2012; 20(2):174-179.
  • Craig RG, Powers JM. Restorative Dental Materals, 11th Edition. Toronto: Mosby Co,: 2002; 53-65.
  • Curtis AR, Wright AJ, Fleming GJP. The influence of surface modification techniques on the performance of a Y-TZP dental ceramic. J Dent. 2006; 34(3):195-206.
  • Denry I, Kelly JR. State of the art of zirconia for dental applications. Dent Mater. 2008; 24: 299-307.
  • Frese C, Schiller P, Staehle HJ, Wolff D. Recontouring teeth and closing diastemas with direct composite buildups: a 5-year follow-up. J Dent. 2013; 41(11):979-985.
  • Gargari M, Gloria F, Napoli E, Pujia A.M, Zirconia: cementation of prosthetic restorations. Literature review, Oral implantol. 2010; 3(4): 25–29.
  • Hickel R, Peschke A, Tyas M, Mjör I. FDI World Dental Federation: clinical criteria for the evaluation of direct and indirect restorations-update and clinical examples. Clin Oral Invest. 2010; 14:349–366.
  • Ishibe M, Raigrodski AJ, Flinn BD, Chung KH, Spiekerman C, Winter RR. Shear bond strengths of pressed and layered veneering ceramics to high-noble alloy and zirconia cores. J Prosthet Dent. 2011; 105:29-37.
  • Ji MK, Park JH, Park SW, Yun K, Oh GJ, Lim HP. Evaluation of marginal fit of 2 CAD-CAM anatomic contour zirconia crown systems and lithium disilicate glass-ceramic crown. J Adv Prosthodont. 2015;7:271-277.
  • Jung YS, Lee JW, Choi YJ, Ahn JS, Shin SW,Huh JB. A study on the in-vitro wear of the natural tooth structure by opposing zirconia or dental porcelain. J Adv Prosthodont. 2010;2:111-115.
  • Kara D. Monolitik ve çift katmanlı zirkonya seramik kuronların kenar uyumlarının ve kırılma dirençlerinin in vitro olarak değerlendirilmesi. AMÜ Sağlık Bilimleri Enstitüsü, Uzmanlık Tezi, 2016, Aydın (Danışman: Yard. Doç. Dr. Baykal Yılmaz)
  • Kelly JR. Dental ceramics: current thinking and trends. Dent Clin North Am. 2004; 48(2):513- 530.
  • Knoernschild KL, Campbell SD. Periodontal tissue responses after insertion of artificial crowns and fixed partial dentures. J Prosthet Dent. 2000; 84: 492-507.
  • Kurıyama S, Teruı Y, Hıguchı D, Goto D, Hotta Y, Manabe A, Takashi Miyazaki. Novel fabrication method for zirconia restorations: Bonding strength of machinable ceramic to zirconia with resin cements, J Dent Mater. 2011; 30(3):419-424.
  • Lughi V, Sergo V. Low temperature degradation-aging of zirconia: A critical review of the relevant aspects in dentistry. Dent Mater. 2010; 26(8):807-20
  • Marchack BW, Sato S, Marchack CB, White SN. Complete and partial contour zirconia designs for crowns and fixed dental prostheses: a clinical report. J Prosthet Dent. 2011; 106: 145-152.
  • Marquillier T, Doméjean S, Le Clerc J, Chemla F, Gritsch K, Maurin JC, Millet P, Perard M, Grosgogeat B, Dursun E. The use of FDI criteria in clinical trials on direct dental restorations: A scoping review. J Dent. 2017; 68:1-9.
  • Monaco C, Ferrari M, Caldari M, Baldissara P, Scotti R. Comparison of 2 bonding systems and survival of fiber-reinforced composite inlay fixed partial dentures. Int J Prosthodont. 2006; 19:577-85.
  • O’Brien WJ. Dental Materials and Their Selection, 3 rd ed. Canada, Quintessence, 2002; 132,35-143,46.
  • Piconi C, Macauro G. Zirconia as a ceramic biomaterial. Biomaterials. 1999; 20: 1-25.
  • Poggio CE, Dosoli R, Ercoli C. A retrospective analysis of 102 zirconia single crowns with knife-edge margins. J Prosthet Dent. 2012; 107:316-21.
  • Raigrodski AJ, Chiche GJ, Potiket N, Hochstedler JL, Mohamed SE, Billiot S, Mercante DE. The efficacy of posterior three-unit zirconium-oxide-based ceramic fixed partial dental prostheses: A prospective clinical pilot study. J Prosthet Dent. 2006; 96:237-244.
  • Raigrodski AJ, Chiche GJ. The safety and efficacy of anterior ceramic fixed partial dentures: A review of the literature. J Prosthet Dent. 2001; 86: 520-525.
  • Raigrodski AJ, Hillstead MB, Meng GK, Chung KH. Survival and complications of zirconia-based fixed dental prostheses: a systematic review. J Prosthet Dent. 2012; 107:170-177.
  • Raigrodski AJ. Contemporary materials and technologies for all-ceramic fixed partial dentures: a review of the literature. J Prosthet Dent. 2004; 92(6):557-562.
  • Randall RC, Wilson NHF. Clinical testing of restorative materials some historical landmarks. J Dent. 1999;27:543-50.
  • Rimondini L, Cerroni L, Carrassi A, Torricelli P. Bacterial colonization of zirconia ceramic surfaces: an in vitro and in vivo study. Int J Oral Maxillofac Implants. 2002; 17: 793-798.
  • Sailer I, Bonani T, Brodbeck U, Hämmerle CH. Retrospective clinical study of single-retainer cantilever anterior and posterior glass-ceramic resin-bonded fixed dental prostheses at a mean follow-up of 6 years. Int J Prosthodont. 2013; 26:443-50.
  • Sailer I, Feher A, Filser F, Gauckler LJ, Lüthy H, Hämmerle CH. Five-year clinical results of zirconia frameworks for posterior fixed partial dentures. Int J Prosthodont. 2007; 20(4): 383–8.
  • Sailer I, Feher A, Filser F, Gauckler LJ, Lüthy H, Hämmerle CH. Five-year clinical results of zirconia frameworks for posterior fixed partial dentures. Int J Prosthodont. 2007; 20(4): 383–8.
  • Sailer I, Feher A, Filser F,Gauckler LJ, Lüthy H, Hammerle CH. Prospective clinical study of zirconia posterior fixed partial dentures: 3 year follow-up. 2006. Quintessence Int 37,685-693.
  • Silva N, Sailer I, Zhang Y, Coelho PG, Guess PC, Zembic A, Kohal RJ. Performance of zirconia for dental healthcare. Materials. 2010; 3:863-896.
  • Soliman, MSM, Mohsen CA, El-Mahallawi O, Abu-Eittah MRH. Effect of Different Cement Spaces on the Vertical Marginal Gap of Full Anatomical Zirconia Bridges. J Am Sci. 2015; 11(6):145-152.
  • Staehle HJ, Wohlrab T, Saure D, Wolff D, Frese C. A 6.5-year clinical follow-up of direct resin composite buildups in the posterior dentition: introduction of a new minimally invasive restorative method. J Dent. 2015; 43(10):1211-1217.
  • Stawarczyk B, Özcan M, Roos M, Trottmann A, Sailer I, Hämmerle CHF. Load-bearing capacity and failure types of anterior zirconia crowns veneered with overpressing and layering techniques. Dent Mater. 2011; 27:1045-1053.
  • Tan F. Bilgisayar ile tasarlanarak üretilen translüsent monolitik zirkonya ve çift tabakalı zirkonya restorasyonların klinik başarılarının değerlendirilmesi. Ege Ü Sağlık Bilimleri Enstitüsü, Uzmanlık Tezi, 2016, İzmir (Danışman: Doç. Dr. Muherrem Erhan Çömlekoğlu)
  • Triwatana P, Nagaviroj N, Tulapornchai C. Clinical performance and failures of zirconia-based fixed partial dentures: a review literature. J Adv Prosthodont. 2012: 4: 76-83.
  • Tsalouchou E, Cattell MJ, Knowles JC, Pittayachawan P, McDonald A. Fatigue and fracture properties of yttria partially stabilized zirconia crown systems. Dent Mater. 2008; 24:308-318.
  • Vagkopoulou T, Koutayas SO, Koidis P, Strub JR. Zirconia in dentistry: Part 1. Discovering the nature of an upcoming bioceramic. Eur J Esthet Dent. 2009; 4 :130-151.
  • Yihong L, Hailan F, Yiwang B, Yan Q, Ning X, Zhijian S. Fracture and interfacial delamination origins of bilayer ceramic composites for dental restorations. Journal of the European Ceramic Society. 2010; 30: 1297-1305.
  • Zhang Y, Lee JJ, Srikanth R, Lawn BR. Edge chipping and flexural resistance of monolithic ceramics. Dent Mater. 2013; 29: 1201-1208.
There are 50 citations in total.

Details

Primary Language Turkish
Subjects Dentistry
Journal Section Reviews
Authors

Elcin Keskin Özyer

Erkut Kahramanoğlu

Şükrü Can Akmansoy This is me

Yasemin Özkan

Publication Date June 28, 2019
Published in Issue Year 2019

Cite

APA Keskin Özyer, E., Kahramanoğlu, E., Akmansoy, Ş. C., Özkan, Y. (2019). ZİRKONYUM DESTEKLİ SABİT PROTETİK RESTORASYONLARDA KLİNİK BAŞARI DEĞERLENDİRME KRİTERLERİ. European Journal of Research in Dentistry, 3(1), 53-62. https://doi.org/10.35333/ERD.2019.14