Periferal Ossifiye Fibroma: Üç olgu sunumu
Year 2024,
Volume: 8 Issue: 3, 145 - 150, 31.12.2024
Suay Yağmur Ünal
,
Hakan Yülek
,
Gaye Keser
,
Filiz Mediha Namdar Pekiner
,
Selma Yaltkaya
Abstract
Periferal ossifiye fibroma (POF), ağırlıklı olarak kadınları etkileyen ve genellikle interdental papillada görülen reaktif bir yumuşak doku büyümesidir. Rengi soluk pembeden kiraz kırmızısına kadar değişir ve pürüzsüz bir yüzeye veya saplı geniş bir tabana sahip olabilir. Bu çalışmanın amacı üç farklı POF vakasını histopatolojik ve radyolojik incelemelerle değerlendirmek ve karşılaştırmaktır. Farklı yaşlarda iki kadın ve bir erkek hasta kliniğimize interdental papilla alanının anterior bölgesinde asemptomatik, yumuşak doku büyümeleri şikayeti ile geldi. Lezyonlar cerrahi olarak eksize edildi ve POF tanısını doğrulayan histopatolojik incelemeye gönderildi. POF'un etiyolojisi net olmamakla birlikte, plak, diş taşı, iyi oturmayan protezler ve uyumsuz diş restorasyonları gibi travma veya lokal irritasyonun POF gelişimini hızlandırdığı bilinmektedir. Diş hekimleri pyojenik granülom, fibroma ve periferal odontojenik fibroma gibi klinik ayırıcı tanıları göz önünde bulundurmalıdır.
References
- Agarwal, P., Chug, A., Kumar, S., & Jain, K. Palatal peripheral ossifying fibroma: A rare occurrence. International Journal of Health Sciences, 13(4), 2019, 63.
- Bhaskar, S.N., Jacoway, J.R. Peripheral fibroma and peripheral fibroma with calcification: report of 376 cases. Journal of the American Dental Association (1939), 73(6), 1966, 1312-1320.
- Buchner, A., Hansen, L.S. The histomorphologic spectrum of peripheral ossifying fibroma. Oral Surgery, Oral Medicine, Oral Pathology, 63, 1987, 452-461.
- Buchner, A., Shnaiderman-Shapiro, A., & Vered, M. Relative frequency of localized reactive hyperplastic lesions of the gingiva: a retrospective study of 1675 cases from Israel. Journal of Oral Pathology & Medicine, 39, 2010, 631-638.
- Cavalcante, I.L., et al. Peripheral ossifying fibroma: A 20-year retrospective study with focus on clinical and morphological features. Medicina Oral, Patología Oral y Cirugía Bucal, 27(5), 2022, e460.
- Chaitra, T.R., Singh, A.P., Jathar, P.N., & Kulkarni, A.U. Peripheral ossifying fibroma: dilemma in diagnosis. Case Reports, 2012, bcr1220115452.
- Cuisia, Z.E., Brannon, R.B. Peripheral ossifying fibroma—a clinical evaluation of 134 pediatric cases. Pediatric Dentistry, 23, 2001, 245-248.
- de Marcos, J.A.G., de Marcos, M.J.G., Rodríguez, S.A., Rodrigo, J.C., & Poblet, E. Peripheral ossifying fibroma: a clinical and immunohistochemical study of four cases. Journal of Oral Science, 52(1), 2010, 95-99.
- Franco-Barrera, M.J., Zavala-Cerna, M.G., Fernandez-Tamayo, R., et al. An update on peripheral ossifying fibroma: case report and literature review. Oral and Maxillofacial Surgery, 20, 2016, 1-7.
- Gulati, R., Khetarpal, S., Ratre, M.S., & Solanki, M. Management of massive peripheral ossifying fibroma using diode laser. Journal of Indian Society of Periodontology, 23(2), 2019, 177-180.
- Hunasgi, S., Koneru, A., Vanishree, M., & Manvikar, V. Assessment of reactive gingival lesions of oral cavity: A histopathological study. Journal of Oral and Maxillofacial Pathology, 21(1), 2017, 180.
- Kale, L., Khambete, N., Sodhi, S., & Sonawane, S. Peripheral ossifying fibroma: Series of five cases. Journal of Indian Society of Periodontology, 18(4), 2014, 527-530.
- Katanec, T., Budak, L., Brajdić, D., & Gabrić, D. Atypical peripheral ossifying fibroma of the mandible. Dentistry Journal, 10(1), 2022, 9.
- Kumar, S.K., Ram, S., Jorgensen, M.G., Shuler, C.F., & Sedghizadeh, P.P. Multicentric peripheral ossifying fibroma. Journal of Oral Science, 48(4), 2006, 239-243.
- Lazare, H., Peteiro, A., Perez Sayans, M., et al. Clinicopathological features of peripheral ossifying fibroma in a series of 41 patients. British Journal of Oral and Maxillofacial Surgery, 57, 2019, 1081-1085.
- Mergoni, G., Meleti, M., Magnolo, S., et al. Peripheral ossifying fibroma: a clinicopathologic study of 27 cases and review of the literature with emphasis on histomorphologic features. Journal of Indian Society of Periodontology, 19, 2015, 83-87.
- Neville, B.W., Damm, D.D., Allen, C.M., & Bouquot, J.E. Soft tissue tumors. In: Oral and maxillofacial pathology. 2nd ed. Philadelphia: Saunders, 2002.
- Parihar, A.S., et al. Peripheral ossifying fibroma: A diagnostic dilemma. Journal of Advanced Medical and Dental Sciences Research, 3(2), 2015, 162.
- Parsegian, K., Arce, R.M., Angelov, N. Surgical Periodontal Management of Peripheral Ossifying Fibroma: A Series of Three Cases. Case Reports in Dentistry, 2024(1), 2024, 3683561.
- Phore, S., et al. Peripheral ossifying fibroma: A rare case series. SRM Journal of Research in Dental Sciences, 7(2), 2016, 106-110.
- Shah, J.S., Sharma, S. Peripheral ossifying fibroma: An unusual presentation. International Journal of Oral Health Sciences, 8(1), 2018, 47-50.
- Shrestha, A., Keshwar, S., Jain, N., et al. Clinico-pathological profiling of peripheral ossifying fibroma of the oral cavity. Clinical Case Reports, 9, 2021, e04966.
- Sihavong, P., et al. Recurrence Peripheral Ossifying Fibroma: A Case Report. Asian Journal of Dental Sciences, 7(1), 2024, 165-169.
- Takagi, R., et al. A giant peripheral ossifying fibroma of the maxilla with extreme difficulty in clinical differentiation from malignancy: a case report and review of the literature. Journal of Medical Case Reports, 18(1), 2024, 220.
- Topçuoğlu, E.C., et al. Preserving periodontal tissue in the treatment of a large peripheral ossifying fibroma: a case study. Romanian Journal of Morphology and Embryology, 64(3), 2023, 427.
Peripheral Ossifying Fibroma: Series of Three Cases
Year 2024,
Volume: 8 Issue: 3, 145 - 150, 31.12.2024
Suay Yağmur Ünal
,
Hakan Yülek
,
Gaye Keser
,
Filiz Mediha Namdar Pekiner
,
Selma Yaltkaya
Abstract
Peripheral ossifying fibroma (POF) is a reactive soft tissue growth that predominantly affects females and usually seen on the interdental papilla. Its color ranges from pale pink to cherry red, and it might have a smooth surface or a broad base with pedunculation. This study’s purpose is to evaluate and compare three different POF cases with histopathological and radiological examination. Two female and one male patients of different ages came to our clinic with a complaint of asymptomatic, soft tissue growths in the anterior region of the interdental papillae area. The lesions were surgically excised and sent for histopathological examination which confirmed the diagnosis of POF. Even though the etiology of the POF is unclear, trauma or local irritation such as plaque, calculus, ill-fitting dental appliances, and poor-quality dental restorations are all known to precipitate the development of POF. Dentists should consider clinical differential diagnoses such as pyogenic granuloma, fibroma, and peripheral odontogenic fibroma.
References
- Agarwal, P., Chug, A., Kumar, S., & Jain, K. Palatal peripheral ossifying fibroma: A rare occurrence. International Journal of Health Sciences, 13(4), 2019, 63.
- Bhaskar, S.N., Jacoway, J.R. Peripheral fibroma and peripheral fibroma with calcification: report of 376 cases. Journal of the American Dental Association (1939), 73(6), 1966, 1312-1320.
- Buchner, A., Hansen, L.S. The histomorphologic spectrum of peripheral ossifying fibroma. Oral Surgery, Oral Medicine, Oral Pathology, 63, 1987, 452-461.
- Buchner, A., Shnaiderman-Shapiro, A., & Vered, M. Relative frequency of localized reactive hyperplastic lesions of the gingiva: a retrospective study of 1675 cases from Israel. Journal of Oral Pathology & Medicine, 39, 2010, 631-638.
- Cavalcante, I.L., et al. Peripheral ossifying fibroma: A 20-year retrospective study with focus on clinical and morphological features. Medicina Oral, Patología Oral y Cirugía Bucal, 27(5), 2022, e460.
- Chaitra, T.R., Singh, A.P., Jathar, P.N., & Kulkarni, A.U. Peripheral ossifying fibroma: dilemma in diagnosis. Case Reports, 2012, bcr1220115452.
- Cuisia, Z.E., Brannon, R.B. Peripheral ossifying fibroma—a clinical evaluation of 134 pediatric cases. Pediatric Dentistry, 23, 2001, 245-248.
- de Marcos, J.A.G., de Marcos, M.J.G., Rodríguez, S.A., Rodrigo, J.C., & Poblet, E. Peripheral ossifying fibroma: a clinical and immunohistochemical study of four cases. Journal of Oral Science, 52(1), 2010, 95-99.
- Franco-Barrera, M.J., Zavala-Cerna, M.G., Fernandez-Tamayo, R., et al. An update on peripheral ossifying fibroma: case report and literature review. Oral and Maxillofacial Surgery, 20, 2016, 1-7.
- Gulati, R., Khetarpal, S., Ratre, M.S., & Solanki, M. Management of massive peripheral ossifying fibroma using diode laser. Journal of Indian Society of Periodontology, 23(2), 2019, 177-180.
- Hunasgi, S., Koneru, A., Vanishree, M., & Manvikar, V. Assessment of reactive gingival lesions of oral cavity: A histopathological study. Journal of Oral and Maxillofacial Pathology, 21(1), 2017, 180.
- Kale, L., Khambete, N., Sodhi, S., & Sonawane, S. Peripheral ossifying fibroma: Series of five cases. Journal of Indian Society of Periodontology, 18(4), 2014, 527-530.
- Katanec, T., Budak, L., Brajdić, D., & Gabrić, D. Atypical peripheral ossifying fibroma of the mandible. Dentistry Journal, 10(1), 2022, 9.
- Kumar, S.K., Ram, S., Jorgensen, M.G., Shuler, C.F., & Sedghizadeh, P.P. Multicentric peripheral ossifying fibroma. Journal of Oral Science, 48(4), 2006, 239-243.
- Lazare, H., Peteiro, A., Perez Sayans, M., et al. Clinicopathological features of peripheral ossifying fibroma in a series of 41 patients. British Journal of Oral and Maxillofacial Surgery, 57, 2019, 1081-1085.
- Mergoni, G., Meleti, M., Magnolo, S., et al. Peripheral ossifying fibroma: a clinicopathologic study of 27 cases and review of the literature with emphasis on histomorphologic features. Journal of Indian Society of Periodontology, 19, 2015, 83-87.
- Neville, B.W., Damm, D.D., Allen, C.M., & Bouquot, J.E. Soft tissue tumors. In: Oral and maxillofacial pathology. 2nd ed. Philadelphia: Saunders, 2002.
- Parihar, A.S., et al. Peripheral ossifying fibroma: A diagnostic dilemma. Journal of Advanced Medical and Dental Sciences Research, 3(2), 2015, 162.
- Parsegian, K., Arce, R.M., Angelov, N. Surgical Periodontal Management of Peripheral Ossifying Fibroma: A Series of Three Cases. Case Reports in Dentistry, 2024(1), 2024, 3683561.
- Phore, S., et al. Peripheral ossifying fibroma: A rare case series. SRM Journal of Research in Dental Sciences, 7(2), 2016, 106-110.
- Shah, J.S., Sharma, S. Peripheral ossifying fibroma: An unusual presentation. International Journal of Oral Health Sciences, 8(1), 2018, 47-50.
- Shrestha, A., Keshwar, S., Jain, N., et al. Clinico-pathological profiling of peripheral ossifying fibroma of the oral cavity. Clinical Case Reports, 9, 2021, e04966.
- Sihavong, P., et al. Recurrence Peripheral Ossifying Fibroma: A Case Report. Asian Journal of Dental Sciences, 7(1), 2024, 165-169.
- Takagi, R., et al. A giant peripheral ossifying fibroma of the maxilla with extreme difficulty in clinical differentiation from malignancy: a case report and review of the literature. Journal of Medical Case Reports, 18(1), 2024, 220.
- Topçuoğlu, E.C., et al. Preserving periodontal tissue in the treatment of a large peripheral ossifying fibroma: a case study. Romanian Journal of Morphology and Embryology, 64(3), 2023, 427.