Yeme Bozukluklarının Kanser Oluşumundaki Rolü

Yıl 2022, Cilt: 9 Sayı: 2, 37 - 45, 27.12.2022

Betül Sukan , Gamze Akbulut

Öz

Beslenme ve yeme bozuklukları, başka herhangi bir sağlık durumuyla açıklanamayan, gelişimsel olarak uygun olmayan veya kültürel olarak onaylanmayan anormal yeme ve beslenme davranışlarını içermektedir. Yaygın olarak bilinen beslenme ve yeme bozuklukları; anoreksiya nervoza, bulimia nervoza ve tıkınırcasına yeme bozukluğudur. 2019 yılında Dünya çapında 55.5 milyon kişinin herhangi bir beslenme ve yeme bozukluğuna sahip olduğu tahmin edilmektedir.
Beslenme ve yeme bozuklukları, bireyleri kansere karşı çeşitli nedenlerden dolayı daha savunmasız hale getirebilmekte veya bazı kanserlere karşı koruyu olabilmektedir. Kanser ve yeme bozuklukları arasındaki ilişki son yıllarda dikkat çekmeye başlamıştır ancak bu konudaki çalışmalar oldukça sınırlı sayıdadır. Beslenme ve yeme bozukluklarının kanserin oluşumu üzerindeki etkisini anlamak, kanserin önlenmesi ve tedavisi için önem arz etmektedir.

Anahtar Kelimeler

yeme bozuklukları, kanser, anoreksiya nervoza, bulimiya nervoza, tıkınırcasına yeme bozukluğu

Kaynakça

• World Health Organization. ICD-11 for Mortality and Morbidity Statistics. 2020. Erişim Linki: https://icd.who.int/browse11/l-m/en#/http%3A%2F%2Fid.who.int%2Ficd%2Fentity%2F1673294767
• APA. Diagnostic and statistical manual of mental disorders. 5th. ed. Washington D.C.: American Psychiatric Association; 2013.
• Santomauro DF, Melen S, Mitchison D, Vos T, Whiteford H, Ferrari AJ. The hidden burden of eating disorders: an extension of estimates from the Global Burden of Disease Study 2019. The Lancet Psychiatry. 2021;8(4):320–8. Doi: 10.1016/S2215-0366(21)00040-7
• Smink FRE, Van Hoeken D, Hoek HW. Epidemiology of eating disorders: Incidence, prevalence and mortality rates. Curr Psychiatry Rep. 2012;14(4):406–14. Doi: 10.1016/S2215-0366(21)00040-7
• De Backer F. The Relation Between Eating Disorders and the Risk of Developing Cancer: A Systemic Review of the Literature [master’s thesis]. Ghent University; 2018.
• GLOBOCAN. Age standardized (World) incidence rates, breast, all ages. International Agency for Research on Cancer. 2020. Erişim Linki: https://gco.iarc.fr/today%0Ahttp://gco.iarc.fr/today
• Globocan. Turkey. International Agency for Research on Cancer. 2020 Erişim Linki: https://gco.iarc.fr/today/data/factsheets/populations/792-turkey-fact-sheets.pdf
• Michels KB, Ekbom A. Caloric Restriction and Incidence of Breast Cancer. J Am Med Assoc. 2004;291(10):1226–30. Doi: 10.1001/jama.291.10.1226
• Bens A, Papadopoulos FC, Pukkala E, Ekbom A, Gissler M, Mellemkjær L. Worse survival after breast cancer in women with anorexia nervosa. Breast Cancer Res Treat. 2018;168(2):495–500. Doi: 10.1007/s10549-017-4618-5
• Kimmel MC, Ferguson EH, Zerwas S, Bulik CM, Meltzer-Brody S. Obstetric and gynecologic problems associated with eating disorders. Int J Eat Disord. 2016;49(3):260–75. Doi: 10.1002/eat.22483
• Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. Lancet. 2019;393(10167):169–82. Doi: 10.1016/S0140-6736(18)32470-X
• Ding L, Liu C, Zhou QIN, Feng M, Wang J. Association of estradiol and HPV/HPV16 infection with the occurrence of cervical squamous cell carcinoma. Oncol Lett. 2019;17(3):3548–54.doi: 10.3892/ol.2019.10005
• Michels N, De Backer F, Dimakopoulou M, Mane K, Indave I, Huybrechts I. Eating disorders and the risk of developing cancer: a systematic review. Eat Weight Disord. 2021;26(4):1021–35. Doi: 10.1007/s40519-020-01020-4
• Tung KH, Wilkens LR, Wu AH, McDuffie K, Nomura AMY, Kolonel LN, et al. Effect of anovulation factors on pre- and postmenopausal ovarian cancer risk: Revisiting the incessant ovulation hypothesis. Am J Epidemiol.2005;161(4):321–9. Doi: https://doi.org/10.1093/aje/kwi046
• Langdon SP, Herrington CS, Hollis RL, Gourley C. Estrogen Signaling and Its Potential as a Target for Therapy in Ovarian Cancer. Cancers. 2020;12(6):1647. Doi: 10.3390/cancers12061647
• Mellemkjaer L, Papadopoulos FC, Pukkala E, Ekbom A, Gissler M, Christensen J, et al. Cancer incidence among patients with anorexia nervosa from Sweden, Denmark and Finland. PLoS One. 2015;10(5):e0128018. Doi: 10.1371/journal.pone.0128018
• Sekaninova N, Olexova LB, Visnovcova Z, Ondrejka I, Tonhajzerova I. Role of neuroendocrine, immune, and autonomic nervous system in anorexia nervosa-linked cardiovascular diseases. Int J Mol Sci. 2020;21(19):1–18. Doi: 10.3390/ijms21197302.
• Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–49. Doi: 10.3322/caac.21660
• O’Keeffe LM, Taylor G, Huxley RR, Mitchell P, Woodward M, Peters SAE. Smoking as a risk factor for lung cancer in women and men: A systematic review and meta-analysis. BMJ Open. 2018;8(10):e021611. Doi: 10.1136/bmjopen-2018-021611
• Zipfel S, Giel KE, Bulik CM, Hay P, Schmidt U. Anorexia nervosa: aetiology, assessment, and treatment. Lancet Psychiatry. 2015;2(12):1099-111. Doi: 10.1016/S2215-0366(15)00356-9
• de Jorge Martínez C, Rukh G, Williams MJ, Gaudio S, Brooks S, Schiöth HB. Genetics of anorexia nervosa: an overview of genome-wide association studies and emerging biological links. J Genet Genomics. 2022;49(1):1-12. Doi: 10.1016/j.jgg.2021.09.005
• Brewster DH, Nowell SL, Clark DN. Risk of oesophageal cancer among patients previously hospitalised with eating disorder. Cancer Epidemiol. 2015;39(3):313–20. Doi: 10.1016/j.canep.2015.02.009
• Matsha T, Stepien A, Blanco-Blanco E, Brink LT, Lombard CJ, van Rensburg S, et al. Self-induced vomiting - Risk for oesophageal cancer? South African Med J. 2006;96(3):209–12. Doi: 10.7196/SAMJ.1009
• Xi Y, Xu P. Global colorectal cancer burden in 2020 and projections to 2040. Transl Oncol. 2021;14(10):101174. Doi: 10.1016/j.tranon.2021.101174
• Citronberg JS, Hardikar S, Phipps A, Figueiredo JC, Newcomb P. Laxative type in relation to colorectal cancer risk. Ann Epidemiol. 2018;28(10):739–41. Doi: 10.1016/j.annepidem.2018.06.011
• Mason TB, Do B, Chu D, Belcher BR, Dunton GF, Lopez N V. Associations among affect, diet, and activity and binge-eating severity using ecological momentary assessment in a non-clinical sample of middle-aged fathers. Eat Weight Disord. 2022;27(2):543–51. Doi: 10.1007/s40519-021-01191-8
• Smith LA, O’Flanagan CH, Bowers LW, Allott EH, Hursting SD. Translating Mechanism-Based Strategies to Break the Obesity−Cancer Link: A Narrative Review. J Acad Nutr Diet. 2018;118(4):652–67. Doi: 10.1016/j.jand.2017.08.112
• He J, Cai Z, Fan X. Prevalence of binge and loss of control eating among children and adolescents with overweight and obesity: An exploratory meta-analysis. Int J Eat Disord. 2017;50(2):91–103. Doi: 10.1002/eat.22661
• Duncan AE, Ziobrowski HN, Nicol G. The Prevalence of Past 12-Month and Lifetime DSM-IV Eating Disorders by BMI Category in US Men and Women. Eur Eat Disord Rev. 2017;25(3):165–71. Doi: 10.1002/erv.2503
• Wassenaar E, Friedman J, Mehler PS. Medical Complications of Binge Eating Disorder. Psychiatr Clin North Am. 2019;42(2):275–86. Doi: 10.1016/j.psc.2019.01.010
• Morze J, Danielewicz A, Hoffmann G, Schwingshackl L. Diet Quality as Assessed by the Healthy Eating Index, Alternate Healthy Eating Index, Dietary Approaches to Stop Hypertension Score, and Health Outcomes: A Second Update of a Systematic Review and Meta-Analysis of Cohort Studies. J Acad Nutr Diet. 2020;120(12):1998-2031. Doi: 10.1016/j.jand.2020.08.076
• Latino-Martel P, Cottet V, Druesne-Pecollo N, Pierre FHF, Touillaud M, Touvier M, et al. Alcoholic beverages, obesity, physical activity and other nutritional factors, and cancer risk: A review of the evidence. Crit Rev Oncol Hematol. 2016;99:308–23. Doi: 10.1016/j.critrevonc.2016.01.002
• Chami R, Monteleone AM, Treasure J, Monteleone P. Stress hormones and eating disorders. Mol Cell Endocrinol. 2019;497:110349. Doi: 10.1016/j.mce.2018.12.009
• Soung NK, Kim BY. Psychological stress and cancer. J Anal Sci Technol. 2015;6(1):1–6. Doi: 10.1186/S40543-015-0070-5