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The effect of intradiscal injection of percutaneous radiopaque gel ethanol on pain in patients with lumbar disc herniation: Our clinical experience.

Year 2022, Volume: 3 Issue: 2, 130 - 137, 01.08.2022

Abstract

Introduction: Lumbar disc herniation (LDH); It is an important disease that is common in society and can cause socioeconomic problems. There are many treatment algorithms for LDH, including medical and surgical. Our aim in this study; To evaluate the clinical results of patients with LDH who did not benefit from conservative treatment after percutaneous intradiscal radiopaque gel ethanol (RGE) procedure in the light of the literature. Methods: A total of 44 levels of percutaneous intradiscal RGE were applied to 41 patients, 14 men and 27 women, hospitalized with the diagnosis of LDH. patients; Demographic characteristics, treatments they received, lumbar magnetic resonance imaging (MRI) taken 6 months later, visual analog scores (VAS) before and 6 months after percutaneous intradiscal RGE procedure, complications, side effects and patient satisfaction after the procedure were evaluated. Results: The VAS values of the patients were 8 before the procedure and 4.2 6 months after the procedure. A 47.5% reduction in pain was observed and these data were evaluated as statistically significant. When patients were asked about their satisfaction with the procedure after the percutaneous RGE procedure; 4 patients answered "poor", 13 patients "moderate", 13 patients "good" and 11 patients "excellent". The rate of those who were satisfied with the procedure was 90.2%, and these data were not considered statistically significant. Conclusion: As a result; Percutaneous intradiscal RGE procedure, in patients with a diagnosis of LDH and who did not benefit from conservative treatment; It can be a minimally invasive technique that reduces pain.

References

  • Barrero LH, Hsu YH, Terwedow H: Prevalence and physical determinants of low back pain in a rural Chinese population. Spine 31: 2728-2734, 2006
  • 2) Bellini M, Romano DG, Leonini S, Grazzini I, Tabano C, Ferrara M, Piu P, Monti L: A Cerase 2 Percutaneous injection of radiopaque gelified ethanol for the treatment of lumbar and cervical intervertebral disk herniations: experience and clinical outcome in 80 patients. AJNR Am J Neuroradiol 36: 600-605, 2015
  • 3) Borenstein DG: Chronic low back pain. Rheum Dis Clin North Am 22: 439-456, 1996
  • 4) Galluzzi KE: Management of neuropathic pain. J Am Osteopath Assoc 105: 119, 2005
  • 5) Gautam S, Rastogi V, Jain A, Singh AP: Comparative evaluation of oxygen-ozone therapy and combined use of oxygen-ozone therapy with percutaneous intradiscal radiofrequency thermocoagulation for the treatment of lumbar disc herniation. Pain Practice 11: 160-166, 2011
  • 6) Gazzeri R, Galarza M, Neroni M, Esposito S, Alfieri A: Fulminating septicemia secondary to oxygen-ozone therapy for lumbar disc herniation: case report. Spine 32: 121–123, 2007
  • 7) Gibson JN, Waddell G: Surgery for degenerative lumbar spondylosis: updated cochrane review. Spine 30: 2312–2320, 2005
  • 8) Ginanneschi F, Cervelli C, Milani P, Rossi A: Ventral and dorsal root injury after oxygen-ozone therapy for lumbar disk herniation. Surg Neurol 66: 619-621, 2006
  • 9) Goupille P, Mulleman D, Mammou S, Griffoul I, Valat JP: Percutaneous laser disc decompression for the treatment of lumbar disc herniation: a review. Semin Arthritis Rheum 37: 20–30, 2007
  • 10) Han HJ, Kim JY, Jang HY, Lee B, Yoon JH, Jang SK, Choi SH, Jeong SW: Fluoroscopic- guided intradiscal oxygen-ozone injection therapy for thoracolumbar intervertebral disc herniations in dogs. In Vivo 21: 609–613, 2007
  • 11) Heron J, Guimaraens L, Casasco A, Sola T, Cuellar H, Courtheoux P: Percutaneous treatment of lumbar intervertebral disk hernias with radiopaque gelified ethanol: a preliminary study. J Spinal Disord Tech 20: 526-532, 2007
  • 12) Kawaguchi Y, Matsui H, Gejo R, Tsuji H: Preventive measures of back muscle injury after posterior lumbar spine surgery in rats. Spine 23: 2282–2287, 1998
  • 13) Legrand E, Bouvard B, Audran M, Fournier D, Valat JP: Sciatica from disk herniation: medical treatment or surgery? Joint Bone Spine 74: 530–535, 2007
  • 14) Lo Giudice G, Valdi F, Gismondi M, Prosdocimo G, de Belvis V: Acute bilateral vitreo-retinal hemorrhages following oxygen-ozone therapy for lumbar disk herniation. Am J Ophthalmol 138:175-177, 2004
  • 15) Luijsterburg PA, Verhagen AP, Ostelo RW, van Os TA, Peul WC, Koes BW: Effectiveness of conservative treatments for the lumbosacral radicular syndrome: a systematic review. Eur Spine J 16: 881–899, 2007
  • 16) Martin DJ, Rad AE, Kallmes DF: Prevalence of extravertebral cement leakage after vertebroplasty: procedural documentation versus CT detection. Acta Radiol 53: 569–572, 2012
  • 17) Muralikuttan KP, Hamilton A, Kernohan WG, Mollan RA, Adair IV: A prospective randomized trial of chemonucleolysis and conventional disc surgery in single level lumbar disc herniation. Spine 17: 381–387, 1992
  • 18) Oláh M, Molnár L, Dobai J, Oláh C, Fehér J, Bender T: Evaluation of the efficacy of conservative therapies with clinical parameters and magnetic resonance ımaging in lumbar disc herniations. Rheumatol Int 28: 749-756, 2008
  • 29) Oliphant D: Safety of spinal manipulation in the treatment of lumbar disk herniations: A systematic review and risk assessment. J Manipulative Physiol Therap 27: 197-209, 2004
  • 20) Riquelme C, Musacchio M, Mont’Alverne F, Tournade A: Chemonucleolysis of lumbar disc herniation with ethanol. J Neuroradiol 28: 219–229, 2001
  • 21) Sharps LS, Isaac Z: Percutaneous disc decompression using nucleoplasty. Pain Physician 5: 121-126, 2002
  • 22) Sinan T, Sheikh M, Buric J, Dashti K, Al-Mukhaimi A: Percutaneous coblation nucleoplasty in patients with contained lumbar disc prolapse: 1 year follow-up in a prospective case series. Acta Neurochir Suppl 108: 107-112, 2011
  • 23) Theron J, Cuellar H, Sola T, Guimaraens L, Casasco A, Courtheoux P: Percutaneous treatment of cervical disk hernias using gelified ethanol. AJNR Am J Neuroradiol 31: 1454-1456, 2010
  • 24) Theron J, Guimaraens L, Casasco A, Sola T, Cuellar H, Courtheoux P: Percutaneous treatment of lumbar intervertebral disk hernias with radiopaque gelified ethanol: a preliminary study. J Spinal Disord Tech 20: 526–532, 2007
  • 25) Weber BR, Grob D, Dvorak J, Muntener M: Posterior surgical approach to the lumbar spine and its effect on the multifidus muscle. Spine 22: 1765–1772, 1997
  • 26) Zhu H, Zhou XZ, Cheng MH, Shen YX, Dong QR: The efficacy of coblation nucleoplasty for protrusion of lumbar intervertebral disc at a two-year follow-up. Int Orthop 35: 1677-1682, 2011

Lomber disk hernisi olan hastalarda intradiskal perkütan radyoopak jel etanol enjeksiyonunun ağrı üzerine etkisi: Klinik deneyimimiz

Year 2022, Volume: 3 Issue: 2, 130 - 137, 01.08.2022

Abstract

Giriş: Lomber disk hernisi (LDH); Toplumda sık görülen ve sosyoekonomik sorunlara neden olabilen önemli bir hastalıktır. LDH için tıbbi ve cerrahi dahil olmak üzere birçok tedavi algoritması vardır. Bu çalışmadaki amacımız; konservatif tedaviden fayda görmeyen LDH'li hastaların Perkütan intradiskal radyoopak jel etanol (RGE) işlemi sonrası klinik sonuçlarını literatür ışığında değerlendirmektir. Yöntemler: LDH tanısı ile yatırılan 14'ü erkek, 27'si kadın olmak üzere 41 hastaya toplam 44 seviyede perkütan intradiskal RGE uygulandı. Hastalar; demografik özellikler, aldıkları tedaviler, 6 ay sonra çekilen lomber manyetik rezonans görüntüleme (MRG), perkütan intradiskal RGE işlemi öncesi ve 6 ay sonraki görsel analog skorlamalar(VAS), komplikasyonlar, yan etkiler ve işlem sonrası hasta memnuniyeti açısından değerlendirildi. Bulgular: Hastaların VAS değerleri işlem öncesi 8, işlemden 6 ay sonra 4.2 olarak saptandı. Ağrıda %47.5'lik bir azalma olduğu izlendi ve bu veriler istatistiksel olarak anlamlı olarak değerlendirildi. Perkütan RGE işlemi sonrası hastalara işlemden memnuniyetleri sorulduğunda; 4 hasta "kötü", 13 hasta "orta", 13 hasta "iyi" ve 11 hasta "mükemmel" yanıtını vermiştir. İşlemden memnun olanların oranı %90,2 olup bu veriler istatistiksel olarak anlamlı kabul edilmedi. Sonuç: Sonuç olarak; Perkütan intradiskal RGE işlemi, LDH tanısı olan ve konservatif tedaviden fayda görmeyen hastalarda; ağrıları azalmasını sağlayan minimal invaziv bir teknik olabilir.

References

  • Barrero LH, Hsu YH, Terwedow H: Prevalence and physical determinants of low back pain in a rural Chinese population. Spine 31: 2728-2734, 2006
  • 2) Bellini M, Romano DG, Leonini S, Grazzini I, Tabano C, Ferrara M, Piu P, Monti L: A Cerase 2 Percutaneous injection of radiopaque gelified ethanol for the treatment of lumbar and cervical intervertebral disk herniations: experience and clinical outcome in 80 patients. AJNR Am J Neuroradiol 36: 600-605, 2015
  • 3) Borenstein DG: Chronic low back pain. Rheum Dis Clin North Am 22: 439-456, 1996
  • 4) Galluzzi KE: Management of neuropathic pain. J Am Osteopath Assoc 105: 119, 2005
  • 5) Gautam S, Rastogi V, Jain A, Singh AP: Comparative evaluation of oxygen-ozone therapy and combined use of oxygen-ozone therapy with percutaneous intradiscal radiofrequency thermocoagulation for the treatment of lumbar disc herniation. Pain Practice 11: 160-166, 2011
  • 6) Gazzeri R, Galarza M, Neroni M, Esposito S, Alfieri A: Fulminating septicemia secondary to oxygen-ozone therapy for lumbar disc herniation: case report. Spine 32: 121–123, 2007
  • 7) Gibson JN, Waddell G: Surgery for degenerative lumbar spondylosis: updated cochrane review. Spine 30: 2312–2320, 2005
  • 8) Ginanneschi F, Cervelli C, Milani P, Rossi A: Ventral and dorsal root injury after oxygen-ozone therapy for lumbar disk herniation. Surg Neurol 66: 619-621, 2006
  • 9) Goupille P, Mulleman D, Mammou S, Griffoul I, Valat JP: Percutaneous laser disc decompression for the treatment of lumbar disc herniation: a review. Semin Arthritis Rheum 37: 20–30, 2007
  • 10) Han HJ, Kim JY, Jang HY, Lee B, Yoon JH, Jang SK, Choi SH, Jeong SW: Fluoroscopic- guided intradiscal oxygen-ozone injection therapy for thoracolumbar intervertebral disc herniations in dogs. In Vivo 21: 609–613, 2007
  • 11) Heron J, Guimaraens L, Casasco A, Sola T, Cuellar H, Courtheoux P: Percutaneous treatment of lumbar intervertebral disk hernias with radiopaque gelified ethanol: a preliminary study. J Spinal Disord Tech 20: 526-532, 2007
  • 12) Kawaguchi Y, Matsui H, Gejo R, Tsuji H: Preventive measures of back muscle injury after posterior lumbar spine surgery in rats. Spine 23: 2282–2287, 1998
  • 13) Legrand E, Bouvard B, Audran M, Fournier D, Valat JP: Sciatica from disk herniation: medical treatment or surgery? Joint Bone Spine 74: 530–535, 2007
  • 14) Lo Giudice G, Valdi F, Gismondi M, Prosdocimo G, de Belvis V: Acute bilateral vitreo-retinal hemorrhages following oxygen-ozone therapy for lumbar disk herniation. Am J Ophthalmol 138:175-177, 2004
  • 15) Luijsterburg PA, Verhagen AP, Ostelo RW, van Os TA, Peul WC, Koes BW: Effectiveness of conservative treatments for the lumbosacral radicular syndrome: a systematic review. Eur Spine J 16: 881–899, 2007
  • 16) Martin DJ, Rad AE, Kallmes DF: Prevalence of extravertebral cement leakage after vertebroplasty: procedural documentation versus CT detection. Acta Radiol 53: 569–572, 2012
  • 17) Muralikuttan KP, Hamilton A, Kernohan WG, Mollan RA, Adair IV: A prospective randomized trial of chemonucleolysis and conventional disc surgery in single level lumbar disc herniation. Spine 17: 381–387, 1992
  • 18) Oláh M, Molnár L, Dobai J, Oláh C, Fehér J, Bender T: Evaluation of the efficacy of conservative therapies with clinical parameters and magnetic resonance ımaging in lumbar disc herniations. Rheumatol Int 28: 749-756, 2008
  • 29) Oliphant D: Safety of spinal manipulation in the treatment of lumbar disk herniations: A systematic review and risk assessment. J Manipulative Physiol Therap 27: 197-209, 2004
  • 20) Riquelme C, Musacchio M, Mont’Alverne F, Tournade A: Chemonucleolysis of lumbar disc herniation with ethanol. J Neuroradiol 28: 219–229, 2001
  • 21) Sharps LS, Isaac Z: Percutaneous disc decompression using nucleoplasty. Pain Physician 5: 121-126, 2002
  • 22) Sinan T, Sheikh M, Buric J, Dashti K, Al-Mukhaimi A: Percutaneous coblation nucleoplasty in patients with contained lumbar disc prolapse: 1 year follow-up in a prospective case series. Acta Neurochir Suppl 108: 107-112, 2011
  • 23) Theron J, Cuellar H, Sola T, Guimaraens L, Casasco A, Courtheoux P: Percutaneous treatment of cervical disk hernias using gelified ethanol. AJNR Am J Neuroradiol 31: 1454-1456, 2010
  • 24) Theron J, Guimaraens L, Casasco A, Sola T, Cuellar H, Courtheoux P: Percutaneous treatment of lumbar intervertebral disk hernias with radiopaque gelified ethanol: a preliminary study. J Spinal Disord Tech 20: 526–532, 2007
  • 25) Weber BR, Grob D, Dvorak J, Muntener M: Posterior surgical approach to the lumbar spine and its effect on the multifidus muscle. Spine 22: 1765–1772, 1997
  • 26) Zhu H, Zhou XZ, Cheng MH, Shen YX, Dong QR: The efficacy of coblation nucleoplasty for protrusion of lumbar intervertebral disc at a two-year follow-up. Int Orthop 35: 1677-1682, 2011
There are 26 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Research Articles
Authors

Oğuz Gürbüz This is me 0000-0002-1375-9011

Mehmet Beşir Sürme 0000-0002-1244-7892

Publication Date August 1, 2022
Published in Issue Year 2022 Volume: 3 Issue: 2

Cite

APA Gürbüz, O., & Sürme, M. B. (2022). The effect of intradiscal injection of percutaneous radiopaque gel ethanol on pain in patients with lumbar disc herniation: Our clinical experience. Eskisehir Medical Journal, 3(2), 130-137.
AMA Gürbüz O, Sürme MB. The effect of intradiscal injection of percutaneous radiopaque gel ethanol on pain in patients with lumbar disc herniation: Our clinical experience. Eskisehir Med J. August 2022;3(2):130-137.
Chicago Gürbüz, Oğuz, and Mehmet Beşir Sürme. “The Effect of Intradiscal Injection of Percutaneous Radiopaque Gel Ethanol on Pain in Patients With Lumbar Disc Herniation: Our Clinical Experience”. Eskisehir Medical Journal 3, no. 2 (August 2022): 130-37.
EndNote Gürbüz O, Sürme MB (August 1, 2022) The effect of intradiscal injection of percutaneous radiopaque gel ethanol on pain in patients with lumbar disc herniation: Our clinical experience. Eskisehir Medical Journal 3 2 130–137.
IEEE O. Gürbüz and M. B. Sürme, “The effect of intradiscal injection of percutaneous radiopaque gel ethanol on pain in patients with lumbar disc herniation: Our clinical experience”., Eskisehir Med J, vol. 3, no. 2, pp. 130–137, 2022.
ISNAD Gürbüz, Oğuz - Sürme, Mehmet Beşir. “The Effect of Intradiscal Injection of Percutaneous Radiopaque Gel Ethanol on Pain in Patients With Lumbar Disc Herniation: Our Clinical Experience”. Eskisehir Medical Journal 3/2 (August 2022), 130-137.
JAMA Gürbüz O, Sürme MB. The effect of intradiscal injection of percutaneous radiopaque gel ethanol on pain in patients with lumbar disc herniation: Our clinical experience. Eskisehir Med J. 2022;3:130–137.
MLA Gürbüz, Oğuz and Mehmet Beşir Sürme. “The Effect of Intradiscal Injection of Percutaneous Radiopaque Gel Ethanol on Pain in Patients With Lumbar Disc Herniation: Our Clinical Experience”. Eskisehir Medical Journal, vol. 3, no. 2, 2022, pp. 130-7.
Vancouver Gürbüz O, Sürme MB. The effect of intradiscal injection of percutaneous radiopaque gel ethanol on pain in patients with lumbar disc herniation: Our clinical experience. Eskisehir Med J. 2022;3(2):130-7.