Coenzyme Q10: Current Overview

Kadriye Erdoğan; Melahat Sedanur Macit; Nazlı Tunca Şanlıer; Yaprak Ustun

doi:10.46969/EZH.1002286

Review

Coenzyme Q10: Current Overview

Year 2022, Volume: 4 Issue: 2, 77 - 86, 30.06.2022

Kadriye Erdoğan , Melahat Sedanur Macit , Nazlı Tunca Şanlıer Yaprak Ustun

https://doi.org/10.46969/EZH.1002286

Abstract

Coenzyme Q10 (CoQ10) is a lipid-soluble component from benzoquinones. The oxidized form of Coenzyme Q10 is ubiquinone, and the reduced form is ubiquinol. As well to its endogenous synthesis, Coenzyme Q10 is also included in the diet. Dietary sources of CoQ10 are meat, poultry, fish, oil, and nuts. Coenzyme Q10 has an important role in energy metabolism in the mitochondria. It also protects the phospholipids, proteins, and DNA from oxidative damage in the membrane. It is stated that CoQ10 has several positive effects on diseases due to its antioxidant capacity. In recent years CoQ10 intake has become widespread. There are several studies investigating the usage and dosage of CoQ10 in diseases such as cardiovascular, neurological disease, diabetes, and reproductive endocrinology. In the present study, it was aimed to evaluate the CoQ10 and its possible health effects.

Keywords

Coenzyme Q10, dietary supplements, health, nutrition

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Koenzim Q10: Güncel Genel Bakış

Year 2022, Volume: 4 Issue: 2, 77 - 86, 30.06.2022

Kadriye Erdoğan , Melahat Sedanur Macit , Nazlı Tunca Şanlıer Yaprak Ustun

https://doi.org/10.46969/EZH.1002286

Abstract

Koenzim Q10 (CoQ10), benzokinonlardan elde edilen lipitte çözünür bir bileşendir. Koenzim Q10’un oksitlenmiş formu ubiquinonedir ve indirgenmiş formu ubiquinoldür. Koenzim Q10, endojen sentezinin yanı sıra diyete de dâhildir. CoQ10’un diyet kaynakları et, kümes hayvanları, balık, yağ ve fındıktır. Koenzim Q10 in mitokondride enerji metabolizmasında önemli görevleri bulunmaktadır. Ayrıca membrandaki oksidatif hasardan fosfolipitleri, proteinleri ve DNA’yı korur. CoQ10’un antioksidan kapasitesi nedeniyle hastalıklar üzerinde birçok olumlu etkisi olduğu belirtilmektedir. Son yıllarda CoQ10 alımı yaygınlaştı. CoQ10’un kardiyovasküler, nörolojik hastalıklar, diyabet, kadın hastalıkları ve doğum vb. pek çok hastalıkta kullanım ve kullanım miktarını araştıran çalışmalar bulunmaktadır. Bu yazıda CoQ10 un metabolizması, etki mekanizmaları ile sağlık üzerine olan etkilerinin değerlendirilmesi amacıyla yapılmıştır.

Keywords

Koenzim Q10, diyet takviyeleri, sağlık, beslenme

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Primary Language	English
Subjects	Obstetrics and Gynaecology
Journal Section	Review Article
Authors	Kadriye Erdoğan 0000-0002-8789-1875 Melahat Sedanur Macit 0000-0002-7480-1586 Nazlı Tunca Şanlıer This is me 0000-0002-5059-4594 Yaprak Ustun 0000-0002-1011-3848
Publication Date	June 30, 2022
Acceptance Date	June 28, 2022
Published in Issue	Year 2022 Volume: 4 Issue: 2

Cite

APA	Erdoğan, K., Macit, M. S., Şanlıer, N. T., Ustun, Y. (2022). Coenzyme Q10: Current Overview. Türk Kadın Sağlığı Ve Neonatoloji Dergisi, 4(2), 77-86. https://doi.org/10.46969/EZH.1002286
AMA	Erdoğan K, Macit MS, Şanlıer NT, Ustun Y. Coenzyme Q10: Current Overview. Türk Kadın Sağlığı ve Neonatoloji Dergisi. June 2022;4(2):77-86. doi:10.46969/EZH.1002286
Chicago	Erdoğan, Kadriye, Melahat Sedanur Macit, Nazlı Tunca Şanlıer, and Yaprak Ustun. “Coenzyme Q10: Current Overview”. Türk Kadın Sağlığı Ve Neonatoloji Dergisi 4, no. 2 (June 2022): 77-86. https://doi.org/10.46969/EZH.1002286.
EndNote	Erdoğan K, Macit MS, Şanlıer NT, Ustun Y (June 1, 2022) Coenzyme Q10: Current Overview. Türk Kadın Sağlığı ve Neonatoloji Dergisi 4 2 77–86.
IEEE	K. Erdoğan, M. S. Macit, N. T. Şanlıer, and Y. Ustun, “Coenzyme Q10: Current Overview”, Türk Kadın Sağlığı ve Neonatoloji Dergisi, vol. 4, no. 2, pp. 77–86, 2022, doi: 10.46969/EZH.1002286.
ISNAD	Erdoğan, Kadriye et al. “Coenzyme Q10: Current Overview”. Türk Kadın Sağlığı ve Neonatoloji Dergisi 4/2 (June 2022), 77-86. https://doi.org/10.46969/EZH.1002286.
JAMA	Erdoğan K, Macit MS, Şanlıer NT, Ustun Y. Coenzyme Q10: Current Overview. Türk Kadın Sağlığı ve Neonatoloji Dergisi. 2022;4:77–86.
MLA	Erdoğan, Kadriye et al. “Coenzyme Q10: Current Overview”. Türk Kadın Sağlığı Ve Neonatoloji Dergisi, vol. 4, no. 2, 2022, pp. 77-86, doi:10.46969/EZH.1002286.
Vancouver	Erdoğan K, Macit MS, Şanlıer NT, Ustun Y. Coenzyme Q10: Current Overview. Türk Kadın Sağlığı ve Neonatoloji Dergisi. 2022;4(2):77-86.

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