Centaurea balsamita Lam. ve Centaurea coronopifolia Lam. Türlerine Ait Farklı Ekstraktların Antimikrobiyal Aktivitesi

Öz

Centaurea türleri Türk geleneksel tıbbında çeşitli hastalıkların tedavisinde yaygın olarak kullanılmaktadır. Bu çalışmada, Centaurea balsamita Lam. and Centaurea coronopifolia Lam.türlerinin kloroform, etil asetat, aseton ve etanol ekstraktlarının çeşitli bakterilere karşı (Bacillus cereus ATCC 14579, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Escherichia coli ATCC 29988, Staphylococcus aureus ATCC 25923, Staphylococcus aureus ATCC 6538, Salmonella typhimurium ATCC 14028, Streptococcus salivarius RSHE 606) antimikrobiyal aktiviteleri broth mikrodilüsyon metodu kullanılarak araştırılmıştır. Sonuçlar, çalışmada test edilen mikroorganizmalara karşı bitki ekstraktlarının farklı ölçülerde antimikrobiyal aktiviteye sahip olduğunu göstermiştir. En yüksek antimikrobiyal aktiviteyi C. balsamita’nın kloroform ekstresi B. cereus’a karşı göstermiştir (0,039 µg/mL). Ayrıca, etanol ekstraktı dışında tüm ekstraktlar S. aureus suşlarına karşı yüksek antimikrobiyal aktivite göstermiştir (20 µg/mL).

Anahtar Kelimeler

• Antimikrobial aktivite
• Centaurea balsamita
• Centaurea coronopifolia
• ekstrakt

Antimicrobial Activity of Various Extracts of Centaurea balsamita Lam. And Centaurea coronopifolia Lam.

Abstract

Members of Centaurea have been widely used to treat various diseases in Turkish folk medicine. In this research, the antimicrobial activities of the chloroform, ethyl acetate, acetone, and ethanol extracts from Centaurea balsamita Lam. and Centaurea coronopifolia Lam. were investigated against some bacteria (Bacillus cereus ATCC 14579, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Escherichia coli ATCC 29988, Staphylococcus aureus ATCC 25923, Staphylococcus aureus ATCC 6538, Salmonella typhimurium ATCC 14028, Streptococcus salivarius RSHE 606) by microdilutation method. The results showed that the extracts have antimicrobial activity of different range against the test microorganisms used in this study. The chloroform extract of C. balsamita showed the highest antimicrobial activity against B. cereus strain (0,039 µg/mL). Also, all the extracts used in this study have significant antimicrobial activity against S. aureus strains (20 µg/mL), except the ethanol extracts which had lower activity.

Keywords

• Antimicrobial activity
• Centaurea balsamita
• Centaurea coronopifolia
• extract

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