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Yüksek kolesterollü diyetle beslenen ratlarda ginsengin bazı hematolojik parametreler üzerine etkisi

Year 2016, Volume: 32 Issue: 1, 48 - 51, 01.03.2016

Abstract

Amaç: Bu çalışmada kolesterolden zengin yemle beslenen
ratlarda ginsengin bazı hematolojik parametreler üzerine etkisinin
belirlenmesi amaçlandı.
Gereç ve Yöntem: Çalışmada sağlıklı 24 erkek Wistar Albino
rat kontrol (K), kolesterol (C) ve ginseng + kolesterol (GC)
olmak üzere 3 eşit gruba ayrıldı. K grubu standart rat yemi ile
beslenirken, C grubu %5 kolesterol içeren standart rat yemi,
GC grubu ise %5 kolesterol ve 1 g/kg ginseng kök tozu içeren
standart rat yemi ile 40 gün süreyle beslendi. Bütün hayvanlardan
çalışmanın sonunda antikoagulanlı kan örnekleri
toplandı. Bu kan örneklerinde alyuvar sayısı, akyuvar sayısı,
hemoglobin, hematokrit, granülosit, lenfosit, monosit, ortalama
alyuvar hacmi, ortalama alyuvar hemoglobin miktarı
ve ortalama alyuvar hemoglobin konsantrasyonu düzeyleri
otomatik hücre sayım cihazında belirlendi.
Bulgular: C grubu hemoglobin ve hematokrit düzeylerinin
kontrole göre önemli oranda düştüğü (P<0.05), GC grubunda
ise aynı parametrelerin C grubuna göre anlamlı olarak
yükseldiği belirlendi (P<0.05). Diğer parametreler açısından
gerek kolesterol gerekse ginseng uygulamasına bağlı değişikliklerin
istatistiksel olarak anlamlı olmadığı görüldü.
Öneri: Ginseng uygulamasının hiperkolesterolemik şartlarda
hematolojik parametrelerde meydana gelebilecek olumsuz
değişiklikleri düzeltebileceği ifade edilebilir.

The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet

Year 2016, Volume: 32 Issue: 1, 48 - 51, 01.03.2016

Abstract

Aim: The purpose of the present study was to examine the
effect of ginseng on some hematological parameters in rats
fed cholesterol-rich diet.
Materials and Methods: In this research, 24 male healthy
Wistar Albino rats were divided into three equal groups as
control (K), cholesterol (C) and ginseng + cholesterol (GC).
During the 40 days experiment, the K group received a standard
rat diet, whereas the C and GC groups were fed the same
standard diet containing 5% cholesterol and 5% cholesterol
+1 g/kg ginseng root powder, respectively. Anticoagulant
blood samples were taken from all animals at the end of the
study. In these blood samples, red and white blood cells, hemoglobin,
hematocrit, granulocytes, lymphocytes, monocytes,
mean red cell volume , mean corpuscular hemoglobin
and mean corpuscular hemoglobin concentration were measured
with hemacell counter.
Results: Hemoglobin and hematocrit levels of C group significantly
decreased compared to K group (P<0.05), while
the same parameters of GC group were found to be statically
higher than C group levels (P<0.05). In respect of the other
parameters, there was no important changes depend on ginseng
or/and cholesterol treatments.
Conclusion: It is stated that ginseng may improve the negative
effect of hypercholesterolemia on hematologic parameters.

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Details

Other ID JA28KF92TC
Journal Section Research
Authors

Deniz Uluışık This is me

Ercan Keskin This is me

Publication Date March 1, 2016
Published in Issue Year 2016 Volume: 32 Issue: 1

Cite

APA Uluışık, D., & Keskin, E. (2016). The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet. Eurasian Journal of Veterinary Sciences, 32(1), 48-51.
AMA Uluışık D, Keskin E. The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet. Eurasian J Vet Sci. March 2016;32(1):48-51.
Chicago Uluışık, Deniz, and Ercan Keskin. “The Effect of Ginseng on Some Hematological Parameters in Rats Fed Cholesterol-Rich Diet”. Eurasian Journal of Veterinary Sciences 32, no. 1 (March 2016): 48-51.
EndNote Uluışık D, Keskin E (March 1, 2016) The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet. Eurasian Journal of Veterinary Sciences 32 1 48–51.
IEEE D. Uluışık and E. Keskin, “The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet”, Eurasian J Vet Sci, vol. 32, no. 1, pp. 48–51, 2016.
ISNAD Uluışık, Deniz - Keskin, Ercan. “The Effect of Ginseng on Some Hematological Parameters in Rats Fed Cholesterol-Rich Diet”. Eurasian Journal of Veterinary Sciences 32/1 (March 2016), 48-51.
JAMA Uluışık D, Keskin E. The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet. Eurasian J Vet Sci. 2016;32:48–51.
MLA Uluışık, Deniz and Ercan Keskin. “The Effect of Ginseng on Some Hematological Parameters in Rats Fed Cholesterol-Rich Diet”. Eurasian Journal of Veterinary Sciences, vol. 32, no. 1, 2016, pp. 48-51.
Vancouver Uluışık D, Keskin E. The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet. Eurasian J Vet Sci. 2016;32(1):48-51.