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Koyunlarda Tarantula cubensis alkolik ekstraktının (Theranekron®) serum tiyobarbitürik asit reaktif ürünlerine etkisi

Year 2014, Volume: 30 Issue: 2, 68 - 71, 01.06.2014

Abstract

Amaç: Mevcut araştırmanın amacı koyunlarda Tarantula cubensis alkolik ekstraktının serum tiyobarbitürik asit reaktif ürünlerine etkisini değerlendirmektir. Ayrıca hematolojik ve biyokimyasal parametrelere etkilerini değerlendirmektir. Gereç ve Yöntem: Altı adet Akkaraman koyuna tek doz (6 mL/koyun, SC) Tarantula cubensis alkolik ekstraktı uygulandı. Kan örnekleri uygulamadan hemen önce (0 saat, kontrol) ve sonraki 2, 4, 8, 12, 24 ve 48. saatlerde alındı. Serum tiyobarbitürik asit reaktif ürünleri düzeyi ELISA okuyucusunda belirlendi. Biyokimyasal ve hematolojik parametreler sırası ile otoanalizör ve kan hücresi sayım cihazında belirlendi. Bulgular: Tarantula cubensis alkolik ekstraktı koyunlarda serum tiyobarbitürik asit reaktif ürünleri düzeyini belirgin şekilde düşürdü, ancak istatistiki fark belirlenmedi. Ayrıca ekstratın hematolojik ve biyokimyasal parametrelere olumsuz etkisi belirlenmedi. Öneri: Tarantula cubensis alkolik ekstraktının antioksidan etkinlik gösterebileceği ve kısa süreli değerlendirilmesi dikkate alındığında koyunlarda güvenli olabileceği ifade edilebilir.

References

  • Albay MK, Şahinduran Ş, Kale M, Karakurum MÇ, Sezer K, 2010. Sığırların mavi dil hastalığında ağız lezyonlarının tedavisinde tarantula cubensis ekstraktının etkinliği. Kafkas Univ Vet Fak Derg, 16, 593-596.
  • Anonim 2014. http://www.richter-pharma.at/producttheranekron-d6_301.htm. Erişim tarihi: 15.03.2014
  • Çayırlı M, Açıkgöz G, 2013. Vitamin E ve deri. Turk J Dermatol, 6, 87-90.
  • Doğan F, 2011. Veteriner hekimliğinde farmakovijilans. Eurasian J Vet Sci, 27, 19-25.
  • Duz E, Icen H, Arserrim NB, Cakmak F, Bakir B, Ersin Uysal, 2012. Comparison of classic, theranekron and classic-plus theranekron treatment on the foot and mouth disease lesions in cattle in Van, Diyarbakir and Ankara Regions in Turkey. J Anim Vet Adv, 11, 3258-3261.
  • Gültiken N, Vural MR, 2007. The effect of tarantula cubensis extract applied in pre and post-operative period of canine mammary tumors. JIVS, 2, 13-23.
  • Kaçar C, Zonturlu AK, Oral H, Yıldız S, Arı UÇ, 2007. İneklerde erken purperal dönemde theranekron® uygulamalarının uterus involusyonu ve vaginal akıntı üzerine etkisi. Kafkas Üniv Vet Fak Derg, 13, 11-15.

Effect of alcoholic extract of Tarantula cubensis (Theranekron®) on serum thiobarbituric acid-reactive species concentrations in sheep

Year 2014, Volume: 30 Issue: 2, 68 - 71, 01.06.2014

Abstract

Aim: The aim of the current research was to evaluate the effect of alcoholic extract of Tarantula cubensis on serum thiobarbituric acid-reactive species concentrations in sheep. Furthermore, it’s effect on the hematological and biochemical values were determined. Materials and Methods: Six Akkaraman sheep were administered single dose (6 mL/sheep, SC) of alcoholic extract of Tarantula cubensis. Blood samples were obtained before (0 hour, control) and 2, 4, 8, 12, 24 and 48 hours after administration. Serum thiobarbituric acid-reactive species concentrations were measured by ELISA reader. The concentrations of biochemical and hemogram values were measured by autoanalyzer and blood cell counter, respectively.Results: Alcoholic extract of Tarantula cubensis dramatically decreased on serum thiobarbituric acid-reactive species concentrations in sheep but no statistically significant. In addition, it had no any negative effect on the hematological and biochemical values. Conclusions: It is stated that alcoholic extract of Tarantula cubensis may cause antioxidant effect and it may be accepted safe in sheep when evaluation of short time duration was considered.

References

  • Albay MK, Şahinduran Ş, Kale M, Karakurum MÇ, Sezer K, 2010. Sığırların mavi dil hastalığında ağız lezyonlarının tedavisinde tarantula cubensis ekstraktının etkinliği. Kafkas Univ Vet Fak Derg, 16, 593-596.
  • Anonim 2014. http://www.richter-pharma.at/producttheranekron-d6_301.htm. Erişim tarihi: 15.03.2014
  • Çayırlı M, Açıkgöz G, 2013. Vitamin E ve deri. Turk J Dermatol, 6, 87-90.
  • Doğan F, 2011. Veteriner hekimliğinde farmakovijilans. Eurasian J Vet Sci, 27, 19-25.
  • Duz E, Icen H, Arserrim NB, Cakmak F, Bakir B, Ersin Uysal, 2012. Comparison of classic, theranekron and classic-plus theranekron treatment on the foot and mouth disease lesions in cattle in Van, Diyarbakir and Ankara Regions in Turkey. J Anim Vet Adv, 11, 3258-3261.
  • Gültiken N, Vural MR, 2007. The effect of tarantula cubensis extract applied in pre and post-operative period of canine mammary tumors. JIVS, 2, 13-23.
  • Kaçar C, Zonturlu AK, Oral H, Yıldız S, Arı UÇ, 2007. İneklerde erken purperal dönemde theranekron® uygulamalarının uterus involusyonu ve vaginal akıntı üzerine etkisi. Kafkas Üniv Vet Fak Derg, 13, 11-15.
There are 7 citations in total.

Details

Other ID JA62GK49JG
Journal Section Research
Authors

Burak Dik This is me

Ayşe Er This is me

Orhan Çorum This is me

Publication Date June 1, 2014
Published in Issue Year 2014 Volume: 30 Issue: 2

Cite

APA Dik, B., Er, A., & Çorum, O. (2014). Effect of alcoholic extract of Tarantula cubensis (Theranekron®) on serum thiobarbituric acid-reactive species concentrations in sheep. Eurasian Journal of Veterinary Sciences, 30(2), 68-71.
AMA Dik B, Er A, Çorum O. Effect of alcoholic extract of Tarantula cubensis (Theranekron®) on serum thiobarbituric acid-reactive species concentrations in sheep. Eurasian J Vet Sci. June 2014;30(2):68-71.
Chicago Dik, Burak, Ayşe Er, and Orhan Çorum. “Effect of Alcoholic Extract of Tarantula Cubensis (Theranekron®) on Serum Thiobarbituric Acid-Reactive Species Concentrations in Sheep”. Eurasian Journal of Veterinary Sciences 30, no. 2 (June 2014): 68-71.
EndNote Dik B, Er A, Çorum O (June 1, 2014) Effect of alcoholic extract of Tarantula cubensis (Theranekron®) on serum thiobarbituric acid-reactive species concentrations in sheep. Eurasian Journal of Veterinary Sciences 30 2 68–71.
IEEE B. Dik, A. Er, and O. Çorum, “Effect of alcoholic extract of Tarantula cubensis (Theranekron®) on serum thiobarbituric acid-reactive species concentrations in sheep”, Eurasian J Vet Sci, vol. 30, no. 2, pp. 68–71, 2014.
ISNAD Dik, Burak et al. “Effect of Alcoholic Extract of Tarantula Cubensis (Theranekron®) on Serum Thiobarbituric Acid-Reactive Species Concentrations in Sheep”. Eurasian Journal of Veterinary Sciences 30/2 (June 2014), 68-71.
JAMA Dik B, Er A, Çorum O. Effect of alcoholic extract of Tarantula cubensis (Theranekron®) on serum thiobarbituric acid-reactive species concentrations in sheep. Eurasian J Vet Sci. 2014;30:68–71.
MLA Dik, Burak et al. “Effect of Alcoholic Extract of Tarantula Cubensis (Theranekron®) on Serum Thiobarbituric Acid-Reactive Species Concentrations in Sheep”. Eurasian Journal of Veterinary Sciences, vol. 30, no. 2, 2014, pp. 68-71.
Vancouver Dik B, Er A, Çorum O. Effect of alcoholic extract of Tarantula cubensis (Theranekron®) on serum thiobarbituric acid-reactive species concentrations in sheep. Eurasian J Vet Sci. 2014;30(2):68-71.