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Bir Golden hamsterda (Mesocricetus auratus) spontan lenfoma

Year 2013, Volume: 29 Issue: 1, 50 - 52, 01.03.2013

Abstract

Mevcut klinik olguda, bir Golden hamsterda spontan lenfoma
olgusu tartışıldı. Veteriner hastanesine iki haftadır süren kilo
kaybı, iştahsızlık, ishal ve servical lenf nodüllerinde belirgin
şişkinlikle karakterize erkek hamster getirildi. Fiziksel
muayenede yaygın lenfadenomegali ve dehidrasyon belirlendi.
Periton içi hidrokortizon ve dekstroz uygulamaları yapılmasına
rağmen hasta öldü. Nekropside bütün süperfisial lenf
yumrularında önemli büyümeler gözlendi. Ancak mezenterik,
dalak ve karaciğer lenf yumrularının normal olduğu gözlendi.
Diseke edilen lenf nodülleri merkezinde nekrozlar tespit edildi.
Histopatolojik incelemede orta derecede mitotik indeksli büyük
veziküler çekirdek içeren lenfoid hücreler belirlendi. Mevcut
bulgular diffuz büyük B hücreli lenfomalı non-Hodgkin tanısını
koydurdu. Laboratuvar hayvanlarında deneysel lenfomalar
yapılmasına rağmen hamsterlarda spontan lenfomalar çok nadir
gözlenmektedir. Mevcut klinik rapor spontan lenfomanın klinik
ve histopatalojik varlığını tanımlandı.

Spontaneous lymphoma in a Golden hamster (Mesocricetus auratus)

Year 2013, Volume: 29 Issue: 1, 50 - 52, 01.03.2013

Abstract

In this clinical report, occurrence of a spontaneous lymphoma
was discussed in a Golden hamster. Male hamster was referred
to the veterinary hospital with a history of anorexia, diarrhea,
prominent swelling of cervical lymph nodes and progressive
weight loss since two weeks ago. During physical examination
generalized lymphadenomegaly and severe dehydration was
seen. Intraperitoneal dextrose and hydrocortisone was injected
but the patient died. In necropsy, significant enlargements of all
superficial lymph nodes were observed but the mesenteric lymph
nodes, spleen, and liver were seemed normal. Dissected lymph
nodes showed necrotized center. Histopathologic examination
revealed lymphoid cells containing large vesicular nuclei with
evident nucleoli which showed moderate mitotic index. On the
basis of these findings, a definitive diagnosis of non-Hodgkin
diffuse large B-ceIl lymphoma was made. Experimentally induced
lymphomas have been reported in laboratory animals; however,
spontaneously occurring lymphomas have been infrequently
described in hamsters. This clinical report describes the clinical
and histopathological aspects of a spontaneous lymphoma.

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Details

Other ID JA69HJ22KZ
Journal Section Case Report
Authors

Reza Kheirandish This is me

Baharak Akhtardanesh This is me

Nasrin Askari This is me

Publication Date March 1, 2013
Published in Issue Year 2013 Volume: 29 Issue: 1

Cite

APA Kheirandish, R., Akhtardanesh, B., & Askari, N. (2013). Spontaneous lymphoma in a Golden hamster (Mesocricetus auratus). Eurasian Journal of Veterinary Sciences, 29(1), 50-52.
AMA Kheirandish R, Akhtardanesh B, Askari N. Spontaneous lymphoma in a Golden hamster (Mesocricetus auratus). Eurasian J Vet Sci. March 2013;29(1):50-52.
Chicago Kheirandish, Reza, Baharak Akhtardanesh, and Nasrin Askari. “Spontaneous Lymphoma in a Golden Hamster (Mesocricetus Auratus)”. Eurasian Journal of Veterinary Sciences 29, no. 1 (March 2013): 50-52.
EndNote Kheirandish R, Akhtardanesh B, Askari N (March 1, 2013) Spontaneous lymphoma in a Golden hamster (Mesocricetus auratus). Eurasian Journal of Veterinary Sciences 29 1 50–52.
IEEE R. Kheirandish, B. Akhtardanesh, and N. Askari, “Spontaneous lymphoma in a Golden hamster (Mesocricetus auratus)”, Eurasian J Vet Sci, vol. 29, no. 1, pp. 50–52, 2013.
ISNAD Kheirandish, Reza et al. “Spontaneous Lymphoma in a Golden Hamster (Mesocricetus Auratus)”. Eurasian Journal of Veterinary Sciences 29/1 (March 2013), 50-52.
JAMA Kheirandish R, Akhtardanesh B, Askari N. Spontaneous lymphoma in a Golden hamster (Mesocricetus auratus). Eurasian J Vet Sci. 2013;29:50–52.
MLA Kheirandish, Reza et al. “Spontaneous Lymphoma in a Golden Hamster (Mesocricetus Auratus)”. Eurasian Journal of Veterinary Sciences, vol. 29, no. 1, 2013, pp. 50-52.
Vancouver Kheirandish R, Akhtardanesh B, Askari N. Spontaneous lymphoma in a Golden hamster (Mesocricetus auratus). Eurasian J Vet Sci. 2013;29(1):50-2.