AFLATOKSİN VE GLUKOMANNANIN TAVŞANLARDA BAZİ HEMATOLOJİK PARAMETRELER ÜZERİNE ETKİLERİ

Year 2007, Volume: 23 Issue: 2, 47 - 50, 01.06.2007

Nurcan Dönmez Banu Atalay Deniz Fedai

Abstract

Keywords

Aflatoksin, glukomannan, tavşan, hematolojik parametreler

The Effects of Aflatoxin and Glucomannan on some Hematological Parameters in Rabbits

Abstract

The aim ol this study was to evaluate the effects of atlatoxin and glukomannan on some hematological parameters.
In the study, 40 New Zelland rabbits were used and the rabbits were seperated equally to four groups as
control (K), glucomannan (G), glucomannan+ allatoksin (AF) and aflatoxin (A). At the end of the (10 week) experiment,
erythrocyte and haemoglobin levels decreased significantly (p

Keywords

Aflatoxin, glucomannan, rabbit, hematological parameters

References

• Abdel-Wahhab, MA, Nada, SA, Khalil, FA (2002) Physiological and toxicological responses in rats fed aflatoxin- contaminated diet with or without sorbent materials. Animal Feed ScL Thec. 97: 209-219.
• Arawind, K.L., Patil, V.S., Devegowda, G., Umakantha, B., Ganpule S.P. (2003) elficiacy of esterified glucomannan to counteraet mycotoxicosis in naturally contaminated feed on performance and serum biochemical, haematological parameters in broilers. Poultry SeL82: 571·576.
• Basmacıoğlu, H., u z H., Ergul M., Çöl R, Birdane Y.O. (2005) Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology 'n broilers exposed to aflatoxin. Czech. J. Anim. ScL 50, 1, 31- 39.
• Clark, J.D., Greene, C.E., Calpin, J.P., Hatch, RC. and Jain, A.V. (1986) Induced Aflatoxicosis in Rabbits: Blood coagulation Defects. Toxicology and Applied Pharmacology. 86, 353-361.
• Çelik, I., Demet, Ö., Dönmez, H.H., Oğuz, H., Boydak, M. (1996) Aflatoksin ve Aflatoksin Bağlayıcısı Olan Polivinil Polipirolidon (PVPP) Verilen Broylerlerde Peritoneal Makrofajlann Fagositik ve Mikrobisidal Aktivitelerinin Belirlenmesi. Veteriner Bilimleri Dergisi. 12,1,145·151.
• Çelik,I., Oğuz H., Demet, Ö., Boydak, M., Dönmez, H.H., Sur, E., Nizamlıoğlu F. (2oo0)a Embryotoxicity Assay ol Aflatoxin Produced by Aspergillus paraslticus NRRL 2999. British Poultry Science, 41,401-409.
• Çelik,I., Oğuz, H., Demet, Ö., Dönmez, H.H., Boydak, M. Sur, E. (2000)b Elficacy of Polyvinylpolypyrrolidone in Reducing the Immunotoxicity ol Aflatoxin in Growing Broilers. British Poultry Science, 41, 430-439.
• Diaz, D.E, Hagler, W.M., Hopkins, BA, Whitlow, L.W. (2002) Aflatoxin Binders i: In vitro Binding Assay For AIlatoxin B1 by Several Potential Sequestering Agenls. Mycopathologia, 156, 223-226.
• Eras ıan, G., Liman, B.C., Güçlü, B.K., Atasever., Koç, A.N., Beyaz, L. (2004) Evaluation of aflatoxin toxicity in Japanes quails given various doses of hidrated sodium calcium :.Juminosilicate. Bull. Vet. Inst. Pullawy. 48: 511- 517.S
• Harvey, RB., Kubera, L.F., Phillips, T.D., Cornier, D.E., Ellisade, M.H., Hull, W.E. (1991) Dimunition ol aflatoxin toxicity to growing lambs by dietary supplementation with HSCAS. Am. J. Vet. Res., 52: 152-156.
• Kaneko, J.J. (1989) Clinical Chemistry of Domostic Animals, 4th Edition, Academic Pres, San Diego, CA. Keçeci, T., Oğuz H., Kurtoğ lu, V., Demet, Ö. (1998) EI· fects of polyvinylpolyprolidone, synthelic zeolite and bentonite on serum biochemical and haematological characters ol broiler chickens during aflatoxicosis. British Poultry Science. 39, 452-458.
• Oğuz, H., Keçeci, T., Birdane, Y.O., Önder, F., Kurtoğ lu, V. (2000) Effecl of clinoptilolile on serum biochemical and haematological characters ol brel ler chickens during atlatoxicosis. Research in Veterinary Science. 69, 89-93.
• Raju, MVLN., Devegowda, ·G. (2000) Influence ol esterified glucomannan on performance and organ morphology, serum biochemistry and haematology in broilers exposed to individual and combined mycotoxicosis (atlatoxin, ochratoxin and T·2 toxin). Br. Poult. Sci. 41, 640- 650.
• Santin, E., Paulilla, A.C. Maiorka, A., Nakaghi, L.S.O., Macari, M., Silva, A.V.F. Alessi, A.C. (2003) Evaluation ol the efficacy of Saccharomyces Cerevisiae Cell Wall to Ameliorate the Toxic Effects of Aflatoxin in Broilers. Int. J. poultry Sci. 2, 341·344.
• Van Vleet, J.F., Ferrans, V.J. (1992) Etiological Factors and Pathologic Alterations in Selonium- Vitamin E Deficiency and Excess in Animals and Humans. Biol.Trace Elem. Res., 33, 1-12.
• Yousef, tAI., Salem, MH., Kamel, KI, Hassan, GA., EINouty, FO. (2003) Influence ol ascorbic acid suppemen t:ı ti o n on the haomatological and elinical biochern.stry parameters of male rabbits exposed to allatoxin Bl. J. Environ SCi. Health B. 38 (2),193·209.