The influence of citric acid on the absorbtion of chlortetracycline from the alimentary tract in the Broiler chickens

Year 1987, Volume: 3 Issue: 1, 253 - 258, 01.03.1987

Ahmet Acet Mursayettin Eksen Zafer Durgun.

Abstract

Plasma and tissues concentrations were determined by
fluorimetric method, after administering the chlortetracycline orally to
the Broiler chickens. It was found that the most drug residues were in
the liver and kidney. It was observed that citric acid has increased the
chlortetracycline absorption in the alimentary tract. The emission maxima
of the chlortetracycline was 500 nm and excitation maxima was at 400 nm.
The chlortetracycline residues which were determined in the plasma and
tissues were observed between 0,007-0,046 ug/g.

BROYLER PİLİÇLERİNDE SİTRİK ASİDİN KLORTETRASİKLİNİN SİNDİRİM SİSTEMİNDEN EMİLMESİNE ETKİSİ

Abstract

Klortetrasiklin Brayler piliçlerine ağızdan verildikten sonra
plazma ve doku yoğunlukları fluorimetrik metot ile tayin edildi. İlaç kalıntılarının
en fazla karaciğer ve böbrekte olduğu belirlendi. Sitrik asitin,
klortetrasiklinin sindirim kanalından emilimini arttırdığı görüldü. Klortetrasiklinin
emisyon maksiması 500 nm ve eksitasyon maksiması 400 nın'­
ye ayarlandı. Plazma ve dokularda belirlenen klortetrasiklin kalıntıları­
nın 0,007-0,046 lJ.g/g arasınlda olduğu görüldü.