Case Report
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Year 2016, , 77 - 79, 04.03.2016
https://doi.org/10.18621/eurj.2016.2.1.77

Abstract

References

  • Bringhurst FR, Demay MB, Kronenberg HM.Hormones and disorders of mineral metabolism. In:Williams Textbook Of Endocrinology tenth edition. Philadelphia: Saunders, 2003:1303-73.
  • Wysolmersky J.J, Insogna KL. The parathyroid glands, hypercalcemia and hypocalcemia. In: Goldman L, Ausiello D. Cecil textbook of medicine 23rd edition. Philadelphia: Saunders, 2008:1897-906.
  • Breslau NA, Zerwekh JE. Relationship of estrogen and pregnancy to calcium homeostasis in pseudohypoparathyroidism. J Clin Endocrinol Metab. 1986 Jan;62(1):45-51.
  • Schnatz PF, Curry SL. Primary hyperparathyroidism in pregnancy: evidence-based management. Obstet Gynecol Surv. 2002 Jun;57(6):365-76.
  • Norman J, Politz D, Politz L. Hyperparathyroidism during pregnancy and the effect of rising calcium on pregnancy loss: a call for earlier intervention. Clin Endocrinol (Oxf). 2009 Jul;71(1):104-9.
  • Carella MJ, Gossain VV. Hyperparathyroidism and pregnancy: case report and review. J Gen Intern Med. 1992 Jul-Aug;7(4):448-53.
  • Kelly TR. Primary hyperparathyroidism during pregnancy. Surgery. 1991 Dec;110(6):1028-33.
  • Croom RD 3rd, Thomas CG Jr. Primary hyperparathyroidism during pregnancy. Surgery. 1984 Dec;96(6):1109-18.
  • Rajala B, Abbasi RA, Hutchinson HT, Taylor T. Acute pancreatitis and primary hyperparathyroidism in pregnancy: treatment of hypercalcemia with magnesium sulfate. Obstet Gynecol. 1987 Sep;70(3 Pt 2):460-2.
  • Montoro MN, Collea JV, Mestman JH. Management of hyperparathyroidism in pregnancy with oral phosphate therapy. Obstet Gynecol. 1980 Apr;55(4):431-4.
  • Herrera-Martínez AD, Bahamondes-Opazo R, Palomares-Ortega R, Muñoz-Jiménez C, Gálvez-Moreno MA, Quesada Gómez JM. Primary hyperparathyroidism in pregnancy: a two-case report and literature review. Case Rep Obstet Gynecol. 2015;2015:171828.
  • Horjus C, Groot I, Telting D, van Setten P, van Sorge A, Kovacs CS, et al. Cinacalcet for hyperparathyroidism in pregnancy and puerperium. J Pediatr Endocrinol Metab. 2009 Aug;22(8):741-9.
  • Som M, Stroup JS. Primary hyperparathyroidism and pregnancy. Proc (Bayl Univ Med Cent). 2011 Jul;24(3):220-3.
  • Dochez V, Ducarme G. Primary hyperparathyroidism during pregnancy. Arch Gynecol Obstet. 2015 Feb;291(2):259-63.

A pregnant woman with primary hyperparathyroidism: a case report

Year 2016, , 77 - 79, 04.03.2016
https://doi.org/10.18621/eurj.2016.2.1.77

Abstract

Primary hyperparathyroidism is diagnosed with an increase of calcium levels and a decrease in phosphorus levels. Primary hyperparathyroidism is a rare condition in pregnancy. Calcium levels tend to be low in pregnant women, and high levels of calcium can point a primary hyperparathyroidism. Here, we report an original case of a pregnant woman with primary hyperparathyroidism who was fully healed after the surgery. A 30-year-old pregnant women (10th gestational week), admitted to the endocrinology department for management of thyrotoxicosis, when high calcium levels (11.8 mg/dL) were found in the laboratory tests. The parathyroid hormone level was 135 pg/ml.  Ultrasound imaging revealed a parathyroid adenoma (12x7x27mm). She had maintained high calcium levels despite the medical treatment, for this reason, she had surgery in the second trimester. Our case was diagnosed early due to early recognition of calcium elevation. The mother and the foetus had not any complication. Pregnant women tend to have low calcium levels hence if a hypercalcemia situation appears in pregnant women; primary hyperparathroidism has to be suspected.

References

  • Bringhurst FR, Demay MB, Kronenberg HM.Hormones and disorders of mineral metabolism. In:Williams Textbook Of Endocrinology tenth edition. Philadelphia: Saunders, 2003:1303-73.
  • Wysolmersky J.J, Insogna KL. The parathyroid glands, hypercalcemia and hypocalcemia. In: Goldman L, Ausiello D. Cecil textbook of medicine 23rd edition. Philadelphia: Saunders, 2008:1897-906.
  • Breslau NA, Zerwekh JE. Relationship of estrogen and pregnancy to calcium homeostasis in pseudohypoparathyroidism. J Clin Endocrinol Metab. 1986 Jan;62(1):45-51.
  • Schnatz PF, Curry SL. Primary hyperparathyroidism in pregnancy: evidence-based management. Obstet Gynecol Surv. 2002 Jun;57(6):365-76.
  • Norman J, Politz D, Politz L. Hyperparathyroidism during pregnancy and the effect of rising calcium on pregnancy loss: a call for earlier intervention. Clin Endocrinol (Oxf). 2009 Jul;71(1):104-9.
  • Carella MJ, Gossain VV. Hyperparathyroidism and pregnancy: case report and review. J Gen Intern Med. 1992 Jul-Aug;7(4):448-53.
  • Kelly TR. Primary hyperparathyroidism during pregnancy. Surgery. 1991 Dec;110(6):1028-33.
  • Croom RD 3rd, Thomas CG Jr. Primary hyperparathyroidism during pregnancy. Surgery. 1984 Dec;96(6):1109-18.
  • Rajala B, Abbasi RA, Hutchinson HT, Taylor T. Acute pancreatitis and primary hyperparathyroidism in pregnancy: treatment of hypercalcemia with magnesium sulfate. Obstet Gynecol. 1987 Sep;70(3 Pt 2):460-2.
  • Montoro MN, Collea JV, Mestman JH. Management of hyperparathyroidism in pregnancy with oral phosphate therapy. Obstet Gynecol. 1980 Apr;55(4):431-4.
  • Herrera-Martínez AD, Bahamondes-Opazo R, Palomares-Ortega R, Muñoz-Jiménez C, Gálvez-Moreno MA, Quesada Gómez JM. Primary hyperparathyroidism in pregnancy: a two-case report and literature review. Case Rep Obstet Gynecol. 2015;2015:171828.
  • Horjus C, Groot I, Telting D, van Setten P, van Sorge A, Kovacs CS, et al. Cinacalcet for hyperparathyroidism in pregnancy and puerperium. J Pediatr Endocrinol Metab. 2009 Aug;22(8):741-9.
  • Som M, Stroup JS. Primary hyperparathyroidism and pregnancy. Proc (Bayl Univ Med Cent). 2011 Jul;24(3):220-3.
  • Dochez V, Ducarme G. Primary hyperparathyroidism during pregnancy. Arch Gynecol Obstet. 2015 Feb;291(2):259-63.
There are 14 citations in total.

Details

Subjects Health Care Administration
Journal Section Case Reports
Authors

Goknur Yorulmaz

Nur Kebapci This is me

Kevser Onbasi

Belgin Efe This is me

Aysen Akalin This is me

Publication Date March 4, 2016
Submission Date October 19, 2015
Acceptance Date December 4, 2015
Published in Issue Year 2016

Cite

AMA Yorulmaz G, Kebapci N, Onbasi K, Efe B, Akalin A. A pregnant woman with primary hyperparathyroidism: a case report. Eur Res J. March 2016;2(1):77-79. doi:10.18621/eurj.2016.2.1.77

e-ISSN: 2149-3189 


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