A rare cause of gallbladder perforation: Burkitt's lymphoma

Year 2019, , 920 - 925, 04.09.2019

Musa Zorlu

https://doi.org/10.18621/eurj.432284

Abstract

Although the perforation of gallbladder rarely
occurs, it is a high-risk and life-threatening condition. High rates of
mortality and morbidity are associated with late diagnosis. Burkitt’s lymphoma
is a disease, which starts in B-cells and develops with leukemia and extranodal
involvement. Involvement of gallbladder wall is a very rare location of
extranodal lymphomas. In this case, a 68-year-old woman with severe pain in the
left arm referred to our outpatients’ clinic where anti-HCV (+), leukocytosis,
elevated sedimentation rate, and thrombocytopenia were found in her initial
tests. On the basis of these findings, further tests were performed and she was
diagnosed with Burkitt’s lymphoma. She had acute abdomen and  gallbladder perforation was detected by
radiologic study. Urgent laparotomy was performed and she subsequently
underwent cholecystectomy and drain insertion. Postoperative septic shock
developed and she died due to multiple organ dysfunction syndrome. The
determined diagnosis was described as gallbladder wall perforation associated
with Burkitt’s lymphoma infiltration in the pathology report. It is very
important for the clinicians to take into the consideration that a rare cause
of gallbladder perforation is Burkitt’s lymphoma and it has an aggressive
postoperative clinical course. 

Keywords

Gallbladder perforation, Burkitt’s lymphoma

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