Sinonasal sarcoidosis: a case report

Year 2020, , 260 - 264, 04.05.2020

Selma Erdoğan Düzcü , Serap Köybaşı Şanal

https://doi.org/10.18621/eurj.510830

Abstract

Sarcoidosis is an idiopathic
and multisystemic chronic disease characterized by non-caseating granulomas.
Sinonasal sarcoidosis may be seen in an isolated form or related to a
multisystemic disease. A 48-year-old female patient visited the otolaryngology
department with complaints of headache and nasal obstruction for two years. The
physical examination revealed a saddling on the nose, and crusted fragile
mucosa was observed bilaterally in nasal endoscopy. Paranasal CT showed
invasion of the right orbita. In chest
X-ray, there was bilateral hilar enlargement, and lung biopsy revealed
non-caseating granulomas. A bilateral endoscopic sinus surgery was applied to
the patient. Upon histopathological demonstration of multiple non-caseating
granulomas in the specimen, the diagnosis of sinonasal sarcoidosis was made.
The patient responded well to the following steroid treatment. Although rare,
sarcoidosis should be taken into consideration in differential diagnosis of sinonasal
diseases. 

Keywords

sarcoidosis, sinonasal involvement, non-caseating granulomas

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