Effect of transdermally applied nitroglycerin or lidocaine before transradial coronary angiography on procedure success and complications

Year 2024, EARLY ONLINE, 1 - 7

Nurullah Uslu , Cihan Aydın , Aykut Demirkıran , Hüseyin Aykaç , Şeref Alpsoy

https://doi.org/10.18621/eurj.1480019

Abstract

Objective: We investigated the effect of transdermal nitroglycerin or lidocaine application on puncture time, number, and complications in patients who underwent transradial coronary angiography.

Methods: Patients with topical saline applied to the radial artery before the procedure were designated as Group 1 (n=59), those with topical nitrate were designated as Group 2 (n=43), and those with topical lidocaine were designated as Group 3 (n=40). The groups' puncture time, number, and complication rates were compared.

Results: While our average puncture time was 142±122 seconds in all patients, this time was measured as 171±131 seconds in Group 1, 88±48 seconds in Group 2, and 157±146 seconds in Group 3 (P=0.021). During the procedure, radial artery spasm was observed in 15.2% of patients in Group 1, 6.9% in Group 2, and 12.5% in Group 3 (P=0.043). Radial artery occlusion was seen in 8% of patients in Group 1, and 2.5% in Group 3, while it was not observed at all in the nitrate-applied group (P=0.041).

Conclusion: The topical application of nitroglycerin before transradial angiography is a feasible strategy to reduce radial puncture time and number, facilitate trans-radial catheterization, and decrease the incidence of radial artery spasm and occlusion.

Keywords

Transradial coronary angiography, transdermal, nitroglycerin, lidocaine, spasm

Ethical Statement

Tekirdağ Namık Kemal University Ethics Committee

Project Number

2020.36.02.14

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