Research Article
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Year 2025, EARLY ONLINE, 1 - 6
https://doi.org/10.18621/eurj.1669429

Abstract

References

  • 1. Clark GW, Pope SM, Jaboori KA. Diagnosis and treatment of seborrheic dermatitis. Am Fam Physician. 2015;91(3):185-190.
  • 2. Celik MS, Arpa A. Evaluation of epicardial fat tissue thickness in patients with seborrheic dermatitis. Arch Dermatol Res. 2025;317(1):364. doi: 10.1007/s00403-025-03909-5.
  • 3. Imamoglu B, Hayta SB, Guner R, Akyol M, Ozcelik S. Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis. Arch Med Sci Atheroscler Dis. 2016;1(1):e158-161. doi: 10.5114/amsad.2016.65075.
  • 4. Linder D, Dreiher J, Zampetti A, Sampogna F, Cohen AD. Seborrheic dermatitis and hypertension in adults: a cross-sectional study. J Eur Acad Dermatol Venereol. 2014;28(11):1450-1455. doi: 10.1111/jdv.12310.
  • 5. Tosun M, Yasak Güner R, Akyol M. Investigation of the relationship between inflammatory blood parameters and seborrheic dermatitis. J Cosmet Dermatol. 2022;21(10):5111-5115. doi: 10.1111/jocd.14984.
  • 6. Mangia M, D'Andrea E, Cecchetto A, Beccari R, Mele D, Nistri S. Current and Clinically Relevant Echocardiographic Parameters to Analyze Left Atrial Function. J Cardiovasc Dev Dis. 2024;11(8):241. doi: 10.3390/jcdd11080241.
  • 7. Hoit BD. Left atrial size and function: role in prognosis. J Am Coll Cardiol. 2014;63(6):493-505. doi: 10.1016/j.jacc.2013.10.055.
  • 8. Tsang TS, Barnes ME, Gersh BJ, et al. Prediction of risk for first age-related cardiovascular events in an elderly population: the incremental value of echocardiography. J Am Coll Cardiol. 2003;42(7):1199-1205. doi: 10.1016/s0735-1097(03)00943-4.
  • 9. Ahmeti A, Bytyçi FS, Bielecka-Dabrowa A, Bytyçi I, Henein MY. Prognostic value of left atrial volume index in acute coronary syndrome: A systematic review and meta-analysis. Clin Physiol Funct Imaging. 2021;41(2):128-135. doi: 10.1111/cpf.12689.
  • 10. Atas H, Kepez A, Bozbay M, et al. Assessment of left atrial volume and function in patients with psoriasis by using real time three-dimensional echocardiography. Wien Klin Wochenschr. 2015;127(21-22):858-863. doi: 10.1007/s00508-015-0817-4.
  • 11. Aksan G, Nar G, Soylu K, et al. Assessment of atrial electromechanical delay and left atrial mechanical functions in patients with psoriasis vulgaris. Echocardiography. 2015;32(4):615-622. doi: 10.1111/echo.12706.
  • 12. Simsek H, Sahin M, Akyol A, et al. Increased risk of atrial and ventricular arrhythmia in long-lasting psoriasis patients. ScientificWorldJournal. 2013;2013:901215. doi: 10.1155/2013/901215.
  • 13. Krajewski PK, Matusiak Ł, Ständer S, Thaçi D, Szepietowski JC, Zirpel H. Risk of cardiovascular disorders in hidradenitis suppurativa patients: a large-scale, propensity-matched global retrospective cohort study. Int J Dermatol. 2024;63(6):799-805. doi: 10.1111/ijd.17186.
  • 13. Sánchez-Díaz M, Salvador-Rodríguez L, Cuenca-Barrales C, Arias-Santiago S, Molina-Leyva A. Exploring the role of systemic immune-inflammation index and neutrophil-lymphocyte ratio in cardiovascular risk stratification for patients with hidradenitis suppurativa: A cross-sectional study. J Dermatol. 2022;49(12):1238-1244. doi: 10.1111/1346-8138.16558.
  • 15. Juhl CR, Miller IM, Jemec GB, Kanters JK, Ellervik C. Hidradenitis suppurativa and electrocardiographic changes: a cross-sectional population study. Br J Dermatol. 2018;178(1):222-228. doi: 10.1111/bjd.15778.
  • 16. Mitter SS, Shah SJ, Thomas JD. A Test in Context: E/A and E/e' to Assess Diastolic Dysfunction and LV Filling Pressure. J Am Coll Cardiol. 2017;69(11):1451-1464. doi: 10.1016/j.jacc.2016.12.037.
  • 17. Bülbül Şen B, Ekiz Ö, Rifaioğlu EN, et al. Assessment of subclinical left ventricular dysfunction in patients with psoriasis by speckle tracking echocardiography: A Speckle Tracking Study. Int J Dermatol. 2016;55(2):158-164. doi: 10.1111/ijd.12703.
  • 18. Baykal Selçuk L, Şahin M, Aydemir B, Aksu Arıca D, Yaylı S. Effects of interleukin-12/23 inhibitors and interleukin-17 inhibitors on myocardial functions in patients with severe psoriasis. Turkderm-Turk Arch Dermatol Venereol. 2024;58(4):112-116. doi: 10.4274/turkderm.galenos.2024.20737.
  • 19. Mikeladze B, Zhvania N, Nikolaishvili G. E/e' Ratio as a Predictor of In-Hospital Complications and Clinical Outcomes of Acute Myocardial Infarction. Cureus. 2024;16(8):e66795. doi: 10.7759/cureus.66795.

Left atrial volume index in patients with seborrheic dermatitis

Year 2025, EARLY ONLINE, 1 - 6
https://doi.org/10.18621/eurj.1669429

Abstract

Objectives: Seborrheic dermatitis is a chronic inflammatory skin condition that primarily affects the scalp, face, and body folds. Emerging research indicates a potential link between seborrheic dermatitis and cardiac parameters. This study aims to further investigate this relationship.

Methods: Fifty individuals diagnosed with seborrheic dermatitis who presented to the dermatology outpatient clinic were included, alongside a control group of healthy participants (n=30) matched by age and sex. Echocardiographic assessments were carried out for both groups, and the data were recorded using standardized forms.

Results: The left atrial volume index (LAVI) was recorded as 28.3±1.24 in seborrheic dermatitis patients and 26.2±1.47 in the control group, with this difference reaching statistical significance (P<0.001). Similarly, the E/e' ratio was found to be 8.52±0.777 in the patient group and 7.16±0.706 in the control group, demonstrating a statistically significant difference (P<0.001).

Conclusions: The observed increase in LAVI and E/e' ratio among seborrheic dermatitis patients suggests a potential association with an elevated risk of cardiovascular disease and atrial fibrillation. Given these findings, long-term monitoring of individuals with seborrheic dermatitis may be warranted.

Ethical Statement

This study was approved by the Diyarbakır Gazi Yaşargil and Research Hospital Clinical Research Ethics Committee. (Date: 22.11.2024, Number: 267). The study was conducted in accordance with the principles of the Helsinki Declaration. Furthermore, it was conducted in accordance with the guidelines of good clinical practice. Informed consent was obtained from all individual participants included in the study.

References

  • 1. Clark GW, Pope SM, Jaboori KA. Diagnosis and treatment of seborrheic dermatitis. Am Fam Physician. 2015;91(3):185-190.
  • 2. Celik MS, Arpa A. Evaluation of epicardial fat tissue thickness in patients with seborrheic dermatitis. Arch Dermatol Res. 2025;317(1):364. doi: 10.1007/s00403-025-03909-5.
  • 3. Imamoglu B, Hayta SB, Guner R, Akyol M, Ozcelik S. Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis. Arch Med Sci Atheroscler Dis. 2016;1(1):e158-161. doi: 10.5114/amsad.2016.65075.
  • 4. Linder D, Dreiher J, Zampetti A, Sampogna F, Cohen AD. Seborrheic dermatitis and hypertension in adults: a cross-sectional study. J Eur Acad Dermatol Venereol. 2014;28(11):1450-1455. doi: 10.1111/jdv.12310.
  • 5. Tosun M, Yasak Güner R, Akyol M. Investigation of the relationship between inflammatory blood parameters and seborrheic dermatitis. J Cosmet Dermatol. 2022;21(10):5111-5115. doi: 10.1111/jocd.14984.
  • 6. Mangia M, D'Andrea E, Cecchetto A, Beccari R, Mele D, Nistri S. Current and Clinically Relevant Echocardiographic Parameters to Analyze Left Atrial Function. J Cardiovasc Dev Dis. 2024;11(8):241. doi: 10.3390/jcdd11080241.
  • 7. Hoit BD. Left atrial size and function: role in prognosis. J Am Coll Cardiol. 2014;63(6):493-505. doi: 10.1016/j.jacc.2013.10.055.
  • 8. Tsang TS, Barnes ME, Gersh BJ, et al. Prediction of risk for first age-related cardiovascular events in an elderly population: the incremental value of echocardiography. J Am Coll Cardiol. 2003;42(7):1199-1205. doi: 10.1016/s0735-1097(03)00943-4.
  • 9. Ahmeti A, Bytyçi FS, Bielecka-Dabrowa A, Bytyçi I, Henein MY. Prognostic value of left atrial volume index in acute coronary syndrome: A systematic review and meta-analysis. Clin Physiol Funct Imaging. 2021;41(2):128-135. doi: 10.1111/cpf.12689.
  • 10. Atas H, Kepez A, Bozbay M, et al. Assessment of left atrial volume and function in patients with psoriasis by using real time three-dimensional echocardiography. Wien Klin Wochenschr. 2015;127(21-22):858-863. doi: 10.1007/s00508-015-0817-4.
  • 11. Aksan G, Nar G, Soylu K, et al. Assessment of atrial electromechanical delay and left atrial mechanical functions in patients with psoriasis vulgaris. Echocardiography. 2015;32(4):615-622. doi: 10.1111/echo.12706.
  • 12. Simsek H, Sahin M, Akyol A, et al. Increased risk of atrial and ventricular arrhythmia in long-lasting psoriasis patients. ScientificWorldJournal. 2013;2013:901215. doi: 10.1155/2013/901215.
  • 13. Krajewski PK, Matusiak Ł, Ständer S, Thaçi D, Szepietowski JC, Zirpel H. Risk of cardiovascular disorders in hidradenitis suppurativa patients: a large-scale, propensity-matched global retrospective cohort study. Int J Dermatol. 2024;63(6):799-805. doi: 10.1111/ijd.17186.
  • 13. Sánchez-Díaz M, Salvador-Rodríguez L, Cuenca-Barrales C, Arias-Santiago S, Molina-Leyva A. Exploring the role of systemic immune-inflammation index and neutrophil-lymphocyte ratio in cardiovascular risk stratification for patients with hidradenitis suppurativa: A cross-sectional study. J Dermatol. 2022;49(12):1238-1244. doi: 10.1111/1346-8138.16558.
  • 15. Juhl CR, Miller IM, Jemec GB, Kanters JK, Ellervik C. Hidradenitis suppurativa and electrocardiographic changes: a cross-sectional population study. Br J Dermatol. 2018;178(1):222-228. doi: 10.1111/bjd.15778.
  • 16. Mitter SS, Shah SJ, Thomas JD. A Test in Context: E/A and E/e' to Assess Diastolic Dysfunction and LV Filling Pressure. J Am Coll Cardiol. 2017;69(11):1451-1464. doi: 10.1016/j.jacc.2016.12.037.
  • 17. Bülbül Şen B, Ekiz Ö, Rifaioğlu EN, et al. Assessment of subclinical left ventricular dysfunction in patients with psoriasis by speckle tracking echocardiography: A Speckle Tracking Study. Int J Dermatol. 2016;55(2):158-164. doi: 10.1111/ijd.12703.
  • 18. Baykal Selçuk L, Şahin M, Aydemir B, Aksu Arıca D, Yaylı S. Effects of interleukin-12/23 inhibitors and interleukin-17 inhibitors on myocardial functions in patients with severe psoriasis. Turkderm-Turk Arch Dermatol Venereol. 2024;58(4):112-116. doi: 10.4274/turkderm.galenos.2024.20737.
  • 19. Mikeladze B, Zhvania N, Nikolaishvili G. E/e' Ratio as a Predictor of In-Hospital Complications and Clinical Outcomes of Acute Myocardial Infarction. Cureus. 2024;16(8):e66795. doi: 10.7759/cureus.66795.
There are 19 citations in total.

Details

Primary Language English
Subjects Dermatology
Journal Section Original Articles
Authors

Mehmet Semih Çelik 0000-0002-3378-0619

Abdulkadir Arpa 0000-0002-6077-0416

Early Pub Date July 29, 2025
Publication Date
Submission Date April 3, 2025
Acceptance Date July 17, 2025
Published in Issue Year 2025 EARLY ONLINE

Cite

AMA Çelik MS, Arpa A. Left atrial volume index in patients with seborrheic dermatitis. Eur Res J. Published online July 1, 2025:1-6. doi:10.18621/eurj.1669429

e-ISSN: 2149-3189 


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