Year 2017,
Volume: 3 Issue: 2, 101 - 105, 04.07.2017
Shishir Ram Shetty
,
Sura Ali Ahmed Fuoad Al-bayati
Mohammed Said Hamed
Hossam Abdelatty Eid Abdemagyd
References
- [1] Bhardwaj R, Chaudhary K, Kaur S, Gupta R, Kamal R, Kumar M. Lycopene in oral health. Indian J Oral Sci 2013;4:125-9.
- [2] Anand D. The response of oral submucous fibrosis to lycopene - A carotenoid antioxidant: A clinicopathological study. J Clin Diagn Res 2011;5:882-8.
- [3] Danaraddi S, Koneru A, Hunasgi S, Ramalu S, Vanishree M. Natural ways to prevent and treat oral cancer. J Oral Res Rev 2014;6:34-9.
- [4] Armstron GA, Hearst JE. Carotenoids 2: Genetics and molecular biology of carotenoid pigment biosynthesis. Faseb J 1996;10:228-37.
- [5] Singh BG, Prasanth P. Lycopene- secondary suppreser for cancer. Int J Res Pharm Chem 2012;2:984-95.
- [6] Bohm F, Tinkler JH, Truscott TG. Carotenoids protect against cellmembrane damage by the nitrogen dioxide radical. Nat Med 1995;1:98-9.
- [7] Palozza P, Catalano A, Simone R, Cittadini A. Lycopene as a guardian of redox signalling. Acta Biochim Pol 2012;59:21-5.
- [8] Stahl W, Junghans A, De Boer B, Driomina ES, Briviba K, Sies H. Carotenoid mixtures protect multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein. FEBS Lett 1998;427:305-8.
- [9] Smedman AEM, Smith C. Lycopene protects DNA damage in colon cells induced by MNNG and H2O2. Anticancer Res Abs 1995;82:1656-60.
- [10] Bertram JS, Pung A, Churrby M. Review of carotenoids inhibiting malignant transformation by MCA or X-ray radiation. Carcinogenesis 1991;12:671-8.
- [11] Heber D, Lu QY. Overview of mechanisms of action of lycopene. Exp Biol Med 2002;227:920-3.
- [12] Singh M, Krishanappa R, Bagewadi A, Keluskar V. Efficacy of oral lycopene in the treatment of oral leukoplakia. Oral Oncol 2004;40:591-6.
- [13] Livny O, Kaplan I, Reifen R, Polak-Charcon S, Madar Z, Schwartz B. Lycopene inhibits proliferation and enhances gap-junction communication of KB-1 human oral tumor cells. J Nutr 2002;132:3754-9.
- [14] Gowda BB, Yathish TR , Sankappa SP, Naik KH, Somayaji P, Anand D. The response of oral submucous fibrosis to lycopene – A carotenoid antioxidant: A clinicopathological study. J Clin Diag Res 2011;5:882-8.
- [15] Palozza P, Simone RE, Catalano A, Mele MC. Tomato lycopene and lung cancer prevention: From experimental to human studies. Cancers (Basel) 2011;3:2333-57.
- [16] Liu C, Russell RM, Wang XD. Lycopene supplementation prevents smoke-induced changes in p53, p53 phosphorylation, cell proliferation, and apoptosis in the gastric mucosa of ferrets. J Nutr 2006;136:106-11.
- [17] Shetti N, Patil R. Antioxidants: its beneficial role against health damaging free radical. World J SciTechnol 2011;1:46-51.
- [18] Reddy ES. Role of antioxidants in precancerous lesions. J Ind Den Assc 2011;3:99-101.
- [19] Gowda BB, Yathish TR, Sinhasan SP, Kumar NH, Purushotham S, Anand D. The response of oral submucous fibrosis to lycopene-A carotenoid antioxidant: A clinicopathological study. J Clin Diagn Res 2011;5:882-8.
- [20] Schierle J, Bretzel, W, Buhler I, Faccin N, Hess D, Steiner K, et al. Content and isomeric ratio of lycopene in food and human blood plasma. Food Chem 1997;59:459-65.
- [21] Halloway DE, Yang M, Paganga G, Rice-Evans CA, BramleyPM. Isomerization of dietary lycopene during assimilation and transport in plasma. Free Radical Res 2000;32:93-102.
- [22] Re R, Fraser PD, Long M, Bramley PM, Rice-Evans C. Isomerization of lycopene in the gastric milieu. Biochem Biophys Res Commun 2001;281:576-81.
- [23] Boileau TWM, Boileau AC, Erdman JW. Bioavailability of all trans and cis-isomers of lycopene. Exp Biol Med 2002;227:914-9.
- [24] Richelle M, Bortlik K, Liardet S, Hager, C, Lambelet P, Baur M, et al. A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste. J Nutr 2002;132:404-8.
- [25] Agarwal S, Rao AV. Tomatolycopene and low-density lipoproteinoxidation: a human dietary intervention study. Lipids 1998;33: 981-4.
- [26] Kumar A, Bagewadi A, Keluskar V, Singh M. Efficacy of lycopene in the management of oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:207-13.
- [27] Karemore TV, Motwani M. Evaluation of the effect of newer antioxidant lycopene in the treatment of oral submucous fibrosis. Indian J Dent Res 2012;23:524-8.
- [28] Aung WP. The use of lycopene in oral potentially malignant disorders. Myn Dent J 2013;20:70-4.
- [29] Selvam NP, Dayanand AA. Lycopene in the management of oral submucous fibrosis. Asian J Pharm Clin Res 2013;6:58-61.
- [30] Patel JS, Umarji HR, Dhokar AA, Sapkal RB, Patel SG, Panda AK. Randomized controlled trial to evaluate theefficacy of oral lycopene in combination with vitamin E and seleniumin the treatment of oral leukoplakia. J Indian Acad Oral Med Radiol 2014;26:369-73.
- [31] Patil S, Sghaireen MG, Maheshwari S, Kunsi SR, Sahu R. Comparative study of the efficacy of lycopene and aloe verain the treatment of oral submucous fibrosis. Int J Health Allied Sci 2015;4:13-7.
- [32] Belludi SA, Verma S, Banthia R, Bhusari P, Parwani S, Kedia S, Saiprasad SV. Effect of lycopene in the treatment of periodontal disease: a clinical study. J Contemp Dent Pract. 2013;14:1054-9.
- [33] Michael McClain R, Bausch J. Summary of safety studies conducted with synthetic lycopene. Regul Toxicol Pharmacol 2003;37:274-85.
- [34] Shah PH, Venkatesh R. Lycopene: role in oral potentially malignant disorders. SMU Med J 2016;3:255-63.
Role of lycopene in the prevention of oral precancerous lesions. A review
Year 2017,
Volume: 3 Issue: 2, 101 - 105, 04.07.2017
Shishir Ram Shetty
,
Sura Ali Ahmed Fuoad Al-bayati
Mohammed Said Hamed
Hossam Abdelatty Eid Abdemagyd
Abstract
Objective. To systematically review the
methodology and results of clinical trials conducted on oral precancer patients
using lycopene. Methods. An internet search using google search engine including key words
-''lycopene, oral submucous fibrosis oral leukoplakia and oral cancer''- was
done Full text articles in English language of all the clinical trials
that were published in journals from the year 2004 to 2016 were obtained and
evaluated. Results. The data
available from the clinical trials were analyzed and presented under broad
headings of sample size, duration of study, dosage and results and presented in
tabular form. Conclusions. Lycopene
is a promising candidate in reducing cancer and oral diseases in human beings. This
review discusses the benefits of lycopene in prevention of different oral
diseases.
References
- [1] Bhardwaj R, Chaudhary K, Kaur S, Gupta R, Kamal R, Kumar M. Lycopene in oral health. Indian J Oral Sci 2013;4:125-9.
- [2] Anand D. The response of oral submucous fibrosis to lycopene - A carotenoid antioxidant: A clinicopathological study. J Clin Diagn Res 2011;5:882-8.
- [3] Danaraddi S, Koneru A, Hunasgi S, Ramalu S, Vanishree M. Natural ways to prevent and treat oral cancer. J Oral Res Rev 2014;6:34-9.
- [4] Armstron GA, Hearst JE. Carotenoids 2: Genetics and molecular biology of carotenoid pigment biosynthesis. Faseb J 1996;10:228-37.
- [5] Singh BG, Prasanth P. Lycopene- secondary suppreser for cancer. Int J Res Pharm Chem 2012;2:984-95.
- [6] Bohm F, Tinkler JH, Truscott TG. Carotenoids protect against cellmembrane damage by the nitrogen dioxide radical. Nat Med 1995;1:98-9.
- [7] Palozza P, Catalano A, Simone R, Cittadini A. Lycopene as a guardian of redox signalling. Acta Biochim Pol 2012;59:21-5.
- [8] Stahl W, Junghans A, De Boer B, Driomina ES, Briviba K, Sies H. Carotenoid mixtures protect multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein. FEBS Lett 1998;427:305-8.
- [9] Smedman AEM, Smith C. Lycopene protects DNA damage in colon cells induced by MNNG and H2O2. Anticancer Res Abs 1995;82:1656-60.
- [10] Bertram JS, Pung A, Churrby M. Review of carotenoids inhibiting malignant transformation by MCA or X-ray radiation. Carcinogenesis 1991;12:671-8.
- [11] Heber D, Lu QY. Overview of mechanisms of action of lycopene. Exp Biol Med 2002;227:920-3.
- [12] Singh M, Krishanappa R, Bagewadi A, Keluskar V. Efficacy of oral lycopene in the treatment of oral leukoplakia. Oral Oncol 2004;40:591-6.
- [13] Livny O, Kaplan I, Reifen R, Polak-Charcon S, Madar Z, Schwartz B. Lycopene inhibits proliferation and enhances gap-junction communication of KB-1 human oral tumor cells. J Nutr 2002;132:3754-9.
- [14] Gowda BB, Yathish TR , Sankappa SP, Naik KH, Somayaji P, Anand D. The response of oral submucous fibrosis to lycopene – A carotenoid antioxidant: A clinicopathological study. J Clin Diag Res 2011;5:882-8.
- [15] Palozza P, Simone RE, Catalano A, Mele MC. Tomato lycopene and lung cancer prevention: From experimental to human studies. Cancers (Basel) 2011;3:2333-57.
- [16] Liu C, Russell RM, Wang XD. Lycopene supplementation prevents smoke-induced changes in p53, p53 phosphorylation, cell proliferation, and apoptosis in the gastric mucosa of ferrets. J Nutr 2006;136:106-11.
- [17] Shetti N, Patil R. Antioxidants: its beneficial role against health damaging free radical. World J SciTechnol 2011;1:46-51.
- [18] Reddy ES. Role of antioxidants in precancerous lesions. J Ind Den Assc 2011;3:99-101.
- [19] Gowda BB, Yathish TR, Sinhasan SP, Kumar NH, Purushotham S, Anand D. The response of oral submucous fibrosis to lycopene-A carotenoid antioxidant: A clinicopathological study. J Clin Diagn Res 2011;5:882-8.
- [20] Schierle J, Bretzel, W, Buhler I, Faccin N, Hess D, Steiner K, et al. Content and isomeric ratio of lycopene in food and human blood plasma. Food Chem 1997;59:459-65.
- [21] Halloway DE, Yang M, Paganga G, Rice-Evans CA, BramleyPM. Isomerization of dietary lycopene during assimilation and transport in plasma. Free Radical Res 2000;32:93-102.
- [22] Re R, Fraser PD, Long M, Bramley PM, Rice-Evans C. Isomerization of lycopene in the gastric milieu. Biochem Biophys Res Commun 2001;281:576-81.
- [23] Boileau TWM, Boileau AC, Erdman JW. Bioavailability of all trans and cis-isomers of lycopene. Exp Biol Med 2002;227:914-9.
- [24] Richelle M, Bortlik K, Liardet S, Hager, C, Lambelet P, Baur M, et al. A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste. J Nutr 2002;132:404-8.
- [25] Agarwal S, Rao AV. Tomatolycopene and low-density lipoproteinoxidation: a human dietary intervention study. Lipids 1998;33: 981-4.
- [26] Kumar A, Bagewadi A, Keluskar V, Singh M. Efficacy of lycopene in the management of oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:207-13.
- [27] Karemore TV, Motwani M. Evaluation of the effect of newer antioxidant lycopene in the treatment of oral submucous fibrosis. Indian J Dent Res 2012;23:524-8.
- [28] Aung WP. The use of lycopene in oral potentially malignant disorders. Myn Dent J 2013;20:70-4.
- [29] Selvam NP, Dayanand AA. Lycopene in the management of oral submucous fibrosis. Asian J Pharm Clin Res 2013;6:58-61.
- [30] Patel JS, Umarji HR, Dhokar AA, Sapkal RB, Patel SG, Panda AK. Randomized controlled trial to evaluate theefficacy of oral lycopene in combination with vitamin E and seleniumin the treatment of oral leukoplakia. J Indian Acad Oral Med Radiol 2014;26:369-73.
- [31] Patil S, Sghaireen MG, Maheshwari S, Kunsi SR, Sahu R. Comparative study of the efficacy of lycopene and aloe verain the treatment of oral submucous fibrosis. Int J Health Allied Sci 2015;4:13-7.
- [32] Belludi SA, Verma S, Banthia R, Bhusari P, Parwani S, Kedia S, Saiprasad SV. Effect of lycopene in the treatment of periodontal disease: a clinical study. J Contemp Dent Pract. 2013;14:1054-9.
- [33] Michael McClain R, Bausch J. Summary of safety studies conducted with synthetic lycopene. Regul Toxicol Pharmacol 2003;37:274-85.
- [34] Shah PH, Venkatesh R. Lycopene: role in oral potentially malignant disorders. SMU Med J 2016;3:255-63.