Research Article
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Year 2017, Volume: 3 Issue: 3, 227 - 233, 04.11.2017
https://doi.org/10.18621/eurj.345667

Abstract

References

  • [1] Roberts W. Cardiac neoplasms. In: Topol E, ed. Textbook of Cardiovascular Medicine. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2002:917-22.
  • [2] Yavuz S, Toktas F, Eris C, Ata Y, Turk T, Goncu T. Left atrial mass in a patient with previous coronary artery bypass grafting. Journal-CVS 2014;2:7-9.
  • [3] Hill M, Cherry C, Maloney M, Midyette P. Surgical resection of atrial myxomas. AORN J 2010;92:393-406.
  • [4] Yavuz S, Toktas F, Eris C, Ata Y, Turk T, Goncu T. Recurrent multiple cardiac myxomas. Brastisl Lek Listy 2010;111:549-51.
  • [5] Aggarwal SK, Barik R, Sarma TCSR, Iyer VR, Sai V, Mishra J, et al. Clinical presentation and investigation findings in cardiac myxomas: new insight from the developing world. Am Heart J 2007;154:1102-7.
  • [6] Meşe B, Arıkan A, Karabörk O, Özsin KK. [Using the superior septal approach to excise a giant left atrial myxoma: A case report]. Turk Gogus Kalp Dama 2012;20:596-9. [Article in Turkish]
  • [7] Kaplan M, Demirtas MM, Cimen S, Gercekoglu H, Yapici F, Ozler A. [Cardiac myxomas: surgical experience with 45 cases]. Turk Gogus Kalp Dama 2002;10:11-4. [Article in Turkish]
  • [8] Taş S, Tunçer E, Boyacıoğlu K, Antal Dönmez A, Bengi Bakal R, Kayalar N, et al. Cardiac myxomas: a 27-year surgical experience. Turk Gogus Kalp Dama 2014;22:526-33.
  • [9] Swartz MF, Lutz CJ, Chandan VS, Landas S, Fink GW. Atrial myxomas: pathologic types, tumor location, and presenting symptoms. J Card Surg 2006;21:435-40.
  • [10] Garatti A, Nano G, Canziani A, Gagliardotto P, Mossuto E, Frigiola A, et al. Surgical excision of cardiac myxomas: twenty years experience at a single institution. Ann Thorac Surg 2012;93:825-31.
  • [11] Ha JW, Kang WC, Chung N, Chang BC, Rim SJ, Kwon JW, et al. Echocardiographic and morphologic characteristics of left atrial myxoma and their relation to systemic embolism. Am J Cardiol 1999;83:1579-82.
  • [12] Kimura K, Iezumi Y, Noma S, Fukuda K. Left to right protrusion of a left atrial myxoma through a patent foramen ovale in a patient with ‘cryptogenic’ pulmonary embolism. Eur Heart J 2010;31:1247.
  • [13] He DK, Zhang YF, Liang Y, Ye SX, Wang C, Kang B, et al. Risk factors for embolism in cardiac myxoma: a retrospective analysis. Med Sci Monit 2015;21:1146-54.
  • [14] Garatti A, Nano G, Canziani A, Gagliardotto P, Mossuto E, Frigiola A, et al. Surgical excision of cardiac myxomas: twenty years experience at a single institution. Ann Thorac Surg 2012;93:825-31.
  • [15] Shahbaaz MK, Sanki PK, Hossain MZ, Charles A, Bhattacharya S, Sarkar UN. Cardiac myxoma: a surgical experience of 38 patients over 9 years, at SSKM hospital Kolkata, India. South Asian J Cancer 2013;2:83-6.
  • [16] McCarthy PM, Schaff HV, Winkler HZ, Lieber MM, Carney JA. Deoxyribonucleic acid ploidy pattern of cardiac myxomas. Another predictor of biologically unusual myxomas. J Thorac Cardiovasc Surg 1989;98:1083-6.
  • [17] Yavuz S, Celkan A, Ata Y, Mavi M, Turk T, Eris C, et al. Mitral valve myxoma. Asian Cardiovasc Thorac Ann 2000;8:64-6.
  • [18] Gucu A, Demir D, Kahraman N, Engin M, Ozyazicioglu AF, Goncu MT. Mitral valve myxoma associated with intracranial tumor: a case report. Eur Res J 2016;2:233-5.
  • [19] Erdil N, Ates S, Cetin L, Demirkilic U, Sener E, Tatar H. Frequency of left atrial myxoma with concomitant coronary artery disease. Surg Today 2003;33:328-31.
  • [20] Ito S, Endo A, Okada T, Nakamura T, Adachi T, Nakashima R, et al. Acute myocardial infarction due to left atrial myxoma. Intern Med 2016;55:49-54.

Cardiac myxomas: an analysis of 39 patients

Year 2017, Volume: 3 Issue: 3, 227 - 233, 04.11.2017
https://doi.org/10.18621/eurj.345667

Abstract

Objectives. Myxomas
are the most common benign primary heart tumors. They have serious
complications including intracardiac blood flow obstruction and embolic events.
The aim of the study was to assess our experiences related to patients
undergoing surgical resection for cardiac myxomas. Methods. The medical
records of 39 patients, aged 16 to 76 years (mean, 47.5 years), who were
operated on for primary cardiac myxomas between January 1994 and December 2016
at our clinic were retrospectively evaluated.
Demographic, clinical, operative and postoperative data were obtained
from these hospital medical records.
Cardiac myxomas were
diagnosed by transthoracic echocardiography. Preoperative coronary angiography
was performed in patients over 40 years of age and those with symptoms of
coronary disease. In routine follow-up after discharge the patients were
checked by echocardiography. Long-term cumulative survival was analyzed using
the Kaplan-Meier method. Results.
There was no in-hospital mortality. The
majority (61.5%) of patients were female. The most common encountered
localization of myxoma was the left atrium (76.9%), and the classic posterior
approach from interatrial groove was preferred in 32 (82.1%) patients. Mean
follow-up was 6.05 ± 3.75 years (range, 1-10 years). Five (12.8%) patients were
lost on long-term follow-up. Kaplan-Meier curves, cumulative proportion
surviving of patients at 1-, 2-, 5-, and 10-year were 97.4%, 91.7%, 84.7%, and
84.7%, respectively. No hospital mortality was observed in any of the patients.
There was no recurrence in our series. Conclusions.
Myxoma is the disease that can lead to complications such as embolic events
and intracardiac blood flow obstruction. It can be excised with a low rate of
morbidity and mortality. S
urgical
resection should be performed promptly after diagnosis in order to prevent
potential complications. 

References

  • [1] Roberts W. Cardiac neoplasms. In: Topol E, ed. Textbook of Cardiovascular Medicine. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2002:917-22.
  • [2] Yavuz S, Toktas F, Eris C, Ata Y, Turk T, Goncu T. Left atrial mass in a patient with previous coronary artery bypass grafting. Journal-CVS 2014;2:7-9.
  • [3] Hill M, Cherry C, Maloney M, Midyette P. Surgical resection of atrial myxomas. AORN J 2010;92:393-406.
  • [4] Yavuz S, Toktas F, Eris C, Ata Y, Turk T, Goncu T. Recurrent multiple cardiac myxomas. Brastisl Lek Listy 2010;111:549-51.
  • [5] Aggarwal SK, Barik R, Sarma TCSR, Iyer VR, Sai V, Mishra J, et al. Clinical presentation and investigation findings in cardiac myxomas: new insight from the developing world. Am Heart J 2007;154:1102-7.
  • [6] Meşe B, Arıkan A, Karabörk O, Özsin KK. [Using the superior septal approach to excise a giant left atrial myxoma: A case report]. Turk Gogus Kalp Dama 2012;20:596-9. [Article in Turkish]
  • [7] Kaplan M, Demirtas MM, Cimen S, Gercekoglu H, Yapici F, Ozler A. [Cardiac myxomas: surgical experience with 45 cases]. Turk Gogus Kalp Dama 2002;10:11-4. [Article in Turkish]
  • [8] Taş S, Tunçer E, Boyacıoğlu K, Antal Dönmez A, Bengi Bakal R, Kayalar N, et al. Cardiac myxomas: a 27-year surgical experience. Turk Gogus Kalp Dama 2014;22:526-33.
  • [9] Swartz MF, Lutz CJ, Chandan VS, Landas S, Fink GW. Atrial myxomas: pathologic types, tumor location, and presenting symptoms. J Card Surg 2006;21:435-40.
  • [10] Garatti A, Nano G, Canziani A, Gagliardotto P, Mossuto E, Frigiola A, et al. Surgical excision of cardiac myxomas: twenty years experience at a single institution. Ann Thorac Surg 2012;93:825-31.
  • [11] Ha JW, Kang WC, Chung N, Chang BC, Rim SJ, Kwon JW, et al. Echocardiographic and morphologic characteristics of left atrial myxoma and their relation to systemic embolism. Am J Cardiol 1999;83:1579-82.
  • [12] Kimura K, Iezumi Y, Noma S, Fukuda K. Left to right protrusion of a left atrial myxoma through a patent foramen ovale in a patient with ‘cryptogenic’ pulmonary embolism. Eur Heart J 2010;31:1247.
  • [13] He DK, Zhang YF, Liang Y, Ye SX, Wang C, Kang B, et al. Risk factors for embolism in cardiac myxoma: a retrospective analysis. Med Sci Monit 2015;21:1146-54.
  • [14] Garatti A, Nano G, Canziani A, Gagliardotto P, Mossuto E, Frigiola A, et al. Surgical excision of cardiac myxomas: twenty years experience at a single institution. Ann Thorac Surg 2012;93:825-31.
  • [15] Shahbaaz MK, Sanki PK, Hossain MZ, Charles A, Bhattacharya S, Sarkar UN. Cardiac myxoma: a surgical experience of 38 patients over 9 years, at SSKM hospital Kolkata, India. South Asian J Cancer 2013;2:83-6.
  • [16] McCarthy PM, Schaff HV, Winkler HZ, Lieber MM, Carney JA. Deoxyribonucleic acid ploidy pattern of cardiac myxomas. Another predictor of biologically unusual myxomas. J Thorac Cardiovasc Surg 1989;98:1083-6.
  • [17] Yavuz S, Celkan A, Ata Y, Mavi M, Turk T, Eris C, et al. Mitral valve myxoma. Asian Cardiovasc Thorac Ann 2000;8:64-6.
  • [18] Gucu A, Demir D, Kahraman N, Engin M, Ozyazicioglu AF, Goncu MT. Mitral valve myxoma associated with intracranial tumor: a case report. Eur Res J 2016;2:233-5.
  • [19] Erdil N, Ates S, Cetin L, Demirkilic U, Sener E, Tatar H. Frequency of left atrial myxoma with concomitant coronary artery disease. Surg Today 2003;33:328-31.
  • [20] Ito S, Endo A, Okada T, Nakamura T, Adachi T, Nakashima R, et al. Acute myocardial infarction due to left atrial myxoma. Intern Med 2016;55:49-54.
There are 20 citations in total.

Details

Subjects Health Care Administration
Journal Section Original Articles
Authors

Faruk Toktaş 0000-0002-0820-3879

Şenol Yavuz 0000-0001-5246-0808

Kadir Kaan Özsin 0000-0001-5933-9322

Umut Serhat Sanrı 0000-0003-4008-4336

Tamer Türk

Mehmet Tuğrul Göncü 0000-0002-3666-8673

Publication Date November 4, 2017
Submission Date October 22, 2017
Acceptance Date October 26, 2017
Published in Issue Year 2017 Volume: 3 Issue: 3

Cite

AMA Toktaş F, Yavuz Ş, Özsin KK, Sanrı US, Türk T, Göncü MT. Cardiac myxomas: an analysis of 39 patients. Eur Res J. November 2017;3(3):227-233. doi:10.18621/eurj.345667

e-ISSN: 2149-3189 


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