Wrongs known as right in thyroid scintigraphy and uptake study

Year 2019, Volume: 5 Issue: 1, 142 - 147, 04.01.2019

Serdar Savaş Gül

https://doi.org/10.18621/eurj.410060

Cited By: 1

Abstract

Objectives:
Thyroid scintigraphy using ^99mTc-pertechnetate is commonly used to study function and
structure of thyroid gland. Pin-hole
collimator is generally preferred in thyroid scintigraphy and uptake
studies. The purpose
of the present study was to determine
actual radiopharmaceutical uptake value in an
experimental ^99mTc-pertechnetate thyroid scintigraphy and uptake
model.

Methods: Thyroid hyperactive and hypoactive nodule models were created using 4 mCi (148 MBq) ^99mTc-pertechnetate.
In
the experimental model, 4 mm, 6 mm and 8 mm
diameter pin-hole collimators, and 5 cm, 7 cm and 10 cm object-to-pinhole
distances were investigated.

Results: In thyroid
hyperactive nodule model, despite the same activity value, uptake at 7 cm object-to-pinhole distance was higher compared to 10 cm distance (122%
and 103%, respectively). In the patient with Graves’ disease, despite the same
activity value, uptake at 5 cm object-to-pinhole distance was higher compared
to 10 cm distance (8% and 4%, respectively). In thyroid hypoactive nodule
model, 4 mm, 6 mm and 8 mm diameters pin-hole collimators were imaged at 5 cm,
10 cm and 15 cm object-to-pinhole distances. The resolution differences between the images were
evaluated.

Conclusion: It
was determined that imaging using 10 cm object-to-pinhole
distanceand 4 mm
diameter pin-hole collimator was best in terms of image resolution and optimum ^99mTc-pertechnetate
uptake level. 

Keywords

99mTc-pertechnetate, thyroid, scintigraphy, uptake

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