Research Article
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Year 2019, Volume: 5 Issue: 3, 540 - 544, 04.05.2019
https://doi.org/10.18621/eurj.376503

Abstract

References

  • [1] Cots JM, Alos JI, Barcena M, Boleda X, Canada JL, Gomez N, et al. Recommendations for management of acute pharyngitis in adults. Acta Otorrinolaringol Esp 2015;66:159-70.
  • [2] Kim S. Optimal diagnosis and treatment of group A streptococcal pharyngitis. Infect Chemother 2015;47:202-4.
  • [3] Agarwal M, Raghuwanshi SK, Asati DP. Antibiotic use in sore throat: are we judicious? Indian J Otolaryngol Head Neck Surg 2015;67:267-70.
  • [4] Bisno AL, Gerber MA, Gwaltney JM Jr, Kaplan EL, Schwartz RH. Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Clin Infect Dis 2002;35:113-25.
  • [5] Ayranci U, Akgun Y, Unluoglu I, Kiremitci A. Antibiotic prescribing patterns for sore throat infections in a University-based primary care clinic. Ann Saudi Med 2005;25:22-8.
  • [6] Linder JA, Stafford RS. Antibiotic treatment of adults with sore throat by community primary care physicians: a national survey, 1989-1999. JAMA 2001;286:1181-6.
  • [7] Ebell MH, Smith MA, Barry HC, Ives K, Carey M. Does this patient have strep throat? JAMA 2000;284:2912-8.
  • [8] Regoli M, Chiappini E, Bonsignori F, Galli L, de Martino M. Update on the management of acute pharyngitis in children. Ital J Pediatr 2011;37:10.
  • [9] Aalbers J, O'Brien KK, Chan WS, Falk GA, Teljeur C, Dimitrov BD, et al. Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score. BMC Med 2011;9:67.
  • [10] McIsaac WJ, Goel V, To T, Low DE. The validity of a sore throat score in family practice. CMAJ 2000;163:811-5.
  • [11] Mistik S, Gokahmetoglu S, Balci E, Onuk FA. Sore throat in primary care project: a clinical score to diagnose viral sore throat. Fam Pract 2015;32:263-8.
  • [12] Maltezou HC, Tsagris V, Antoniadou A, Galani L, Douros C, Katsarolis I, et al. Evaluation of a rapid antigen detection test in the diagnosis of streptococcal pharyngitis in children and its impact on antibiotic prescription. J Antimicrob Chemother 2008;62:1407-12.
  • [13] Cooper RJ, Hoffman JR, Bartlett JG, Besser RE, Gonzales R, Hickner JM, et al. Principles of appropriate antibiotic use for acute pharyngitis in adults: background. Ann Emerg Med 2001;37:711-9.
  • [14] Snow V, Mottur-Pilson C, Cooper RJ, Hoffman JR. Principles of appropriate antibiotic use for acutepharyngitis in adults. Ann Intern Med 2001;134:506-8.
  • [15] Shulman ST, Bisno AL, Clegg HW, Gerber MA, Kaplan EL, Lee G, et al. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis 2012;55:e86-102.
  • [16] Palla AH, Khan RA, Gilani AH, Marra F. Over prescription of antibiotics for adult pharyngitis is prevalent in developing countries but can be reduced using McIsaac modification of Centor scores: a cross-sectional study. BMC Pulm Med 2012;12:70.
  • [17] Nitsch-Osuch A, Gyrczuk E, Wardyn A, Zycinska K, Brydak L. Antibiotic prescription practices among children with influenza. Adv Exp Med Biol 2016;20:25-31.
  • [18] Derhem B, Ungan M. General practitioners’ level of knowledge about their rights andcriminal liabilities according to legislation in Turkey. Fam Med Prim Care Rev 2017;19:357-60.
  • [19] McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE. Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA 2004;291:1587-95.

Antibiotic prescription before and after rapid antigen detection test (RADT) for beta-hemolytic streptococci

Year 2019, Volume: 5 Issue: 3, 540 - 544, 04.05.2019
https://doi.org/10.18621/eurj.376503

Abstract

Objectives:
Acute
pharyngo-tonsillitis is one of the diseases that pediatricians and general practitioners
most frequently experienced and only a small percentage of patients (20%-30% of
pediatric patients, even less in adults) are actually suffering from
pharyngo-tonsillitis by group A beta-hemolytic Streptococcus (GABHS). Also three quarters of pharyngitis patients
have been treated with inappropriate antibiotics even these patients have viral
infections. The aim of this study was to assess the effectiveness of the rapid
antigen detection test (RADT) on the percentage of antibiotic prescriptions
amongst patients with sore throat at a primary health care center in rural
area.

Methods: Retrospective
Cohort Study was designed to compare antibiotic prescription in patients with
sore throats in two groups, one with the use of RADT and other with the clinical desicions
of physicians. The x2 test was used between two nominal variables to
assess the impact of RADT on antibiotic prescription. For comparison of more
than two independent variables, the ANOVA test was used and to identify the
differences between groups, the Post-Hoc test was processed.

Results: Of the 580 patients, the
avarage age of the study population was 25.8 years old while the median age was
21 years (min.=3, max.=65). There was a significant difference between two
groups who had tested with RADT or not in terms of antibiotic prescription (p < 0.001). There was a significant
difference between 3-14 years of age and 15-44 years of age (p = 0.001) as well as 3-14 years of age
and 45-65 years of age (p = 0.009),
however there was no significant difference between 15-44 and 45-65 years of
age (p = 1.00).

Conclusions: Using the RADT is truly
effective in reducing the percentage of antibiotic prescriptions in our
setting. We believe that, the tools like RADTs which are quickly results and
easy to use are really useful in practising (particularly in rural area).

References

  • [1] Cots JM, Alos JI, Barcena M, Boleda X, Canada JL, Gomez N, et al. Recommendations for management of acute pharyngitis in adults. Acta Otorrinolaringol Esp 2015;66:159-70.
  • [2] Kim S. Optimal diagnosis and treatment of group A streptococcal pharyngitis. Infect Chemother 2015;47:202-4.
  • [3] Agarwal M, Raghuwanshi SK, Asati DP. Antibiotic use in sore throat: are we judicious? Indian J Otolaryngol Head Neck Surg 2015;67:267-70.
  • [4] Bisno AL, Gerber MA, Gwaltney JM Jr, Kaplan EL, Schwartz RH. Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Clin Infect Dis 2002;35:113-25.
  • [5] Ayranci U, Akgun Y, Unluoglu I, Kiremitci A. Antibiotic prescribing patterns for sore throat infections in a University-based primary care clinic. Ann Saudi Med 2005;25:22-8.
  • [6] Linder JA, Stafford RS. Antibiotic treatment of adults with sore throat by community primary care physicians: a national survey, 1989-1999. JAMA 2001;286:1181-6.
  • [7] Ebell MH, Smith MA, Barry HC, Ives K, Carey M. Does this patient have strep throat? JAMA 2000;284:2912-8.
  • [8] Regoli M, Chiappini E, Bonsignori F, Galli L, de Martino M. Update on the management of acute pharyngitis in children. Ital J Pediatr 2011;37:10.
  • [9] Aalbers J, O'Brien KK, Chan WS, Falk GA, Teljeur C, Dimitrov BD, et al. Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score. BMC Med 2011;9:67.
  • [10] McIsaac WJ, Goel V, To T, Low DE. The validity of a sore throat score in family practice. CMAJ 2000;163:811-5.
  • [11] Mistik S, Gokahmetoglu S, Balci E, Onuk FA. Sore throat in primary care project: a clinical score to diagnose viral sore throat. Fam Pract 2015;32:263-8.
  • [12] Maltezou HC, Tsagris V, Antoniadou A, Galani L, Douros C, Katsarolis I, et al. Evaluation of a rapid antigen detection test in the diagnosis of streptococcal pharyngitis in children and its impact on antibiotic prescription. J Antimicrob Chemother 2008;62:1407-12.
  • [13] Cooper RJ, Hoffman JR, Bartlett JG, Besser RE, Gonzales R, Hickner JM, et al. Principles of appropriate antibiotic use for acute pharyngitis in adults: background. Ann Emerg Med 2001;37:711-9.
  • [14] Snow V, Mottur-Pilson C, Cooper RJ, Hoffman JR. Principles of appropriate antibiotic use for acutepharyngitis in adults. Ann Intern Med 2001;134:506-8.
  • [15] Shulman ST, Bisno AL, Clegg HW, Gerber MA, Kaplan EL, Lee G, et al. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis 2012;55:e86-102.
  • [16] Palla AH, Khan RA, Gilani AH, Marra F. Over prescription of antibiotics for adult pharyngitis is prevalent in developing countries but can be reduced using McIsaac modification of Centor scores: a cross-sectional study. BMC Pulm Med 2012;12:70.
  • [17] Nitsch-Osuch A, Gyrczuk E, Wardyn A, Zycinska K, Brydak L. Antibiotic prescription practices among children with influenza. Adv Exp Med Biol 2016;20:25-31.
  • [18] Derhem B, Ungan M. General practitioners’ level of knowledge about their rights andcriminal liabilities according to legislation in Turkey. Fam Med Prim Care Rev 2017;19:357-60.
  • [19] McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE. Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA 2004;291:1587-95.
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Articles
Authors

Baki Derhem 0000-0002-6989-9873

Süleyman Özsarı 0000-0002-7160-3381

Selman Erturhan This is me 0000-0001-5040-2639

Publication Date May 4, 2019
Submission Date January 9, 2018
Acceptance Date April 18, 2018
Published in Issue Year 2019 Volume: 5 Issue: 3

Cite

AMA Derhem B, Özsarı S, Erturhan S. Antibiotic prescription before and after rapid antigen detection test (RADT) for beta-hemolytic streptococci. Eur Res J. May 2019;5(3):540-544. doi:10.18621/eurj.376503

e-ISSN: 2149-3189 


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