Is there a difference in 25-hydroxyvitamin D levels between female university students with and without joint hypermobility?

Year 2019, Volume: 5 Issue: 4, 576 - 581, 04.07.2019

Filiz Tuna Hande Özdemir Derya Demirbağ Kabayel Zeynep Banu Doğanlar

https://doi.org/10.18621/eurj.411056

Cited By: 1

Abstract

Objectives:
Individuals with joint hypermobility (JH) constitute a sensitive group with
regard to musculoskeletal problems. This study aimed to investigate whether
females with generalized joint hypermobility (GJH) are at risk of
hypovitaminosis D compared with non-GJH female participants and whether there
is a relationship between vitamin D levels, Beighton score and musculoskeletal
complaints.

Methods: In this
cross-sectional, descriptive and case-control study, 76 female participants aged
18-25 years were included. The Beighton score with a cut-off of 4/9 was applied
for defining GJH. In addition, serum biochemical (the enzymatic colorimetric
method) and hormonal (the electrochemiluminescence method) parameters were
evaluated.

Results: The mean
serum 25-hydroxyvitamin D (25[OH]D) levels of GJH (n = 38) and non-GJH (n = 38)
groups were 15.70 ± 7.96 ng/mL and 16.80 ± 5.45 ng/mL, respectively. There was
no statistically significant difference between the groups in terms of
biochemical and hormonal parameters. We found vitamin D deficiency in 89.5% of
participants with GJH, and 84.2% of controls. There was no correlation between
vitamin D, Brighton criteria, and musculoskeletal complaints.

Conclusion: The
female participants with GJH showed similar frequency of musculoskeletal
complaints and similar low level of 25(OH)D in relation to controls. 

Keywords

female, joint hypermobility, musculoskeletal complaints, 25-hydroxyvitamin D deficiency

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