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The relationship of simplified acute physiology score 3 (SAPS 3) and C-reactive protein (CRP) levels with mortality rates and length of stay of patients in surgical intensive care unit

Year 2019, Volume: 5 Issue: 5, 751 - 756, 04.09.2019
https://doi.org/10.18621/eurj.422079

Abstract

Objectives: The individual risk of surgical patients is more often
underestimated and < 15% of patients who underwent surgery were admitted to
ICU. The prognostic scores were developed to assess the mortality rate and
prognosis for critical patients including surgical ones. T
he
Acute Physiology and Chronic Health Evaluation (APACHE) score and the Simplified
Acute Physiology Score (SAPS)
were most popular ones and they were revised with the improvements
in health care opportunities. As a prognostic scoring system SAPS 3’ results
were defined as excellent in high risk surgical patient study group. CRP is
useful as a prognostic indicator or an index of disease progression but its
value has not been tested in acute settings adequately. The aim of this study
is to test the calibration power of SAPS 3 score and identify correlations
between hospital mortality and patient outcomes with SAPS 3 scores and CRP
levels.

Methods: This retrospective and
analytical study was conducted one year period in surgical ICUs of tertiary
level of attention in a public institution.
It was a case–control medical record review and the
patients included in this study were those who admitted in the surgical ICU for
any reason.

Results: A total of 806 patients admitted to the
Gastroenterological surgical ICU was included in the study between March 2016
and March 2017. The relation between mortality rate, length of stay in ICU and
SAPS 3 score was significant statistically and the relation of CRP levels with
SAPS score and mortality rate was found significant statistically.







Conclusion: The discriminative power of SAPS 3 score was very good
and the calibration was appropriate. 

References

  • [1] Caldeira VM, Silva Júnior JM, Oliveira AM, Rezende S, Araújo LA, Santana MR, et al. Criteria for patient admission to an intensive care unit and related mortality rates. Rev Assoc Med Bras (1992) 2010;56:528-34.
  • [2] Jhanji S, Thomas B, Ely A, Watson D, Hinds CJ, Pearse RM. Mortality and utilisation of critical care resources amongst high-risk surgical patients in a large NHS trust. Anaesthesia 2008;63:695-700.
  • [3] Bennett-Guerrero E, Hyam JA, Shaefi S, Prytherch DR, Sutton GL, Weaver PC, et al. Comparison of P-POSSUM risk adjusted mortality rates after surgery between patients in the USA and the UK. Br J Surg 2003;90:1593-8.
  • [4] Silva JM Jr, Rocha HMC, Katayama HT, Dias LF, de Paula MB, Andraus LMR, et al. SAPS 3 score as a predictive factor for postoperative referral to intensive care unit. Ann Intensive Care 2016;6:42.
  • [5] Sakr Y, Krauss C, Amaral A, Réa-Neto A, Specht M, Reinhart K, et al. Comparison of the performance of SAPS II, SAPS 3, APACHE II, and their customized prognostic models in a surgical intensive care unit. Br J Anaesth 2008;101:798-803.
  • [6] Moreno RP, Metnitz PG, Almeida E, Jordan B, Bauer P, Campos RA, et al. SAPS 3--from evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission. Intensive Care Med 2005;31:1345-55.
  • [7] Silva Junior JM, Malbouisson LM, Nuevo HL, Barbosa LG, Marubayashi LY, Teixeira IC, et al. Applicability of the simplified acute physiology score (SAPS 3) in Brazilian hospitals. Rev Bras Anestesiol 2010;60:20-31.
  • [8] Evran T, Serin S, Gürses E, Sungurtekin H. Various scoring systems for predicting mortality in Intensive Care Unit. Niger J Clin Pract 2016;19:530-4.
  • [9] Ledoux D1, Canivet JL, Preiser JC, Lefrancq J, Damas P. SAPS 3 admission score: an external validation in a general intensive care population. Intensive Care Med 2008;34:1873-7.
  • [10] Chandrashekara S. C-reactive protein: an inflammatory marker with specific role in physiology, pathology, and diagnosis. IJRCI 2014;2(S1):SR3.
  • [11] Kaur M. C-reactive protein. A prognostic indicator. IJABMR 2017;7:83-4.
  • [12] Strand K, Flaatten H. Severity scoring in the ICU: a review. Acta Anaesthesiol Scand 2008;52:467-78.
  • [13] Kuzniewicz MW, Vasilevskis EE, Lane R, Dean ML, Trivedi NG, Rennie DJ, et al. Variation in ICU risk-adjusted mortality: impact of methods of assessment and potential confounders. Chest 2008;133:1319-27.
  • [14] Nassar APJ, Malbouisson LM, Moreno R. Evaluation of Simplified Acute Physiology Score 3 performance: a systematic review of external validation studies. Crit Care 2014;18:R117.
  • [15] Pieri G, Agarwal B, Burroughs AK. C-reactive protein and bacterial infection in cirrhosis. Ann Gastroenterol 2014;27:113-20.
Year 2019, Volume: 5 Issue: 5, 751 - 756, 04.09.2019
https://doi.org/10.18621/eurj.422079

Abstract

References

  • [1] Caldeira VM, Silva Júnior JM, Oliveira AM, Rezende S, Araújo LA, Santana MR, et al. Criteria for patient admission to an intensive care unit and related mortality rates. Rev Assoc Med Bras (1992) 2010;56:528-34.
  • [2] Jhanji S, Thomas B, Ely A, Watson D, Hinds CJ, Pearse RM. Mortality and utilisation of critical care resources amongst high-risk surgical patients in a large NHS trust. Anaesthesia 2008;63:695-700.
  • [3] Bennett-Guerrero E, Hyam JA, Shaefi S, Prytherch DR, Sutton GL, Weaver PC, et al. Comparison of P-POSSUM risk adjusted mortality rates after surgery between patients in the USA and the UK. Br J Surg 2003;90:1593-8.
  • [4] Silva JM Jr, Rocha HMC, Katayama HT, Dias LF, de Paula MB, Andraus LMR, et al. SAPS 3 score as a predictive factor for postoperative referral to intensive care unit. Ann Intensive Care 2016;6:42.
  • [5] Sakr Y, Krauss C, Amaral A, Réa-Neto A, Specht M, Reinhart K, et al. Comparison of the performance of SAPS II, SAPS 3, APACHE II, and their customized prognostic models in a surgical intensive care unit. Br J Anaesth 2008;101:798-803.
  • [6] Moreno RP, Metnitz PG, Almeida E, Jordan B, Bauer P, Campos RA, et al. SAPS 3--from evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission. Intensive Care Med 2005;31:1345-55.
  • [7] Silva Junior JM, Malbouisson LM, Nuevo HL, Barbosa LG, Marubayashi LY, Teixeira IC, et al. Applicability of the simplified acute physiology score (SAPS 3) in Brazilian hospitals. Rev Bras Anestesiol 2010;60:20-31.
  • [8] Evran T, Serin S, Gürses E, Sungurtekin H. Various scoring systems for predicting mortality in Intensive Care Unit. Niger J Clin Pract 2016;19:530-4.
  • [9] Ledoux D1, Canivet JL, Preiser JC, Lefrancq J, Damas P. SAPS 3 admission score: an external validation in a general intensive care population. Intensive Care Med 2008;34:1873-7.
  • [10] Chandrashekara S. C-reactive protein: an inflammatory marker with specific role in physiology, pathology, and diagnosis. IJRCI 2014;2(S1):SR3.
  • [11] Kaur M. C-reactive protein. A prognostic indicator. IJABMR 2017;7:83-4.
  • [12] Strand K, Flaatten H. Severity scoring in the ICU: a review. Acta Anaesthesiol Scand 2008;52:467-78.
  • [13] Kuzniewicz MW, Vasilevskis EE, Lane R, Dean ML, Trivedi NG, Rennie DJ, et al. Variation in ICU risk-adjusted mortality: impact of methods of assessment and potential confounders. Chest 2008;133:1319-27.
  • [14] Nassar APJ, Malbouisson LM, Moreno R. Evaluation of Simplified Acute Physiology Score 3 performance: a systematic review of external validation studies. Crit Care 2014;18:R117.
  • [15] Pieri G, Agarwal B, Burroughs AK. C-reactive protein and bacterial infection in cirrhosis. Ann Gastroenterol 2014;27:113-20.
There are 15 citations in total.

Details

Primary Language English
Subjects Surgery, Anaesthesiology, Gastroenterology and Hepatology, Health Care Administration
Journal Section Original Articles
Authors

İbrahim Mungan 0000-0003-0002-3643

Sema Turan 0000-0003-2443-0390

Dilek Kazancı 0000-0002-8021-1451

Hayriye Cankar Dal This is me 0000-0003-4744-9959

Serdar Yamanyar This is me 0000-0002-2360-0303

Sultan Sevim Yakın This is me 0000-0002-5782-1403

Erdal Birol Bostancı This is me 0000-0002-0663-0156

Publication Date September 4, 2019
Submission Date May 8, 2018
Acceptance Date January 14, 2019
Published in Issue Year 2019 Volume: 5 Issue: 5

Cite

AMA Mungan İ, Turan S, Kazancı D, Cankar Dal H, Yamanyar S, Sevim Yakın S, Bostancı EB. The relationship of simplified acute physiology score 3 (SAPS 3) and C-reactive protein (CRP) levels with mortality rates and length of stay of patients in surgical intensive care unit. Eur Res J. September 2019;5(5):751-756. doi:10.18621/eurj.422079

e-ISSN: 2149-3189 


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