Idiopathic granulomatous mastitis: factors influencing recovery and recurrence

Year 2019, Volume: 5 Issue: 5, 768 - 775, 04.09.2019

Hüseyin Onur Aydın , Ataç Baykal Ali Konan Volkan Kaynaroğlu

https://doi.org/10.18621/eurj.424016

Cited By: 1

Abstract

Objectives:
Idiopathic granulomatous mastitis
(IGM) is an idiopathic, inflammatory, and benign disease of the breast. The aim
of this study was to determine possible risk factors for the recurrence of IGM
in patients treated with different treatment modalities.

Methods: It
was planned to explore the risk factors of the disease through the evaluation
of the medical records of 81 patients with the relevant diagnosis in the
archives of Hacettepe University. The medical records of the patients were
retrospectively screened for information regarding age, sex, total number of pregnancies,
duration of breastfeeding, rheumatologic diseases, size and recurrence of the
radiologically detected lesions. The results of two-year follow-up of the
patients after the treatment were evaluated. The rates of recovery and
recurrence after the treatment were determined for patients who received
antibiotic therapy alone, who underwent wide excision alone, who received
antibiotic therapy in combination with steroid therapy, and who received added
azathioprine and/or methotrexate therapy.

Results: No
significant difference was observed between 12 patients having recurrence and
69 patients having no recurrence. However, the recovery time was shorter for
patients with a lesion size of ≤ 20 mm who underwent wide excision or received
antibiotic therapy alone.

Conclusion: Among
patients with a mass size ≤ 20 mm, those treated with wide excision and
antibiotic therapy alone had shorter recovery times compared with those who
received immunosuppressive therapy. In addition, it may take more than two
years to terminate the treatment in patients who received medical treatment
alone.

Keywords

idiopathic granulomatous mastitis, recovery, recurrence, treatment, breast

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