The drug adherence and lifestyle factors that contribute to blood pressure control among hypertensive patients

Year 2019, Volume: 5 Issue: 5, 853 - 860, 04.09.2019

Zeynep Güneş Özünal , İliriana Alloqi Tahirbegolli Mehmet Baykal Belen Ateş Bernard Tahirbegolli Yiğit Kılıç Selçuk Şen , Ali Yağız Üresin

https://doi.org/10.18621/eurj.431174

Cited By: 2

Abstract

Objectives: To investigate drug adherence and
lifestyle behaviors affecting the blood pressure (BP) control among
hypertensive patients that have uncontrolled and controlled BP.

Methods: Seventy-eight uncontrolled BP and 98 controlled BP
hypertensive patients matched on age, gender, time since hypertension diagnosis
and the number of antihypertensive drugs used were investigated using a
standardized questionnaire to evaluate lifestyle behaviors, drug adherence, the
use of complementary and alternative medicine, and health related quality of
life. Drug-drug interactions were evaluated with an electronic drug reference
software.

Results: Not taking therapy when feeling better was observed
significantly more frequently in the uncontrolled hypertensive group (OR:
0.297, %95 CI: 0.115-0.770). Uncontrolled BP hypertensive patients live more
frequently in extended family settings (p
= 0.043), they sleep less controlled BP hypertensive patients (OR: 0.749, %95
CI: 0.605-0.929). The groups did not differ statistically in terms of
Complementary and Alternative Medicine (CAM) use (p = 0.795) and informing doctors about the use of CAMs (p = 0.910). The EuroQol five-dimensional 3 level (EQ5D3L) questionnaire Visual Analogue Scale (VAS) score was significantly
higher in the control group (p = 0.011).
In both groups over 70% of patients should be monitored for therapy due to drug
interactions evaluation.

Conclusions:
Our study shows that increasing the drug adherence and sleeping hours and
living in the nuclear family is associated with improvement in blood pressure
control and health related quality of life. A comprehensive approach and good
patient-physician communication and trust are essential for well-managed
hypertension.

Keywords

Hypertension, drug adherence, drug interaction

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