Year 2020, Volume 6 , Issue 2, Pages 169 - 172 2020-03-04

Three cases with Klippel-Trenaunay syndrome and treatment options

Ersin ÇELİK [1] , İlker ALAT [2]

Klippel-Trenaunay syndrome (KTS) is a rare congenital anomaly characterized by capillary malformations, soft tissue and bone hypertrophy and varicosities. The presence of at least two of the three clinical conditions is sufficient for the diagnosis of KTS. Early diagnosis and treatment are important because of possible serious complications such as deep vein thrombosis and pulmonary embolism. Venous system aplasia and/or hypoplasia might be observed in KTS. Therefore, deep venous system must be evaluated definitely before determining the treatment strategy. It's herein presented our conservative and surgical treatment applications in three KTS patients. 

Klippel-Trenaunay syndrome, embryonic, varicose, venous, venous insufficiency, stripping
  • 1. Oduber CE, van der Horst CM, Chantal MAM, Hennekam RC. Klippel-Trenaunay syndrome: diagnostic criteria and hypothesis on etiology. Ann Plast Surg 2008;60:217-23.
  • 2. Spencer L, Quarmby JW. Klippel-Trenaunay Syndrome and left iliac vein agenesis. EJVES Extra 2007;13:50-1.
  • 3. Delis KT, Gioviczki P, Wennberg PW, Rooke TW, Driscoll DJ. Hemodynamic impairment, venous segmental disease, and clinical severity scoring in limbs with Klippel-Trenaunay syndrome. J Vasc Surg 2007;45:561-7.
  • 4. Bircher AJ, Koo JY, Frieden IJ, Berger TG. Angiodysplastic syndrome with capillary and venous malformation associated with soft tissue hypotrophy. Dematology 1994;189:292-8.
  • 5. Ada F, Aydın A, Emren SV, Çelik E. A rare lateral embriyonic varicose vein surgery in Klippel-Trenaunay Syndrome with brief review of the literature. Int J Contemp Med Res 2016;3:710-1.
  • 6. Garzon M, Huang JT, Enjolras O, Frieden IJ. Vascular malformations. J Am Acad Dermatol 2007;56:541-7.
  • 7. Zea MI, Hanif M, Habib M, Ansari A. Klippel-Trenaunay sydrome: a case report with brief review of literatüre. J Dermatol Case Rep 2009;3:56-9.
  • 8. Gloviczki P, Holler LH, Telander RL, Kaufman B, Bianco AJ, Stickler GB. . Surgical implication of Klippel-Trenaunay syndrome. Ann Surg 1983;197:353-62.
  • 9. Stephen E, Kota AA, Agarwal S, Selvaraj D, Premkumar P, Ponraj S, et al. Lateral marginal vein: have we understood its significance? Indian J Vasc Endovasc Surg 2017;4:43-5.
  • 10. Redondo P, Bastarrika G, Aguado L, Martinez-Cuesta A, Sierra A, Cabrera J, et al. Foot or hand malformations related to deep venous system anomalies of the lower limb in Klippel-Trenaunay syndrome. J Am Acad Dermatol 2009;61:621-8.
  • 11. Usta S, Guday M. Klippel-Trenaunay syndrome. Turk Gogus Kalp Dama 2013;21:179-82.
  • 12. Premkumar P, Stephen E, John JM, Kota AA, Samuel V, Selvaraj D, et al. Managment of Klippel-Trenaunay syndrome from a single center in India: experience shared. Indian J Vasc Endovasc Surg 2018;5:149-53.
  • 13. Banzic I, Brankovic M, Maksimović Ž, Davidović L, Marković M, Rančić Z. Parkes Weber syndrome-Diagnostic and management paradigms: a systematic review. Phlebology 2017;32:371-83.
Primary Language en
Subjects Cardiac and Cardiovascular Systems
Journal Section Case Reports

Orcid: 0000-0002-0015-3280
Author: Ersin ÇELİK (Primary Author)
Institution: Department of Cardiovascular Surgey, Isparta City Hospital, Isparta, Turkey
Country: Turkey

Orcid: 0000-0003-1860-7620
Author: İlker ALAT
Institution: Department of Cardiovascular Surgey, Afyonkarahisar State Hospital, Afyonkarahisar, Turkey
Country: Turkey


Application Date : November 8, 2018
Acceptance Date : October 16, 2019
Publication Date : March 4, 2020

EndNote %0 The European Research Journal Three cases with Klippel-Trenaunay syndrome and treatment options %A Ersin Çeli̇k , İlker Alat %T Three cases with Klippel-Trenaunay syndrome and treatment options %D 2020 %J The European Research Journal %P -2149-3189 %V 6 %N 2 %R doi: 10.18621/eurj.480577 %U 10.18621/eurj.480577