Year 2020, Volume 6 , Issue 4, Pages 300 - 307 2020-07-04

The evaluation of relation between vitamin B12 and body mass index

Eray ATALAY [1] , Nurullah ASLAN [2] , Pınar ŞİŞMAN [3]

Objectives: Obesity has become a pandemy all around the world, etiology of obesity consist multiple factors and it causes serious health problems. It is known that the low level of vitamin B12 has adverse effects on many systems, mainly cell DNA. In our study, it was planned to evaluate whether there is a relation between body mass index and serum vitamin B12 level.

Methods: We included 168 patients aged 18-67 years, who did not have a chronic disease and who applied to the outpatient clinic in our center. We divided the patients into 3 groups according to the body mass index (BMI): Group I: normal weight (BMI: 18.50-24.99 kg/m2); Group II: overweight (BMI: 25-29.9 kg/m2) and Group III: obese (BMI: ≥ 30 kg/m2). Vitamin B12 levels were evaluated between these groups.

Results: There was a statistically significant difference between the groups in terms of glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglyceride. Vitamin D levels were not statistically significant between the groups. The mean serum vitamin B12 levels of the individuals were 299 ± 125 pmol/L, 298 ± 148 pmol/L and 313 ± 143 pmol/L in Group I, Group II and Group III, respectively. There was no statistically significant difference and correlation between BMI and serum vitamin B12 levels in the groups.

Conclusions: The etiology of obesity, a serious health problem in today's society, has proven to be multifactorial. No significant association was found between BMI and vitamin B12 levels at the end of the study. It was concluded that similar studies should be performed with a large case series.

vitamin B12, cobalamin, obesity, body mass index
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Primary Language en
Subjects Endocrinology and Metabolism, General and Internal Medicine
Journal Section Original Articles

Orcid: 0000-0002-9700-7019
Author: Eray ATALAY
Institution: Department of Internal Medicine, Kafkas University of School of Medicine, Kars, Turkey
Country: Turkey

Orcid: 0000-0002-0925-0669
Author: Nurullah ASLAN
Institution: Department of Internal Medicine, Siverek State Hospitak, Şanlıurfa, Turkey
Country: Turkey

Orcid: 0000-0002-6561-6207
Author: Pınar ŞİŞMAN (Primary Author)
Institution: Department of Endocrinology and Metabolism, Bursa Medicana Hospital, Bursa, Turkey
Country: Turkey


Publication Date : July 4, 2020

EndNote %0 The European Research Journal The evaluation of relation between vitamin B12 and body mass index %A Eray Atalay , Nurullah Aslan , Pınar Şi̇şman %T The evaluation of relation between vitamin B12 and body mass index %D 2020 %J The European Research Journal %P -2149-3189 %V 6 %N 4 %R doi: 10.18621/eurj.478183 %U 10.18621/eurj.478183