The effectiveness of oral protein supplementation in malnourished peritoneal dialysis patients

Year 2021, Volume: 7 Issue: 2, 192 - 195, 04.03.2021

Mehmet Usta Alparslan Ersoy Yavuz Ayar

https://doi.org/10.18621/eurj.672787

Abstract

Objectives: Malnutrition is a common problem in chronic renal disease patients during pre-dialysis and dialysis, leading to increased cardiovascular diseases and mortality. This study aimed to evaluate the efficacy of supplemental protein supplementation on malnutrition in peritoneal dialysis patients.

Methods: Eighty-four stable adult peritoneal dialysis patients included in this study. In addition to the standard diets, oral nutritional product (372 calories, 61 g protein, 30 g glutamine, and 30 g arginine/100 g powder sachet twice a day) gave to patients. Before the study and after three months from the supportive therapy; anthropometric measurements with serum urea, creatinine, total protein, albumin, cholesterol, KtV, body mass index was analyzed.

Results: The mean age of peritoneal dialysis patients was 60 (46-78) years. Serum urea levels from 96 ± 44 to 109 ± 42 mg/dL (p = 0.007), total protein levels from 5.85 ± 0.68 to 6.18 ± 0.66 g/dL (7.8%, p = 0.007), albumin levels increased from 3.02 ± 0.27 to 3.32 ± 0.34 g/dL (11.7%, p = 0.003) increased significantly after an average of 0.43 g/kg protein and 178 cal/day energy support.

Conclusions: Albumin is an indicator of malnutrition related mortality. Therefore, using of protein nutritional products in addition to standard treatment may be beneficial for malnourished peritoneal dialysis patients.

Keywords

Peritoneal dialysis, malnutrition, albumin, protein supplementation

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