Year 2021, Volume 7 , Issue 2, Pages 177 - 183 2021-03-04

Outcomes of thyroid operations in patients of different age groups

Ali ÇİFTÇİ [1] , Çağrı TİRYAKİ [2]


Objectives: To determine the effects of age on preoperative findings and on outcomes of thyroid surgeries.

Methods: In this retrospective study, we analyzed the demographics, surgical and pathological data, postoperative complications and biochemical results including calcium, phosphorus and parathyroid hormone (PTH) levels of patients who undertaken thyroid operations.

Results: Totally 288 consecutive patients operated for thyroid diseases were included in the study. The patients were grouped regarding their ages as patients in the 3rd decade (n = 26), 4th decade (n = 60), 5th decade (n = 81), 6th decade (n = 77) and 7th decade (n = 44). There was not any significant difference between groups regarding the preoperative diagnoses (p = 0.09). With an advance in age, the presence of multiple nodules in preoperative period was increasing (p = 0.015). On postoperative period, the pathological diagnosis was malignant in 46 (15.9%) patients. There was not any significant difference between groups regarding the tumor type (p = 0.80). The most common tumor type was papillary carcinoma in all age groups. Postoperative complications were determined in 68 (23.6%) patients and there was not any significant difference regarding the presence of postoperative complications in all age groups (p = 0.26).

Conclusions: In conclusion, there was not any significant difference regarding postoperative outcomes in patients operated for thyroid diseases who were in the different decades of their lives. We can suggest that, thyroid surgeries are as safe in elderly patients as in younger patients.

thyroid, age, complications
  • 1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015;136:E359-86.
  • 2. Lee YS, Lee BJ, Hong HJ, Lee KD. Current trends of practical issues concerning micropapillary thyroid carcinoma: The Korean Society of Thyroid-Head and Neck Surgery. Medicine 2017;96:e8596.
  • 3. Sun GH, DeMonner S, Davis MM. Epidemiological and economic trends in inpatient and outpatient thyroidectomy in the United States, 1996-2006. Thyroid 2013;23:727-33.
  • 4. Cernea CR, Brandão LG, Hojaij FC, Carlucci DD, Montenegro FLM, Plopper C, et al. How to minimize complications in thyroid surgery? Auris Nasus Larynx 2010;37:1-5.
  • 5. Narayanan S, Arumugam D, Mennona S, Wang M, Davidov T, Trooskin SZ. An evaluation of postoperative complications and cost after short-stay thyroid operations. Ann Surg Oncol 2015;23:1440-5.
  • 6. Shevchyk IV, Cobian BA, Martinez SR. Age-based disparities in the use of total thyroidectomy for papillary thyroid carcinoma. Clin Transl Oncol 2017;19:1253-9.
  • 7. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid 2016;26:1-133.
  • 8. Molinari AS, Treiguer A, Gava, VG, Rojas JL, Evangelista PE, Gonçalves I, Treiguer A, Gava VG, et al. Thyroid surgery performed on an overnight basis: a 17 years of experience. Arch Endocrinol Metab 2015;59:434-40.
  • 9. Isik A, Firat D, Yilmaz I, Peker K, Idiz O, Yilmaz B, et al. A survey of current approaches to thyroid nodules and thyroid operations. Int J Surg 2018;54:100-4.
  • 10. Grubey JS, Raji Y, Duke WS, Terris DJ. Outpatient thyroidectomy is safe in the elderly and super-elderly. Laryngoscope 2018;128:290-4.
  • 11. Kovačić I, Kovačić M. Surgical treatment of thyroid gland in elderly patients: our experiences. Acta Med Croatica 2016;70:185-90.
  • 12. Diaconescu MR, Glod M, Costea I. Clinical features and surgical treatment of thyroid pathology in patients over 65 years. Chirurgia 2016;111:120-5.
  • 13. Canonico S, Pellino G, Pameggiani D, Sciaudone G, Candilio G, De Fatico GS, et al. Thyroid surgery in the elderly: a comparative experience of 400 patients from an Italian university hospital. Int Surg 2014;99:523-7.
  • 14. Papaleontiou M, Hughes DT, Guo C, Banerjee M, Haymart MR. Population-based assessment of complications following surgery for thyroid cancer. J Clin Endocrinol Metab 2017;102:2543-51.
  • 15. Caulley L, Johnson-Obaseki S, Luo L, Javidnia H. Risk factors for postoperative complications in total thyroidectomy: a retrospective, risk-adjusted analysis from the National Surgical Quality Improvement Program. Medicine 2017;96:e5752.
  • 16. Liu J, Sun W, Dong W, Wang Z, Zhang P, Zhang T, et al. Risk factors for post-thyroidectomy haemorrhage: a meta-analysis. Eur J Endocrinol 2017;176:591-602.
  • 17. Puzziello A, Rosato L, Innaro N, Orlando G, Avenia N, Perigli G, et al. Hypocalcemia following thyroid surgery: incidence and risk factors. A longitudinal multicenter study comprising 2,631 patients. Endocrine 2014;47:537-42.
  • 18. Liao S, Shindo M. Management of well-differentiated thyroid cancer. Otolaryngol Clin North Am 2012;45:1163-79.
  • 19. Yano Y, Sugino K, Akaishi J, Uruno T, Okuwa K, Shibuya H, et al. Treatment of autonomously functioning thyroid nodules at a single institution: radioiodine therapy, surgery, and ethanol injection therapy. Ann Nucl Med 2011;25:749-54.
  • 20. Gharib H, Papini E. Thyroid nodules: clinical importance, assessment, and treatment. Endocrinol Metab Clin North Am 2007;36:707-35.
  • 21. Caleo A, Vigliar E, Vitale M, Crescenzo VD, Cinelli M, Carlomagno C, et al. Cytological diagnosis of thyroid nodules in Hashimoto thyroiditis in elderly patients. BMC Surg 2013;13:S2-S41.
  • 22. Kavanagh J, McVeigh N, McCarthy E, Bennett K, Beddy P. Ultrasound-guided fine needle aspiration of thyroid nodules: factors affecting diagnostic outcomes and confounding variables. Acta Radiol 2017;58:301-6.
  • 23. Chiu CG, Yao R, Chan SK, Strugnel SS, Bugis S, Irvine R, et al. Hemithyroidectomy is the preferred initial operative approach for an indeterminate fine needle aspiration biopsy diagnosis. Can J Surg 2012;55:191-8.
  • 24. Liu X, Zhu L, Wang Z, Cui D, Chen H, Duan Y, et al. Evolutionary features of thyroid cancer in patients with thyroidectomies from 2008 to 2013 in China. Sci Rep 2016;22;6:28414.
  • 25. Niemann AC, Reid AT, Smith J, James Hammond J, DeBolle AS, Wei I, et al. Association of patient age with high-risk pathologic features in papillary thyroid cancer. J Surg Res 2017;211:228-32.
  • 26. Chávez Tostado KV, Velázquez-Fernandez D, Chapa M, Pantoja Millán JP, Salazar MS, Herrera MF. Substernal goiter: correlation between grade and surgical approach. Am Surg 2018;84:262-6.
  • 27. Moten AS, Thibault DP, Willis AW, Willis AI. Demographics, disparities, and outcomes in substernal goiters in the United States. Am J Surg 2016;211:703-9.
Primary Language en
Subjects Surgery
Journal Section Original Articles
Authors

Orcid: 0000-0001-8217-575X
Author: Ali ÇİFTÇİ (Primary Author)
Institution: Department of General Surgery, University of Health Sciences, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey
Country: Turkey


Orcid: 0000-0001-8484-8516
Author: Çağrı TİRYAKİ
Institution: Department of General Surgery, Buhara Hospital, Erzurum, Turkey
Country: Turkey


Dates

Application Date : June 13, 2020
Acceptance Date : November 1, 2020
Publication Date : March 4, 2021

EndNote %0 The European Research Journal Outcomes of thyroid operations in patients of different age groups %A Ali Çiftçi , Çağrı Tiryaki %T Outcomes of thyroid operations in patients of different age groups %D 2021 %J The European Research Journal %P -2149-3189 %V 7 %N 2 %R doi: 10.18621/eurj.752504 %U 10.18621/eurj.752504