Takotsubo syndrome triggered by emotional stress: a case report

Year 2022, Volume: 8 Issue: 5, 742 - 746, 04.09.2022

Emine Mülayim

https://doi.org/10.18621/eurj.898914

Abstract

Takotsubo syndrome is an acute cardiac syndrome characterized by transient systolic dysfunction of the left ventricle without coronary artery disease. It’s etiology has not been fully explained, physical and intense emotional stress triggers this syndrome so it is also called "broken heart syndrome" or "stress cardiomyopathy". Takotsubu syndrome has been reported that approximately 2% of patients presenting with acute coronary syndrome. In this case, we presented a 65-year-old patient who had a Takotsubo syndrome attack after emotional stress, thinking that it would contribute to the literature and increase awareness of this disease.

Keywords

Takotsubo syndrome, stress cardiomyopathy, emotional stress, somatic stress

References

• 1. Prasad A, Lerman A, Rihal CS. Apical ballooning syndrome (Takotsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J 2008;155:408-17.
• 2. Sato H, Tateishi H, Uchida T, Kodama K, Hon M. Takotsubo type cardiomyopathy due to multivessel spasm. In: Kodama K, Haze K, Hon M, editors. Clinical aspect of myocardial injury: from ischemia to heart failure. Kagaku Hyoronsha; Tokyo;1990: pp. 56-64. [in Japanese]
• 3. Nayeri A, Rafla-Yuan E, Farber-Eger E, Blair M, Ziaeian B, Cadeiras M, et al. Pre-existing psychiatric illness is associated with increased risk of recurrent Takotsubo cardiomyopathy. Psychosomatics 2017;58:527-32.
• 4. Redfors B, Shao Y, Omerovic E. Stress-induced cardiomyopathy (Takotsubo) broken heart and mind? Vasc Health Risk Manag 2013;9:149-54.
• 5. Akashi YJ, Nef HM, Lyon AR. Epidemiology and patho-physiology of Takotsubo syndrome. Nat Rev Cardiol 2015;12:387-97.
• 6. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Press. 2013.
• 7. Oliveri F, Goud HK, Mohammed L, Mehkari Z, Javed M, Althwanay A, et al. Role of depression and anxiety disorders in Takotsubo Syndrome: the psychiatric side of broken heart. Cureus 2020:12:e10400.
• 8. Y-Hassan S, Tornvall P. Epidemiology, pathogenesis and management of Takotsubo syndrome. Clin Auton Res 2018;28:53-65.
• 9. Elsayed M, Connemann BJ, Dahme T, Tesfay T, Gahr M. Takotsubo cardiomyopathy with inconspicuous initial electrocardiogram: a potentially serious cardiac pathology related to emotional stress. Front Pschiatry 2019;10:308.
• 10. Summers MR, Lennon RJ, Prasad A. Pre-morbid psychiatric and cardiovascular diseases in apical ballooning syndrome (Takotsubo/ stress-induced cardiomyopathy): potential pre-disposing factors? J Am Coll Cardiol 2010;55:700-1.
• 11. Jenab Y, Hashemi SR, Ghaffari-Marandi N, Zafarghandi H, Shahmansouri N. Psychological features of Takotsubo cardiomyopathy: report of four cases. J Tehran Heart Cent 2017;12:95-8.
• 12. Wang X, Pei J, Hu X. The brain-heart connection in Takotsubo syndrome: the central nervous system, sympathetic nervous system, and catecholamine overload. Cardiol Res Pract 2020;2020:4150291.
• 13. Nef HM, Möllmann H, Kostin S, Troidl C, Voss S, Weber M, et al. Takotsubo cardiomyopathy: intraindividual structural analysis in the acute phase and after functional recovery. Eur Heart J 2007;28:2456-64.
• 14. Deshmukh A, Kumar G, Pant S, Rihal C, Murugiah K, Mehta JL. Prevalence of Takotsubo cardiomyopathy in the United States. Am Heart J 2012;164:66-71.
• 15. El-Sayed AM, Brinjikji W, Salka S. Demographic and comorbid predictors of stress (Takotsubo) cardiomyopathy. Am J Cardiol 2012;110:1368-72.
• 16. Toussi A, Bryk J, Alam A. Forgetting heart break: a fascinating case of transient left ventricular apical ballooning syndrome associated with dissociative amnesia. Gen Hosp Psychiatry 2014;36:225-7.
• 17. Maldonado JR, Pajouhi P, Witteles R. Broken heart syndrome (Takotsubo cardiomyopathy) triggered by acute mania: a review and case report. Psychosomatics 2013;54:74-9.
• 18. Chandra PA, Golduber G, Chuprun D, Chandra AB. Takotsubo cardiomyopathy following electroconvulsive therapy. J Cardiovas Med 2009;10:333-5.
• 19. Verduin MI. Commentary on 2 cases of Takotsubo cardiomyopathy involving psychotropic medication. J Psychiatr Pract 2016;22:239-40.