Evaluation of pediatric patients installed due to acute gastroenteritis

Year 2023, Volume: 9 Issue: 6 - November 2023, 1392 - 1397, 04.11.2023

Özhan Orhan , Mehmet Bulut

https://doi.org/10.18621/eurj.1261344

Abstract

Objectives: Acute gastroenteritis is one of the most prevalent causes of death and morbidity in children and a significant health issue in Turkey, as well as developed and developing nations. The purpose of this study is to analyze retrospectively the patients with acute gastroenteritis who sought treatment at the Kızıltepe State Hospital in Mardin.

Methods: This study was designed as a single-center retrospective study in which demographic variables were evaluated by taking fresh stool samples from the patients who applied to the Mardin Province Kızıltepe State Hospital between 01/11/2020 and 31/10/2021 with the complaint of diarrhea. The information of rotavirus, enteric adenovirus and amoeba viruses in stool samples was investigated by qualitative immunochromatographic test. The researcher assessed the research data utilizing the hospital's file archive materials and three factors set by the researcher. The researcher extracted the information about these factors from the patient files and stored it in a Microsoft Office Excel file.

Results: According to the gender variable of the research participants, Amoeba positive rates were considerably higher in males than in girls (35.8% versus 22.6%, p = 0.046, respectively). According to the age groups variable, rotavirus antigen positive was statistically significantly greater in the 5-24 month age group compared to other age groups (p = 0.034). Similarly, Amoeba positive was statistically substantially higher in the 5-24 month age group compared to other age groups (p = 0.001). There was no significant variation between age groups in the distribution of adenovirus. According to the seasonal variable, rotavirus antigen positivity was most prevalent in the spring, and the difference between the spring and other seasons was statistically significant (p = 0.001), whereas amoeba positivity was most prevalent in the summer, with no statistically significant difference between the seasons (p = 0.003). The frequency of undiscovered variables was greater during the spring-summer months, and a statistically significant difference (p = 0.041) was identified between the groups. The seasonal variation in the prevalence of Adenovirus antigen positive was not statistically significant (p = 0.394).

Conclusions: As a result, in poor and underdeveloped nations, it is among the top five causes of death in children under the age of five, in relation to acute gastroenteritis. Furthermore, the majority of these deaths may be minimized by preventative and prevention strategies. It is the responsibility of governments, health professionals, and families to foster a safe and healthy environment for all infants and children during their infancy and development. Community-based health strategies should be undertaken to lower the morbidity and death rates of millions of people worldwide who are exposed to harmful environmental conditions and malnutrition.

Keywords

Acute gastroenteritis, kid, adenovirus, rotavirus, amoeba

References

• 1. Conk Z, Başbakkal Z, Bal Yılmaz H, Bolışık B. Pediatri hemşireliği. Akademisyen Tıp Kitapevi, Ankara. 2013.
• 2. Kliegman RM, Stanton BF, III JWSG, Schor NF, Behrman RE. Nelson Textbook of Pediatrics. 20 ed. Canada: Elsevier. 2016.
• 3. WHO. Ending Preventable Child Deaths from Pneumonia and Diarrhoea by 2025 The integrated Global Action Plan for Pneumonia and Diarrhoea (GAPPD). 2014.
• 4. Clasen T, Prüss-Ustün A, Mathers C, Cumming O, Cairncross S, Colford JM. Estimating the impact of unsafe water, sanitation and hygiene on the global burden of disease: evolving and alternative methods. Trop Med Int Health 2014;19:884-93.
• 5. WHO. Diarrhoeal disease [database on the Internet]. 2022.https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease.
• 6. Çoban B, Topal B. Evaluation of rotavirus gastroenteritis in children: five years’ surveillance in Alanya, Antalya. Turk J Pediatr 2014;56:280-4.
• 7. Güler Ç, Akın L. Halk Sağlığı Temel Bilgiler Cilt III. Ankara: Hacettepe Üniversitesi Yayınları. 2012.
• 8. Saç R, Dallar Y, Sarıyıldız E, Aral Y. Z, Acar B. [Comparison of clinical estimation and actual dehydration in children with acute gastroenteritis]. Ege Tıp Dergisi 2008;47:187-92. [Article in Turkish]
• 9. Kotloff KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, et al. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study. Lancet 2013;382;209-22.
• 10. Guarino A, Ashkenazi S, Gendrel D, Lo Vecchio A, Shamir R, Szajewska H, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition/European Society for Pediatric Infectious Diseases evidence-based guidelines for the management of acute gastroenteritis in children in Europe: update 2014. J Pediatr Gastroenterol Nutr 2014;59:132-52.
• 11. WHO. Diarrhoeal disease [database on the Internet]. 2017. http://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease.
• 12. Payne DC, Parashar UD, Lopman BA. Developments in understanding acquired immunity and innate susceptibility to norovirus and rotavirus gastroenteritis in children. Curr Opin Pediatr 2015;27:105-12.
• 13. Prüss-Ustün A, Wolf J, Bartram J, Clasen T, Cumming O, Freeman MC, et al. Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes: an updated analysis with a focus on low-and middle-income countries. Int J Hyg Environ Health 2019;222:765-77.
• 14. Öztürk R. Akut İshal, Etyoloji, Patogenez, Tanı ve Tedavi, İ. Ü. Cerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Etkinlikleri, Türkiye’de Sık Karşılaşılan Hastalıklar I, Enfeksiyon Hastalıkları, Romatizmal Hastalıklar, Afetlerde Azimle Yaralanmaları Sempozyum Dizisi 2007:55;175-94.
• 15. Bulut Y, İşeri L, Ağel E, Durmaz B. [The positivity of rotavirus in children with suspected acute gastroenteritis . İnönü Üniversitesi Tıp Fakültesi Dergisi 2003;10:143-5. [Article in Turkish]
• 16. Altındiş M. Konya Bölgesi 0-5 Yaş Grubu Rotavirüs Enfeksiyonlarının Seroepidemiyolojisi ve 0-3 Yaş Arası İshalli Çocuklarda Rotavirüs Enfeksiyonlarının Lateks, ELISA ve Poliakrilamid Jel Elektroforez (PAGE) Teknikleri İle Araştırılması. S.Ü. SBE Veteriner Viroloji Doktora tezi, Konya, 2002.
• 17. Parashar UD, Gibson CJ, Bresse JS, Glass RI. Rotavirus and severe childhood diarrhea. Emerg Infect Dis 2006;12:304-6.
• 18. Yıldırmak Y, Tanyer G, Dallar Y, Serdaroğlu A. [The clinical and epidemiological features in acute gastroenteritis due to rotavirus and other ethiologic agents in infants]. Turkiye Klinikleri J Pediatr. 1992;1:1-6. [Article in Turkish]
• 19. Gül M, Garipardıç M, Çıragil P, Aral M, Karabiber H, Güler İ. [Investigation of rotavirus and adenovirus types 40/41 in children with gastroenteritis between 0-5 years of age]. ANKEM Derg 2005;19:64-67. [Article in Turkish]
• 20. Dennehy PH. Acute diarrheal disease in children: epidemiology, prevention, and treatment. Infect Dis Clin North Am 2005:19:585-602.
• 21. Bernstein DI, Ward RL. Rotaviruses. In: Feigin RD, Cherry JD. Demmler GJ Kaplan SL, eds., Textbook Pediatric Infectious Diseases. 5th ed., Philadelphia:Saunders 2004: pp. 2110-33.
• 22. Matson DO. Rotaviruses. In: Long SS, Pickering LK, Prober CG, eds., Principles and Practices of Pediatric Infectious Diseases, 2nd ed., New York: Churchill Livingstone, 2003: pp. 1105-9.
• 23. Ramsay M, Brown D. Epidemiology of group a rotaviruses. In: Gray J, Desselberger U, eds., Rotaviruses: Methods and Protocols. Humana Press Inc: Totowa, NJ, 2000: pp. 217-36.
• 24. Cohen MB, Laney DW. Infectious diarrhea. In: Wyllie R Hyams JS. Eds., Pediatric gastrointestinal disease: pathophysiology, diagnosis, management. WB Saunders: Philadelphia,1999: pp. 348-70.
• 25. Akdoğan D, Çınar S, Şahin İ, Per H, Kılıç H. [Investigation of rotavirus in diarrhea in children aged 0-5 years]. İnfeksiyon Dergisi 2001;15:291-4. [Article in Turkish]
• 26. Akıncı N, Ercan TE, Yalman N. [Adenovirus and rotavirus in children with acute gastroenteritis]. Çocuk Enfeksiyon Dergisi 2007;1:98-101. [Article in Turkish]
• 27. Öztürk R. Reovirüs ailesi ve diğer gastroenterit akut gastroenteritli çocuk hastalarda rotavirus sıklığı virüsları, Topçu WA, Söyletir G, Doğanay M (eds.). İnfeksiyon Hastalıkları ve Mikrobiyolojisi. 2. ed., Nobel Tıp Kitabevi: İstanbul, 2002: pp. 1226-31.
• 28. Bayraktar B, Toksoy B, Bulut E. [Detection of rotavirus and adenovirus in children with acute gastroenteritis]. Klimik Derg 2010;23:15-7. [Article in Turkish]