Research Article
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Year 2022, , 74 - 79, 22.08.2022
https://doi.org/10.26650/experimed.1104796

Abstract

Supporting Institution

İstanbul Üniversitesi-Cerrahpaşa

Project Number

FYL-2017-22991

Thanks

İstanbul Üniversitesi-Cerrahpaşa BAP birimine teşekkürlerimizi sunarız.

References

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  • 4. Sax L. Polyethylene terephthalate may yield endocrine disruptors. Environ Health Perspect 2010; 118(4): 445-8. [CrossRef] google scholar
  • 5. Calafat AM, Ye X, Wong LY, Reidy JA, Needham LL. Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 20032004. Environ Health Perspect 2008; 116(1): 39-44. [CrossRef] google scholar
  • 6. Vom Saal FS, Akingbemi BT, Belcher SM, Birnbaum LS, Crain DA, Eriksen M et al. Chapel Hill bisphenol A expert panel consensus statement: Integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod Toxicol 2007; 24(2): 131. [CrossRef] google scholar
  • 7. Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Di(2-ethylhexyl)phthalate. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 2002. google scholar
  • 8. Latini G. Monitoring phthalate exposure in humans. Clinica Chim-ica Acta 2005; 361(1-2): 20-9. [CrossRef] google scholar
  • 9. Borrell B. Toxicology: the big test for bisphenol A. Nature 2010; 464: 1122-4. [CrossRef] google scholar
  • 10. Khetan SK. Environmental chemicals targeting estrogen signaling pathways. Endocrine Disruptors in the Environment, First Edition. Hoboken, New Jersey: John Wiley & Sons, Inc., 2014; 67-8. google scholar
  • 11. Vandenberg LN, Maffni MV, Sonnenschein C, Rubin BS, Soto AM. Bisphenol-A and the great divide: A review of controversies in the field of endocrine disruption. Endocr Rev 2009; 30(1): 75-95. [CrossRef] google scholar
  • 12. Kavlock RJ, Daston GP, DeRosa C, Fenner-Crisp P, Gray LE, Kaat-tari S et al. Research needs for the risk assessment of health and environmental effect of endocrine disruptors: a report of the U.S. EPA-sponsored workshop, Environ Health Perspect 1996; 104(Suppl 4): 715-40. [CrossRef] google scholar
  • 13. World Health Organization (WHO). Guidelines for Drinking-Water Quality. Fourth Edition. Malta, 2011. google scholar
  • 14. U.S. Food and Drug Administration (FDA). Beverages: bottled wa-ter quality standard; establishing an allowable level for di (2- eth-ylhexyl) phthalate. Small entity compliance guide. Rockville, 2012. google scholar
  • 15. Amiridou D, Voutsa D. Alkylphenols and phthalates in bottled wa-ters. Jour. Hazard Mater 2011; 185(1): 281-6. [CrossRef] google scholar
  • 16. Keresztes S, Tatar E, Czegeny Z, Zaray G, Mihucz VG. Study on the leaching of phthalates from polyethylene terephthalate bottles into mineral water. Sci Total Environ 2013; 458-460: 451-8. [CrossRef] google scholar
  • 17. Evandri MG, Tucci P, Bolle P. Toxicological evaluation of commer-cial mineral water bottled in polyethylene terephthalate: a cyto-genetic approach with Allium cepa. Food Addit Contam 2000; 17(12): 1037-45. [CrossRef] google scholar
  • 18. Linssen J, Reitsma H, Cozijsen J. Static headspace gas chromatography of acetaldehyde in aqueous foods and polythene terephthalate. Z Lebensm Unters Forsch 1995; 201(3): 253-5. [CrossRef] google scholar
  • 19. Biscardi D, Monarca S, De Fusco R, Senatore F, Poli P, Buschini A et al. Evaluation of the migration of mutagens/carcinogens from PET bottles into mineral water by Tradescantia/micronuclei test, Comet assay on leukocytes and GC/MS. Sci Total Environ. 2003; 302(1-3): 101-8. [CrossRef] google scholar
  • 20. Guart A, Bono-Blay F, Borrell A, Lacorte S. Effect of bottling and storage on the migration of plastic constituents in Spanish bot-tled waters. Food Chem 2014; 156: 73-80. [CrossRef] google scholar
  • 21. Zaki G, Shoeib T. Concentrations of several phthalates contami-nants in Egyptian bottled water: Effects of storage conditions and estimate of human exposure. Sci Total Environ 2018; 618: 142-50. [CrossRef] google scholar
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  • 23. WHO Guidelines for drinking-water quality. Third edition. World Health Organization, Geneva, 2008; 1. google scholar
  • 24. Amiridou D, Voutsa D. Alkylphenols and phthalates in bottled wa-ters. Jour Hazard Mater 2011; 185(1): 281-86. [CrossRef] google scholar
  • 25. Greifenstein M, White DW, Stubner A, Hout J, Whelton AJ. Impact of temperature and storage duration on the chemical and odor quality of military packaged water in polyethylene terephthalate bottles. Sci Total Environ 2013; 456-457: 376-83. [CrossRef] google scholar
  • 26. Commission directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs. Off Jour Eur Commun 2002; 220:18-58. google scholar
  • 27. Maragou NC, Makri A, Lampi EN, Thomaidis NS, Koupparis MA. Migration of bisphenol A from polycarbonate baby bottles under real use conditions. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2008; 25(3): 373-83. [CrossRef] google scholar
  • 28. Guart A, Bono-Blay F, Borrell A, Lacorte S. Migration of plasticizer phthalates, bisphenol A and alkylphenols from plastic containers and evaluation of risk. Food Addit Contam Part A Chem Anal Con-trol Expo Risk Assess 2011; 28(5): 676-85. [CrossRef] google scholar
  • 29. Nerin C, Fernandez C, Domeno C, Salafranca J. Determination of potential migrants in polycarbonate containers used for micro-wave ovens by high- performance liquid chromatography with ultraviolet and fluorescence detection. J Agric Food Chem 2003; 51(19): 5647-53. [CrossRef] google scholar

The Effect of Different Storage Conditions on The Migration of Chemicals from Polyethylene Terephthalate and Polycarbonate Bottles to Water

Year 2022, , 74 - 79, 22.08.2022
https://doi.org/10.26650/experimed.1104796

Abstract

Objective: Polyethylene terephthalate (PET) and polycarbonate (PC) bottles have been used widely in the last years for the consumption of water and the increased use of these chemicals has raised many concerns regarding their adverse effects on health. Phthalates and bisphenol A (BPA) are the main endocrine disrupting chemicals (EDCs) that can migrate from these plastics into potable water.

Materials and Methods: The concentrations of phthalate and BPA were measured in water samples that were stored in PET and PC bottles at different storage conditions. The method of ELISA was used for the determination of phthalate and BPA levels. A standard curve is obtained from the standards prepared at known concentrations of phthalate, BPA, according to their absorbance at 450 nm. The BPA levels of the samples were obtained through the calculation of the absorbance values acquired using the standard curve.

Results: Different storage and heating processes applied on the samples significantly increased the levels of BPA and phthalate. One year of storage led to a statistically significant increase in phthalate levels when compared to the control group. Both BPA and phthalate levels detected in the water samples were higher than the control group depending on the storage conditions including exposure to high temperatures, sunlight and outdoor conditions.

Conclusion: Our results indicate the necessity to establish the environmental conditions that must be ensured during the production, transportation and storage processes of the bottles, on a legal basis with legal regulations.

Project Number

FYL-2017-22991

References

  • 1. Guyton AC, Hall JE. Introduction to Endocrinology. Hall JE. Text-book of Medical Physiology. Philadelphia: Saunders, 2011; 881. google scholar
  • 2. Jarvis E, Campbell NA, Reece JB. Hormones and the Endocrine System. Wilbur B. Biology. San Francisco: Pearson Education, 2005; 945-6. google scholar
  • 3. Cao XL, Corriveau J. Migration of bisphenol a from polycarbonate baby and water bottles into water under severe conditions. J Agric Food Chem 2008; 56(15): 6378-81. [CrossRef] google scholar
  • 4. Sax L. Polyethylene terephthalate may yield endocrine disruptors. Environ Health Perspect 2010; 118(4): 445-8. [CrossRef] google scholar
  • 5. Calafat AM, Ye X, Wong LY, Reidy JA, Needham LL. Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 20032004. Environ Health Perspect 2008; 116(1): 39-44. [CrossRef] google scholar
  • 6. Vom Saal FS, Akingbemi BT, Belcher SM, Birnbaum LS, Crain DA, Eriksen M et al. Chapel Hill bisphenol A expert panel consensus statement: Integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod Toxicol 2007; 24(2): 131. [CrossRef] google scholar
  • 7. Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Di(2-ethylhexyl)phthalate. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 2002. google scholar
  • 8. Latini G. Monitoring phthalate exposure in humans. Clinica Chim-ica Acta 2005; 361(1-2): 20-9. [CrossRef] google scholar
  • 9. Borrell B. Toxicology: the big test for bisphenol A. Nature 2010; 464: 1122-4. [CrossRef] google scholar
  • 10. Khetan SK. Environmental chemicals targeting estrogen signaling pathways. Endocrine Disruptors in the Environment, First Edition. Hoboken, New Jersey: John Wiley & Sons, Inc., 2014; 67-8. google scholar
  • 11. Vandenberg LN, Maffni MV, Sonnenschein C, Rubin BS, Soto AM. Bisphenol-A and the great divide: A review of controversies in the field of endocrine disruption. Endocr Rev 2009; 30(1): 75-95. [CrossRef] google scholar
  • 12. Kavlock RJ, Daston GP, DeRosa C, Fenner-Crisp P, Gray LE, Kaat-tari S et al. Research needs for the risk assessment of health and environmental effect of endocrine disruptors: a report of the U.S. EPA-sponsored workshop, Environ Health Perspect 1996; 104(Suppl 4): 715-40. [CrossRef] google scholar
  • 13. World Health Organization (WHO). Guidelines for Drinking-Water Quality. Fourth Edition. Malta, 2011. google scholar
  • 14. U.S. Food and Drug Administration (FDA). Beverages: bottled wa-ter quality standard; establishing an allowable level for di (2- eth-ylhexyl) phthalate. Small entity compliance guide. Rockville, 2012. google scholar
  • 15. Amiridou D, Voutsa D. Alkylphenols and phthalates in bottled wa-ters. Jour. Hazard Mater 2011; 185(1): 281-6. [CrossRef] google scholar
  • 16. Keresztes S, Tatar E, Czegeny Z, Zaray G, Mihucz VG. Study on the leaching of phthalates from polyethylene terephthalate bottles into mineral water. Sci Total Environ 2013; 458-460: 451-8. [CrossRef] google scholar
  • 17. Evandri MG, Tucci P, Bolle P. Toxicological evaluation of commer-cial mineral water bottled in polyethylene terephthalate: a cyto-genetic approach with Allium cepa. Food Addit Contam 2000; 17(12): 1037-45. [CrossRef] google scholar
  • 18. Linssen J, Reitsma H, Cozijsen J. Static headspace gas chromatography of acetaldehyde in aqueous foods and polythene terephthalate. Z Lebensm Unters Forsch 1995; 201(3): 253-5. [CrossRef] google scholar
  • 19. Biscardi D, Monarca S, De Fusco R, Senatore F, Poli P, Buschini A et al. Evaluation of the migration of mutagens/carcinogens from PET bottles into mineral water by Tradescantia/micronuclei test, Comet assay on leukocytes and GC/MS. Sci Total Environ. 2003; 302(1-3): 101-8. [CrossRef] google scholar
  • 20. Guart A, Bono-Blay F, Borrell A, Lacorte S. Effect of bottling and storage on the migration of plastic constituents in Spanish bot-tled waters. Food Chem 2014; 156: 73-80. [CrossRef] google scholar
  • 21. Zaki G, Shoeib T. Concentrations of several phthalates contami-nants in Egyptian bottled water: Effects of storage conditions and estimate of human exposure. Sci Total Environ 2018; 618: 142-50. [CrossRef] google scholar
  • 22. https://www.epa.gov/sites/production/files/2015-10/docu-ments/20110503-11-p- 0215.pdf (20.04.2018). google scholar
  • 23. WHO Guidelines for drinking-water quality. Third edition. World Health Organization, Geneva, 2008; 1. google scholar
  • 24. Amiridou D, Voutsa D. Alkylphenols and phthalates in bottled wa-ters. Jour Hazard Mater 2011; 185(1): 281-86. [CrossRef] google scholar
  • 25. Greifenstein M, White DW, Stubner A, Hout J, Whelton AJ. Impact of temperature and storage duration on the chemical and odor quality of military packaged water in polyethylene terephthalate bottles. Sci Total Environ 2013; 456-457: 376-83. [CrossRef] google scholar
  • 26. Commission directive 2002/72/EC of 6 August 2002 relating to plastic materials and articles intended to come into contact with foodstuffs. Off Jour Eur Commun 2002; 220:18-58. google scholar
  • 27. Maragou NC, Makri A, Lampi EN, Thomaidis NS, Koupparis MA. Migration of bisphenol A from polycarbonate baby bottles under real use conditions. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2008; 25(3): 373-83. [CrossRef] google scholar
  • 28. Guart A, Bono-Blay F, Borrell A, Lacorte S. Migration of plasticizer phthalates, bisphenol A and alkylphenols from plastic containers and evaluation of risk. Food Addit Contam Part A Chem Anal Con-trol Expo Risk Assess 2011; 28(5): 676-85. [CrossRef] google scholar
  • 29. Nerin C, Fernandez C, Domeno C, Salafranca J. Determination of potential migrants in polycarbonate containers used for micro-wave ovens by high- performance liquid chromatography with ultraviolet and fluorescence detection. J Agric Food Chem 2003; 51(19): 5647-53. [CrossRef] google scholar
There are 29 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Article
Authors

Gumrah Seyhan This is me 0000-0002-2626-1757

Unsal Veli Ustundag 0000-0003-0804-1475

Ismail Unal This is me 0000-0002-8664-3298

Perihan Seda Ates Kalkan This is me 0000-0002-4905-1912

Derya Cansız This is me 0000-0002-6274-801X

Ebru Emekli Alturfan 0000-0003-2419-8587

Ata Alturfan 0000-0003-0528-9002

Project Number FYL-2017-22991
Publication Date August 22, 2022
Submission Date April 17, 2022
Published in Issue Year 2022

Cite

Vancouver Seyhan G, Ustundag UV, Unal I, Ates Kalkan PS, Cansız D, Emekli Alturfan E, Alturfan A. The Effect of Different Storage Conditions on The Migration of Chemicals from Polyethylene Terephthalate and Polycarbonate Bottles to Water. Experimed. 2022;12(2):74-9.