The Mitochondrial Origins of the Hellenistic Individuals of Ayasuluk Hill
Abstract
Objective: The present study aimed to extract ancient DNA from the remains of three individuals from the 4th century BC in order to determine the haplogroups through a mitochondrial DNA study, thus providing information about Anatolian migrations in ancient times.
Materials and Methods: For this purpose, the study examined the remains of three bodies found at the bottom of the city walls from the archeological excavations between 2007-2008 and dated to the 4th century BC. After taking anthropometric measurements, the study examined the mitochondrial HVR1 and HVR2 regions by using Sanger sequencing and then used online programs to evaluate the data from the sequencing.
Results: As a result of the study, death due to a possible injury from a sharp object was observed on the right femur of one of the three individuals. The maternal haplogroups of the individuals were determined to belong to the T2b group of European origin.
Conclusion: The present study obtained genetic information regarding three individuals found at the bottom of the ancient city walls on Ayasuluk Hill. These results will provide important information about the commander of the ruins found on the walls of the Ayasuluk Hill of the ancient city of Ephesus, which constantly changed hands during the Wars of the Diadochi.
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References
- 1. Marciniak S, Perry GH. Harnessing ancient genomes to study the history of human adaptation. Nat Rev Genet 2017; 18(11): 659-74. [CrossRef] google scholar
- 2. Quintana-Murci L. Genetic, linguistic and archaeological perspectives on human diversity in Southeast Asia. Am J Hum Genet 2002; 71(5): 1253-5. [CrossRef] google scholar
- 3. De Chadarevian S. Genetic evidence and interpretation in history. BioSocieties 2010; 5(3): 301-5. [CrossRef] google scholar
- 4. Posth C, Nakatsuka N, Lazaridis I, Skoglund P, Mallick S, Lamnidis TC, et al. Reconstructing the deep population history of Central and South America. Cell 2018; 175(5): 1185-97. [CrossRef] google scholar
- 5. Moreno-Mayar JV, Vinner L, de Barros Damgaard P, De La Fuente C, Chan J, Spence JP, et al. Early human dispersals within the Americas. Science 2018; 362(6419): eaav2621. [CrossRef] google scholar
- 6. Feldman M, Master DM, Bianco RA, Burri M, Stockhammer PW, Mittnik A, et al. Ancient DNA sheds light on the genetic origins of early Iron Age Philistines. Sci Adv 2019; 5(7): eaax0061. [CrossRef] google scholar
- 7. Kaya MA. Anadolu'daki Galatlar ve Galatya tarihi: Ege Üniversitesi; 2000. google scholar
- 8. Brandstätter A, Niederstätter H, Parson W. Monitoring the inheritance of heteroplasmy by computer-assisted detection of mixed basecalls in the entire human mitochondrial DNA control region. Int J Legal Med 2004; 118(1): 47-54. [CrossRef] google scholar
Details
Primary Language
English
Subjects
Clinical Sciences
Journal Section
Research Article
Publication Date
December 31, 2022
Submission Date
October 2, 2022
Acceptance Date
November 24, 2022
Published in Issue
Year 2022 Volume: 12 Number: 3