Solitary Fibrous Tumors of the Pleura

Abstract

Objectives: The aim of this study is to evaluate the clinical behavior of the solitary fibrous tumors of pleura and the optimal surgical approach for these rare tumors. Material and Methods: We have reviewed the records of six patients who underwent tumor resection in our clinic between 1997 and 2004 retrospectively. Results: Six patients were operated in this period and the mean age was 42.3 years. None of them have been exposed to asbestosis. Symptoms were presented in five patients. All patients underwent thoracotomy. Tumor was originated from visceral pleura in five patients and parietal pleura in one. All patients underwent tumor excision. Mean diameter for tumor was 14cm (range 6 to 24). Pathology results were reported as benign solitary fibrous tumor of the pleura for all the six patients. Resection was complete in all patients. There was no postoperative mortality and major complications. No recurrence has been observed during the mean 53.5 months follow-up. Conclusion: Solitary fibrous tumors of the pleura are rare neoplasms and can reach to giant diameters. Complete surgical resection is the optimal treatment for these tumors and risk of malignancy in larger masses should be remembered. ©2007, Firat University, Medical Faculty

Keywords

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Plevranın Soliter Fibröz Tümörleri

Abstract

Giriş: Bu çalışmanın amacı plevranın soliter fibröz tümörlerinin klinik davranışını değerlendirerek nadir görülen bu tümörlerin, optimal cerrahi yöntemini belirlemektir. Gereç ve Yöntem: 1997 ve 2004 yılları arasında, kliniğimizde soliter fibröz tümör rezeksiyonu yapılan 6 hastanın kayıtları retrospektif olarak incelendi. Bulgular: Opere edilen altı hastanın yaş ortalaması 42.3 idi. Hiçbir hastada asbest temas öyküsü yoktu. Beş olgu semptomatikti. Tüm olgulara torakotomi yapıldı. Beş hastada tümör viseral plevradan, birinde ise parietal plevradan kaynaklanmaktaydı. Olgularımızda tümör total olarak eksize edildi. Ortalama tümör çapı 14 cm (6-24) idi. Patoloji sonuçları altı olguda da plevranın benign soliter fibröz tümörü olarak raporlandı. Olguların hepsinde komplet rezeksiyon yapıldı. Postoperatif mortalite ve major komplikasyon saptanmadı. Ortalama 53.5 aylık takipte rekürrens gözlenmedi. Sonuç: Plevranın soliter fibröz tümörleri nadir görülen neoplazmalardır ve büyük boyutlara ulaşabilir. Komplet cerrahi rezeksiyon, bu tümörlerin optimal tedavisidir ve büyük kitlelerde malignite akılda tutulmalıdır. ©2007, Fırat Üniversitesi, Tıp Fakültesi

Keywords

• Soliter fibröz tümör, plevra, komplet rezeksiyon

References

1. de Perrot M, Fischer S, Brundler MA, Sekine Y, Keshavjee S. Solitary fibrous tumors of the pleura. Ann Thorac Surg 2002; 74:285-93.
2. de Perrot M, Kurt AM, Robert JH, Borisch B, Spiliopoulos A. Clinical behavior of solitary fibrous tumors of the pleura. Ann Thorac Surg 1999; 67: 1456-9.
3. Sung SH, Chang JW, Kim J, Lee KS, Han J, Park SI. Solitary fibrous tumors of the pleura: surgical outcome and clinical course. Ann Thorac Surg 2005;79:303-7.
4. England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura: a clinicopathologic review of 223 cases. Am J Surg Pathol 1989;13:640-58
5. Takahama M, Kushibe K, Kawaguchi T, Kimura M, Taniguchi S. Video-assisted thoracoscopic surgery is a promising treatment for solitary fibrous tumors of the pleura. Chest 2004;125:1144-7.
6. Magdeleinat P, Alifano M, Petino A, Rochais JP, Dulmet E, Galateau F, Icard Regnard JP. Solitary fibrous tumors of the pleura: clinical characteristics, surgical treatment and outcome. Eur J Cardiothorac Surg 2002;21:1087-93.
7. Cardillo G, Facciolo F, Cavazzana AO, Capece G, Gasparri R, Martelli M. Localized (solitary) fibrous tumors of the pleura: an analysis of 55 patients. Ann Thorac Surg 2000;70:1808-12.
8. Sandvliet RH, Heysteeg M, Paul MA. A large thoracic mass in a 57 year old patient. Chest 2000;117:897-900.

9. Robinson LA. Solitary Fibrous Tumor of The Pleura. Cancer Control 2006 Oct 13 (4) 264-9.
10. Khan JH, Rahman SB, Clary-Macy C, Kerlan RK, George TL, Hall TS, Jablons DM. Giant solitary fibrous tumor of the pleura. Ann Thorac Surg 1998;65:1461-4.
11. Biçer M, Yaldız S, Gürsoy S, Ülgan M. A case of giant benign localized fibrous tumor of the pleura. Eur J Cardiothorac Surg 1998;14:211-3.
12. Weiss B, Horton DA. Preoperative embolization of a massive solitary fibrous tumor of the pleura. Ann Thorac Surg 2002;73:983-5.
13. Shaker W, Meatchi T, Dusser D, Riquet M. An unusual presentation of solitary fibrous tumor of the pleura: right atrium and inferior vena cava compression. Eur J Cardiothorac Surg 2002;22:640-2.