Tc-99m-Diphosphonate Uptake in a Giant Ancient Schwannoma of the Arm

Abstract

We present a 77-year woman with a size of 9.5x9x7cm giant ancient schwannoma located in the lower arm. Increased activity accumulation in the tumor was seen on the Tc-99m-methylene diphosphonate bone scintigraphy. After excision of the tumor, Pathologic diagnosis could be illustrated as an ancient schwannoma. Previous studies reported that Schwannoma could be demonstrated with increased Tc-99m-diphosphonates activity accumulation but we speculate that this accumulation may be related to tissue types or atypical types of schwannoma. ©2006, Fırat Üniversitesi, Tıp Fakültesi

Keywords

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Kolun Dev Antik Schwannom'unda Tc-99m Difosfonat Tutulumu

Abstract

Kolda yerleşik 9.5x9x7cm boyutta dev antik schwannom'lu 77 yaşında bayanı sunmaktayız. Tc-99m-metilen difosfonat kemik sintigrafisinde tümörde artmış aktivite birikimi izlendi. Tümörün eksizyonu sonrasında patolojik tanı antik schwannom olarak gösterildi. Önceki çalışmalarda schwannom'un artmış Tc-99m-difosfonat aktivite birikimi ile gösterilebildiği yayınlanmıştır fakat biz birikimin schwannom'un doku tipleriyle veya atipik çeşitleri ile alakalı olabileceğini düşünmekteyiz. ©2006, Fırat Üniversitesi, Tıp Fakültesi

Keywords

• Sinir tümörü, schwannoma, sintigrafi, Tc-99m-medronat

References

1. Torossian JM, Augey F, Salle M et al. Giant foot schwannoma. British journal of plastic surgery 2001; 54: 74-76.
2. Schetthauer BW, Woodruff JM, Erlandson RA. Atlas of tumor pathology. Tumors of peripheral nervous system. 3rd series, fascicle 24, AFIP, Washington DC; 1999: 105-170.
3. Liebau C, Baltzer AW, Schneppenheim M, et al. Isolated peripheral neurilemoma attached to the tendon of the flexor digitorum longus muscle. Arch Orthop Trauma Surg. 2003; 123: 98-101
4. Enzinger FM, Weiss SW. Soft tissue tumors. 3rd edition, St. Louis-Mosby; 1996: 829-837.
5. Dodd LG, Marom EM, Dash RC, et al. Fine-needle aspiration cytology of ancient schwannoma. Diagn Cytopathol, 1999; 20: 307-311.
6. Rettenbacher T, Sogner P, Springer P, et al. Schwannoma of the brachial plexus: cross-sectional imaging diagnosis using CT, sonography, and MR imaging. Eur Radiol. 2003; 13: 1872-1875.
7. Maini CL, Cioffi RP, Tofani A, et al. Indium-111 octreotide scintigraphy in neurofibromatosis. Eur J Nucl Med. 1995; 22: 201-206.
8. Kobayashi H, Kotoura Y, Sakahara H, et al. Schwannoma of the extremities: comparison of MRI and pentavalent technetium- 99m-dimercaptosuccinic acid and gallium-67-citrate scintigraphy. J Nucl Med. 1994; 35: 1174-1178.

9. Ahmed AR, Watanabe H, Aoki J, Shinozaki T, Takagishi K. Schwannoma of the extremities: the role of PET in preoperative planning. Eur J Nucl Med. 2001; 28: 1541-1551.
10. Charabi S, Lassen NA, Jacobsen GK, et al. Diagnosis and growth evaluation of vestibular schwannomas by SPECT combined with TL-201 thallium. Ugeskr Laeger. 1999; 161: 2673-2678.
11. Von Moll L, McEwan AJ, Shapiro B, et al. Iodine-131 MIBG scintigraphy of neuroendocrine tumors other than pheochromocytoma and neuroblastoma. J Nucl Med. 1987; 28: 979-988.
12. Maini A, Tripathi M, Shekar N C, Malhotra A. Sciatic schwannoma of the thigh detected on bone scan: a case report. Clin Imaging. 2003; 27: 191-193.
13. Kabul Tarihi: 22.11.2005