BibTex RIS Cite

Comparison of Tenoxicam and with Paracetamol at Right Mediolateral Episiotomies For Analgesia

Year 2012, Volume: 17 Issue: 2, 76 - 79, 01.04.2012

Abstract

Objective: The study is performed to compare the analgesic effect of tenoxicam supposotories and paracetamol pill for management of right mediolateral episiotomy repair. Materials and Methods: A total of 66 patients who gave birth vaginally with right mediolateral episitomy were randomly assigned to receive 40mg tenoxicam supposotories plus 3x1 placebo pill/po. (Group 1, n=33) or 3X500 mg paracetamol pill/po. plus placebo supposotories ( Group 2, n=33) after episiotomy repair and postpartum three days. Pain ratings were recorded before, first and 24 hours after medications. Verbal rating scale (VRS) and visual analog scale (VAS) used for pain record. Student T test, X 2 test, Mann Whitney U and Wilcoxon Rank Test used for statistical analysis and Spearman correlation analysis used for comparison between VRS and VAS (rs, n, p). Results: Tenoxicam supposotories is more effective analgesic than paracetamol pill for right mediolateral episiotomies pain. At G1 first hour VRS (3±0.5 point), VAS (6±1.1 point); at G2 first hour VRS (3.4±0.5point ) VAS (6.8±0.8 point) and this difference found statistically significant (p

References

  • Cheung LK, Rodrigo C. Tenoxicam for pain relief following third molar surgery. Anesth Pain Control Dent 1992; 1: 229- 33.
  • Roelofse JA, Swart LC, Stander IA. An observer-blind randomised parallel group study comparing the efficacy and tolerability of tenoxicam and piroxicam in the treatment of post-operative pain after oral surgery. J Dent Assoc S Afr 1996; 51: 707-11.
  • Skovlund E, Fyllingen G, Landre H, Nesheim BI. Comparison of postpartum pain treatments using a sequential trial design: II. Naproxen versus paracetamol. Eur J Clin Pharmacol 1991; 40: 539-42.
  • Varrassi G, Marinangeli F, Agro F, et al. A double-blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: analgesic efficacy and tolerability after gynecologic surgery. Anesth Analg 1999; 88: 611-6.
  • Montgomery JE, Sutherland CJ, Kestin IG, Sneyd JR. Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination. Br J Anaesth 1996; 77: 445-7.
  • Schachtel BP, Thoden WR, Baybutt RI. Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain. J Clin Pharmacol 1989; 29: 550-3.
  • Rubin A, Winter L Jr. A double-blind randomized study of an aspirin/caffeine combination versus acetaminophen/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain. J Int Med Res 1984; 12: 338-45.
  • Aguilar JL, Rincon R, Domingo V, Espachs P, Preciado MJ, Vidal F. Absence of an early pre-emptive effect after thoracic extradural bupivacaine in thoracic surgery. Br J Anaesth 1996; 76: 72-6.
  • Reading AE. A comparison of pain rating scales. J Psychosom Res 1980; 24: 119-24.
  • Peter EA, Janssen PA, Grange CS, Douglas MJ. Ibuprofen versus acetaminophen with codeine for the relief of perineal pain after childbirth: a randomized controlled trial. CMAJ 2001; 165: 1203-9.
  • Huang KC, Wolfe WM, Tsueda K, Simpson PM, Caissie KF. Effects of meclofenamate and acetaminophen on abdominal pain following tubal occlusion. Am J Obstet Gynecol 1986; 155: 624-9.
  • Dahl V, Erno PE, Raeder JC. No analgesic effect of ibuprofen or paracetamol vs placebo for hysterectomies. Eur J Pain 1997; 1: 31-5.
  • Hyllested M, Jones S, Pedersen JL, Kehlet H. Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review. Br J Anaesth 2002; 88: 199-214.
  • Van Lancker P, Vandekerckhove B, Cooman F. The analgesic effect of preoperative administration of propacetamol, tenoxicam or a mixture of both in arthroscopic, outpatient knee surgery. Acta Anaesthesiol Belg 1999; 50: 65-9.
  • Voilley N, de Weille J, Mamet J, Lazdunski M. Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors. J Neurosci 2001; 21: 8026-33.
  • Gönderilme Tarihi: 16.07.2011

Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam ile Parasetamolün Karşılaştırılması

Year 2012, Volume: 17 Issue: 2, 76 - 79, 01.04.2012

Abstract

Amaç: Sağ medyolateral epizyotomi sonucu ortaya çıkan ağrı üzerine tenoksikam süpozituar ile parasetamol tablet kullanımının etkilerinin karşılaştırılması. Gereç ve Yöntem: Sağ medyolateral epizyotomi ile doğum yaptırılan 66 hasta,randomize, prospektif, tek kör olarak iki gruba ayrıldı. Grup 1 (n=33): Tenoksikam süpozituar ve plasebo tablet, Grup 2 (n=33): parasetamol tablet ve plasebo süpozituar grubu. Epizyotomi tamirini takiben Grup 1’deki hastalara rektal yoldan 40 mg’lık tenoksikam süpozituar ve 3x1 plasebo tablet/po, Grup 2’deki hastalara ise 3x1 parasetamol 500 mg tablet/po ve plasebo süpozituar başlandı. Birinci ve 24. saatlerde Verbal rating skala (VRS) ve vizüel analog skala (VAS) kullanılarak ağrıları değerlendirildi. Verilerin istatistiksel analizinde X2,Student T, Mann Whitney U ve Wilcoxon Rank testleri kullanıldı (p

References

  • Cheung LK, Rodrigo C. Tenoxicam for pain relief following third molar surgery. Anesth Pain Control Dent 1992; 1: 229- 33.
  • Roelofse JA, Swart LC, Stander IA. An observer-blind randomised parallel group study comparing the efficacy and tolerability of tenoxicam and piroxicam in the treatment of post-operative pain after oral surgery. J Dent Assoc S Afr 1996; 51: 707-11.
  • Skovlund E, Fyllingen G, Landre H, Nesheim BI. Comparison of postpartum pain treatments using a sequential trial design: II. Naproxen versus paracetamol. Eur J Clin Pharmacol 1991; 40: 539-42.
  • Varrassi G, Marinangeli F, Agro F, et al. A double-blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: analgesic efficacy and tolerability after gynecologic surgery. Anesth Analg 1999; 88: 611-6.
  • Montgomery JE, Sutherland CJ, Kestin IG, Sneyd JR. Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination. Br J Anaesth 1996; 77: 445-7.
  • Schachtel BP, Thoden WR, Baybutt RI. Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain. J Clin Pharmacol 1989; 29: 550-3.
  • Rubin A, Winter L Jr. A double-blind randomized study of an aspirin/caffeine combination versus acetaminophen/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain. J Int Med Res 1984; 12: 338-45.
  • Aguilar JL, Rincon R, Domingo V, Espachs P, Preciado MJ, Vidal F. Absence of an early pre-emptive effect after thoracic extradural bupivacaine in thoracic surgery. Br J Anaesth 1996; 76: 72-6.
  • Reading AE. A comparison of pain rating scales. J Psychosom Res 1980; 24: 119-24.
  • Peter EA, Janssen PA, Grange CS, Douglas MJ. Ibuprofen versus acetaminophen with codeine for the relief of perineal pain after childbirth: a randomized controlled trial. CMAJ 2001; 165: 1203-9.
  • Huang KC, Wolfe WM, Tsueda K, Simpson PM, Caissie KF. Effects of meclofenamate and acetaminophen on abdominal pain following tubal occlusion. Am J Obstet Gynecol 1986; 155: 624-9.
  • Dahl V, Erno PE, Raeder JC. No analgesic effect of ibuprofen or paracetamol vs placebo for hysterectomies. Eur J Pain 1997; 1: 31-5.
  • Hyllested M, Jones S, Pedersen JL, Kehlet H. Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review. Br J Anaesth 2002; 88: 199-214.
  • Van Lancker P, Vandekerckhove B, Cooman F. The analgesic effect of preoperative administration of propacetamol, tenoxicam or a mixture of both in arthroscopic, outpatient knee surgery. Acta Anaesthesiol Belg 1999; 50: 65-9.
  • Voilley N, de Weille J, Mamet J, Lazdunski M. Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors. J Neurosci 2001; 21: 8026-33.
  • Gönderilme Tarihi: 16.07.2011
There are 16 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Ekrem Sapmaz This is me

Aygen Çelik Altungül This is me

Publication Date April 1, 2012
Published in Issue Year 2012 Volume: 17 Issue: 2

Cite

APA Sapmaz, E., & Altungül, A. Ç. (2012). Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam ile Parasetamolün Karşılaştırılması. Fırat Tıp Dergisi, 17(2), 76-79.
AMA Sapmaz E, Altungül AÇ. Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam ile Parasetamolün Karşılaştırılması. Fırat Tıp Dergisi. April 2012;17(2):76-79.
Chicago Sapmaz, Ekrem, and Aygen Çelik Altungül. “Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam Ile Parasetamolün Karşılaştırılması”. Fırat Tıp Dergisi 17, no. 2 (April 2012): 76-79.
EndNote Sapmaz E, Altungül AÇ (April 1, 2012) Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam ile Parasetamolün Karşılaştırılması. Fırat Tıp Dergisi 17 2 76–79.
IEEE E. Sapmaz and A. Ç. Altungül, “Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam ile Parasetamolün Karşılaştırılması”, Fırat Tıp Dergisi, vol. 17, no. 2, pp. 76–79, 2012.
ISNAD Sapmaz, Ekrem - Altungül, Aygen Çelik. “Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam Ile Parasetamolün Karşılaştırılması”. Fırat Tıp Dergisi 17/2 (April 2012), 76-79.
JAMA Sapmaz E, Altungül AÇ. Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam ile Parasetamolün Karşılaştırılması. Fırat Tıp Dergisi. 2012;17:76–79.
MLA Sapmaz, Ekrem and Aygen Çelik Altungül. “Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam Ile Parasetamolün Karşılaştırılması”. Fırat Tıp Dergisi, vol. 17, no. 2, 2012, pp. 76-79.
Vancouver Sapmaz E, Altungül AÇ. Sağ Medyolateral Epizyotomi Vakalarında Ağrı Kesici Olarak Tenoksikam ile Parasetamolün Karşılaştırılması. Fırat Tıp Dergisi. 2012;17(2):76-9.