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Chronic Tobacco Snuff-Induced Columellar Squamous Cell Carcinoma: A Case Report

Year 2011, Volume: 16 Issue: 4, 223 - 225, 01.08.2011

Abstract

In this article, we presented a 57-year-old woman with a history of snuff abuse for 16 years and developed squamous cell carcinonoma in the columellar skin. Primary cancer of nasal columella is extremely rare. This is a very agressive tumor and if not resected adequately it can easily spread to adjacent structures.. These tumors should be treated radically. The tumor was resected and defect was reconstructed with left nasolabial sulcus flap in this case. Close follow-up is required because of high recurrence rate. We try to discuss the behavior of these tumors, staging, treatment modalities and prognostic factors.

References

  • 1. Oriba HA, Snow SN. Tumours of the nasal columella treated by Mohs micrographic surgery. Laryngoscope 1997; 107: 1647–1650.
  • 2. Conley J. Cancer of the skin of the nose. Ann Otol Rhinol Laryngol 1974; 83: 2-8.
  • 3. Fornelli RA, Fedok FG, Wilson EP, Rodman SM. Squamous cell carcinoma of the anterior nasal cavity: a dual institution review. Otolaryngol Head Neck Surg 2000; 123: 207–210.
  • 4. Choussy O, Babin E, Temam S, et al. Squamous cell carcinoma of nasal of nasal columella: a retrospective study of 66 cases from the GETTEC. Eur Arch of Otorhinolaryngol 2008; 265: 35-41.
  • 5. Maruyama Y, Iwahira Y. The axial nasodorsum flap, Plast Reconstr Surg 1997; 99; 1873-1877.
  • 6. Mignogna FV, Garay KF. Surgical rescue of recurrent carcinoma of the nasal columella. Am J Surg 1996; 170: 453- 456.
  • 7. Mendenhall NP, Parsons JT, Cassisi NJ. Carcinoma of the nasal vestibule treated with radiation therapy. Laryngoscope 1987; 97: 626–632.
  • 8. Sreedharan S, Hegde MC, Pai R, et al. Snuff-induced malignancy of the nasal vestibule: a case report. Am J Otolaryngol 2007; 28: 353-356.
  • 9. Sapundzhiev N, Werner JA. Nasal snuff: historical review and health related aspects. J Laryngol Otol 2003; 117: 686-691.
  • 10. Koppang N, Rivenson A, Dahle HK, et al. A study of tobacco carcinogenesis, LIII: carcinogenicity of N Vnitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone (NNK) in mink (Mustela vison). Cancer Lett 1997; 111: 167-171.
  • 11. Larsson PA, Johansson SL, Vahlne A, et al. Snuff tumorigenesis: effects of long-term snuff administration after initiation with 4- nitroquinolone- N -oxide and herpes simplex virus type 1. J Oral Pathol Med 1989; 18: 187-191.
  • 12. Wang CC. Treatment of carcinoma of the nasal vestibule by irradiation. Cancer 1976; 38: 100–106.
  • 13. Wong CS, Cummings BJ, Elkhakim T, Briant TD. External irradiation for squamous cell carcinoma of the nasal vestibule. Int J Radiat Oncol Biol Phys 1986; 12: 1943–1946.

Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu

Year 2011, Volume: 16 Issue: 4, 223 - 225, 01.08.2011

Abstract

Bu yazıda 16 yıldır burnuna tütün çekme hikayesi olan ve kolumellar ciltte skuamoz hücreli kanser gelişen 57 yaşında bayan hastayı sunduk. Nazal kolumellanın primer kanseri oldukça nadirdir. Bu çok agresif olan ve yeterince rezeke edilmediğinde kolaylıkla çevre yapılara yayılabilen bir tümördür. Bu tümörler radikal olarak tedavi edilmelidir. Bu vakada tümör rezeke edildi ve oluşan defekt nazolabial sulkus flebiyle rekonstrukte edildi. Yüksek rekürrans oranı nedeniyle yakın takip gereklidir. Bu tümörlerin davranışı, evrelemesi ve tedavi seçeneklerini tartışmaya çalıştık.

References

  • 1. Oriba HA, Snow SN. Tumours of the nasal columella treated by Mohs micrographic surgery. Laryngoscope 1997; 107: 1647–1650.
  • 2. Conley J. Cancer of the skin of the nose. Ann Otol Rhinol Laryngol 1974; 83: 2-8.
  • 3. Fornelli RA, Fedok FG, Wilson EP, Rodman SM. Squamous cell carcinoma of the anterior nasal cavity: a dual institution review. Otolaryngol Head Neck Surg 2000; 123: 207–210.
  • 4. Choussy O, Babin E, Temam S, et al. Squamous cell carcinoma of nasal of nasal columella: a retrospective study of 66 cases from the GETTEC. Eur Arch of Otorhinolaryngol 2008; 265: 35-41.
  • 5. Maruyama Y, Iwahira Y. The axial nasodorsum flap, Plast Reconstr Surg 1997; 99; 1873-1877.
  • 6. Mignogna FV, Garay KF. Surgical rescue of recurrent carcinoma of the nasal columella. Am J Surg 1996; 170: 453- 456.
  • 7. Mendenhall NP, Parsons JT, Cassisi NJ. Carcinoma of the nasal vestibule treated with radiation therapy. Laryngoscope 1987; 97: 626–632.
  • 8. Sreedharan S, Hegde MC, Pai R, et al. Snuff-induced malignancy of the nasal vestibule: a case report. Am J Otolaryngol 2007; 28: 353-356.
  • 9. Sapundzhiev N, Werner JA. Nasal snuff: historical review and health related aspects. J Laryngol Otol 2003; 117: 686-691.
  • 10. Koppang N, Rivenson A, Dahle HK, et al. A study of tobacco carcinogenesis, LIII: carcinogenicity of N Vnitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone (NNK) in mink (Mustela vison). Cancer Lett 1997; 111: 167-171.
  • 11. Larsson PA, Johansson SL, Vahlne A, et al. Snuff tumorigenesis: effects of long-term snuff administration after initiation with 4- nitroquinolone- N -oxide and herpes simplex virus type 1. J Oral Pathol Med 1989; 18: 187-191.
  • 12. Wang CC. Treatment of carcinoma of the nasal vestibule by irradiation. Cancer 1976; 38: 100–106.
  • 13. Wong CS, Cummings BJ, Elkhakim T, Briant TD. External irradiation for squamous cell carcinoma of the nasal vestibule. Int J Radiat Oncol Biol Phys 1986; 12: 1943–1946.
There are 13 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Vefa Kınıs This is me

Ramazan Gun This is me

Salih Bakır This is me

Ediz Yorgancılar This is me

İsmail Topcu This is me

Ugur Fırat This is me

Publication Date August 1, 2011
Published in Issue Year 2011 Volume: 16 Issue: 4

Cite

APA Kınıs, V., Gun, R., Bakır, S., Yorgancılar, E., et al. (2011). Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu. Fırat Tıp Dergisi, 16(4), 223-225.
AMA Kınıs V, Gun R, Bakır S, Yorgancılar E, Topcu İ, Fırat U. Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu. Fırat Tıp Dergisi. August 2011;16(4):223-225.
Chicago Kınıs, Vefa, Ramazan Gun, Salih Bakır, Ediz Yorgancılar, İsmail Topcu, and Ugur Fırat. “Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu”. Fırat Tıp Dergisi 16, no. 4 (August 2011): 223-25.
EndNote Kınıs V, Gun R, Bakır S, Yorgancılar E, Topcu İ, Fırat U (August 1, 2011) Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu. Fırat Tıp Dergisi 16 4 223–225.
IEEE V. Kınıs, R. Gun, S. Bakır, E. Yorgancılar, İ. Topcu, and U. Fırat, “Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu”, Fırat Tıp Dergisi, vol. 16, no. 4, pp. 223–225, 2011.
ISNAD Kınıs, Vefa et al. “Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu”. Fırat Tıp Dergisi 16/4 (August 2011), 223-225.
JAMA Kınıs V, Gun R, Bakır S, Yorgancılar E, Topcu İ, Fırat U. Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu. Fırat Tıp Dergisi. 2011;16:223–225.
MLA Kınıs, Vefa et al. “Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu”. Fırat Tıp Dergisi, vol. 16, no. 4, 2011, pp. 223-5.
Vancouver Kınıs V, Gun R, Bakır S, Yorgancılar E, Topcu İ, Fırat U. Kronik Olarak Buruna Tütün Çekimine Bağlı Skuamoz Hücreli Karsinom: Olgu Sunumu. Fırat Tıp Dergisi. 2011;16(4):223-5.